Zobrazeno 1 - 6
of 6
pro vyhledávání: '"R. J. Powel"'
Publikováno v:
Journal of Neurochemistry. 59:2087-2093
Neomycin appears as a full agonist and spermidine as a partial agonist at the site where polyamines enhance 1-[1-(2-thienyl)cyclohexyl][3H]piperidine ([3H]TCP) binding on the N-methyl-D-aspartate (NMDA) receptor. Other aminoglycosides also enhance [3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb45a77a8dff39e2e8ab9858e7f3959d
https://doi.org/10.1111/j.1471-4159.1992.tb10099.x
https://doi.org/10.1111/j.1471-4159.1992.tb10099.x
Autor:
Andre I. Salama, D. LaMonte, Thomas J. Mangano, Jitendra Patel, P. J. Warwick, William C. Zinkand, R. J. Powel, Richard A. Keith, M. Britt, Linda M. Pullan, Robert J. Stumpo, M. J. Chapdelaine
Publikováno v:
Journal of Neurochemistry. 55:1346-1351
HA-966 (1-hydroxy-3-aminopyrrolidone-2) is an antagonist at the glycine allosteric site of the N-methyl-D-aspartate receptor ionophore complex. Unlike presently known glycine antagonists, HA-966 is chiral. We report stereoselectivity for the (R)-enan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f63ce139954a65375366071e61167d8
https://doi.org/10.1111/j.1471-4159.1990.tb03145.x
https://doi.org/10.1111/j.1471-4159.1990.tb03145.x
Autor:
L M, Pullan, R J, Powel
Publikováno v:
Neuroscience letters. 148(1-2)
We compared, for a number of ligands to the two receptors, the displacement of [3H]strychnine binding to the glycine-gated chloride channel of spinal cord and brainstem synaptic membranes to the displacement of [3H]glycine binding to the NMDA recepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6a07bf5848dbe2e9bb110b3f34527c2d
https://pubmed.ncbi.nlm.nih.gov/1338650
https://pubmed.ncbi.nlm.nih.gov/1338650
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 262(2)
The effects of N-(3-aminopropyl)-1,10-diaminodecane (APDA10) on the N-methyl-D-aspartate (NMDA) receptor/ion channel complex were investigated. In the presence of 100 microM glutamate and 100 microM glycine, APDA10 had biphasic effects on the binding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9b51717b7ac837d1910415da86a3e6f9
https://pubmed.ncbi.nlm.nih.gov/1354252
https://pubmed.ncbi.nlm.nih.gov/1354252
Publikováno v:
Research communications in chemical pathology and pharmacology. 75(3)
We studied the influence of chronic moricizine hydrochloride (MRZ) treatment on the drug's pharmacokinetics and on drug metabolizing enzyme activities in rats. Separate groups of 8 rats (4 males and 4 females) were treated with 40 and 100 mg/kg oral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e4e34399782c78746f6b517274b2171e
https://pubmed.ncbi.nlm.nih.gov/1509197
https://pubmed.ncbi.nlm.nih.gov/1509197
Autor:
L M, Pullan, M, Britt, M J, Chapdelaine, R A, Keith, D, LaMonte, T J, Mangano, J, Patel, R J, Powel, R J, Stumpo, P J, Warwick
Publikováno v:
Journal of neurochemistry. 55(4)
HA-966 (1-hydroxy-3-aminopyrrolidone-2) is an antagonist at the glycine allosteric site of the N-methyl-D-aspartate receptor ionophore complex. Unlike presently known glycine antagonists, HA-966 is chiral. We report stereoselectivity for the (R)-enan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d4e6ded9c6b7a8268e4d98a3736b1c6e
https://pubmed.ncbi.nlm.nih.gov/1975835
https://pubmed.ncbi.nlm.nih.gov/1975835