Zobrazeno 1 - 10
of 42
pro vyhledávání: '"R. J. M. Croughs"'
Publikováno v:
Clinical Endocrinology. 33:619-624
SUMMARY Eleven patients with prolactin-producing pituitary adenomas were treated with the new non-ergot, long-acting dopamine agonist, CV 205–502, for a period of 2–18 months (mean 11 months). Tumour volumes ranged from 1–9 to 64 ml in seven pa
Publikováno v:
Molecular and Cellular Endocrinology, 111(1), 13-19. Elsevier Ireland Ltd
In pituitary-dependent hyperadrenocorticism (Cushing's disease), the disturbed regulation of ACTH secretion is associated with neoplastic transformation of corticotropic cells. As these two phenomena are almost indissolubly connected, it is of prime
Autor:
J. W. Van't Verlaat, R. J. M. Croughs
Publikováno v:
Clinical Endocrinology. 34:175-178
The present study describes the effect on plasma prolactin values and tumour size of bromocriptine withdrawal in 12 patients who had been treated for macroprolactinomas for a period of 3.5-7 (mean 4.9) years. Pretreatment plasma prolactin values rang
Publikováno v:
Journal of Endocrinological Investigation. 14:197-200
We have measured alpha-MSH in plasma of normal subjects and subjects with various diseases of the pituitary-adrenocortical system using a radioimmunoassay with a sensitivity of 1.2 pmol/l. No alpha-MSH could be detected in plasma of normal subjects (
Publikováno v:
Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques. 17:71-73
Nineteen patients, seven women and twelve men, with macroprolactinomas characterized by extrasellar extension and basal prolactin levels above 6 U/I were treated with 10-20 mg bromocriptine daily in four divided doses for a mean period of 3.4 years (
Publikováno v:
European journal of endocrinology. 138(3)
Extrinsic factors such as hypothalamic hormones or intrapituitary growth factors may stimulate clonal expansion of a genomically altered cell and therefore play a role in pituitary tumorigenesis. Here we report on the effects of the hypophysiotrophic
Autor:
Ad Rijnberk, R. J. M. Croughs, Björn P. Meij, I. S. van Leeuwen, P. A. Van Wijk, Jan A. Mol, E. P. M. Sprang
Publikováno v:
Journal of endocrinological investigation. 20(1)
Pituitary tumorigenesis is now generally regarded as a multistep process of genomic damage leading to uncoupling of interdependent systems that control cell proliferation and differentiation. The alterations include mutations in genes encoding for pr
Autor:
R. J. M. Croughs, T.W.A. de Bruin
Publikováno v:
The Netherlands journal of medicine. 49(4)
Jet lag is an ill-defined phenomenon resulting from rapid transmeridional flight and is considered to be due to desynchronization of circadian rhythms. The role of the pineal gland hormone, melatonin, in the synchronization of biological rhythms has