Zobrazeno 1 - 4
of 4
pro vyhledávání: '"R. J. Radmer"'
Autor:
R J, Radmer, P A, Kollman
Publikováno v:
Journal of computer-aided molecular design. 12(3)
Three approximate free energy calculation methods are examined and applied to an example ligand design problem. The first of the methods uses a single simulation to estimate the relative binding free energies for related ligands that are not simulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::11d4fca87d114efe9f4960fe2209994a
https://pubmed.ncbi.nlm.nih.gov/9749366
https://pubmed.ncbi.nlm.nih.gov/9749366
Publikováno v:
Proteins. 32(4)
Free energy derivatives, pictorial representation of free energy changes (PROFEC) and free energy perturbation methods were employed to suggest the modifications that may improve the stability of a mutant T4 lysozyme with a S-2-amino-3-cyclopentylpro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4be52d6728a643c6567cd0e72482c498
https://pubmed.ncbi.nlm.nih.gov/9726415
https://pubmed.ncbi.nlm.nih.gov/9726415
Publikováno v:
Progress in Photosynthesis Research ISBN: 9789401080804
It is surprising that any organism can continue its metabolic functions in a perdeuterated state since virtually all metabolic processes involve hydrogen bonding, and the dissociation constant of D20 is an order of magnitude lower than that of H20. N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65c9fd81a43138d9bbb21925918f32cb
https://doi.org/10.1007/978-94-009-3535-8_141
https://doi.org/10.1007/978-94-009-3535-8_141
Publikováno v:
14th Aerospace Sciences Meeting.
We describe an approach for the remote detection and characterization of life in planetary soil samples. A mass spectrometer is used as the central sensor to monitor changes in the gas phase in eleven test cells filled with soil. Many biological assa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2671adc27cb97ba59dc4230b9b532cc
https://doi.org/10.2514/6.1976-125
https://doi.org/10.2514/6.1976-125