Zobrazeno 1 - 10
of 50
pro vyhledávání: '"R. J. Muschel"'
Autor:
A. E. Yuzhalin, A. N. Gordon-Weeks, M. L. Tognoli, K. Jones, B. Markelc, R. Konietzny, R. Fischer, A. Muth, E. O’Neill, P. R. Thompson, P. J. Venables, B. M. Kessler, S. Y. Lim, R. J. Muschel
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Colorectal cancers (CRCs) often develop into untreatable metastatic disease of the liver. Here the authors report the modification of extracellular matrix proteins by citrullination in CRC metastases to the liver and propose that inhibition of citrul
Externí odkaz:
https://doaj.org/article/792ceadda95d4235966746de3a3f6359
Publikováno v:
Oncogene
Myeloid cells promote the development of distant metastases, but little is known about the molecular mechanisms underlying this process. Here we have begun to uncover the effects of myeloid cells on cancer cells in a mouse model of liver metastasis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d73d46fdca7d851418f7f36d0fd8c1fa
https://pubmed.ncbi.nlm.nih.gov/27086923
https://pubmed.ncbi.nlm.nih.gov/27086923
Publikováno v:
British Journal of Cancer
Although it is generally accepted that proteolytic degradation is an important mechanism used by malignant cells in the process of metastasis, comparatively little is known about the regulation of molecules responsible for proteolysis and how they be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8335c9e51a8097f34ed237312339a24
https://doi.org/10.1038/sj.bjc.6690385
https://doi.org/10.1038/sj.bjc.6690385
Autor:
H C Silva, H Z Hill, F Kueppers, G J Hill, W G McKenna, W Li, L J Wolansky, S. Zhou, R J Muschel
Publikováno v:
Melanoma Research. 9:40-50
A multitherapy resistance (MTR) factor produced by Cloudman S91 mouse melanoma cells rescues a responsive cell line after gamma-irradiation, short wavelength ultraviolet light, mitomycin C, vinblastine and actinomycin D. A similar activity with respe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e238259ac3c38b6664146a53336e01c
https://doi.org/10.1097/00008390-199902000-00006
https://doi.org/10.1097/00008390-199902000-00006
Publikováno v:
Journal of Biological Chemistry. 273:31505-31509
Cyclin B1 mRNA is expressed temporally throughout the cell cycle with peak expression in G2 and M phase. Both transcriptional and posttranscriptional controls are important for this cell cycle-dependent regulation of cyclin B1 mRNA. In this study, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa1a7c362ab00c2fb5711557a46ebb7a
https://doi.org/10.1074/jbc.273.47.31505
https://doi.org/10.1074/jbc.273.47.31505
Autor:
R J, Muschel, J, Hua
Publikováno v:
Methods in molecular medicine. 58
One means of testing a candidate gene for involvement in the metastatic process is to alter the expression of that gene in a tumor cell and then to test the metastatic potential of the altered cells. In designing such experiments, it is crucial to ta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::745dbba6cec3c7e82981539e278044d3
https://pubmed.ncbi.nlm.nih.gov/21340858
https://pubmed.ncbi.nlm.nih.gov/21340858
Publikováno v:
Methods in enzymology. 333
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ae491739d711bb11ec8fbc015d3b7e71
https://pubmed.ncbi.nlm.nih.gov/11400344
https://pubmed.ncbi.nlm.nih.gov/11400344
Autor:
E J, Bernhard, R J, Muschel
Publikováno v:
Methods in enzymology. 333
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a2101aa8d7f6722fcfddd1c7fb244afa
https://pubmed.ncbi.nlm.nih.gov/11400358
https://pubmed.ncbi.nlm.nih.gov/11400358
Autor:
A K, Gupta, V J, Bakanauskas, G J, Cerniglia, Y, Cheng, E J, Bernhard, R J, Muschel, W G, McKenna
Publikováno v:
Cancer research. 61(10)
The critical pathways determining the resistance of tumor cells to ionizing radiation are poorly defined. Because the ras oncogene, a gene activated in many human cancers treated with radiotherapy, can induce increased radioresistance, we have asked
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::09222d5820ed3a98dce6b520c07432f5
https://pubmed.ncbi.nlm.nih.gov/11358856
https://pubmed.ncbi.nlm.nih.gov/11358856
Publikováno v:
Cancer research. 61(5)
Many tumors contain extensive regions of hypoxia. Because hypoxic cells are markedly more resistant to killing by radiation, repeated attempts have been made to improve the oxygenation of tumors to enhance radiotherapy. We have studied the oxygenatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1de51dd1d007fde44dfd98f0d6ece428
https://pubmed.ncbi.nlm.nih.gov/11280800
https://pubmed.ncbi.nlm.nih.gov/11280800