Zobrazeno 1 - 10
of 21
pro vyhledávání: '"R. J. Handa"'
Publikováno v:
Am J Physiol Heart Circ Physiol
In utero exposure to glucocorticoids in late gestation programs changes in cardiovascular function. The objective of this study was to determine the degree to which angiotensin II mediates sex-biased changes in autonomic function as well as basal and
Publikováno v:
Journal of neuroendocrinology. 24(1)
Oestradiol exerts a profound influence upon multiple brain circuits. For the most part, these effects are mediated by oestrogen receptor (ER)α. We review here the roles of ERβ, the other ER isoform, in mediating rodent oestradiol-regulated anxiety,
Autor:
Z, Khalkhali-Ellis, E A, Seftor, D R, Nieva, R J, Handa, R H, Price, D A, Kirschmann, V M, Baragi, R V, Sharma, R C, Bhalla, T L, Moore, M J, Hendrix
Publikováno v:
The Journal of rheumatology. 27(7)
Despite increasing evidence regarding the significance of sex hormones in rheumatoid arthritis (RA), their etiopathological role and potential longterm effect on joint destruction remain unclear. We hypothesized that estrogen receptors (ER-alpha) are
Publikováno v:
Biology of reproduction. 60(6)
As a first step in determining possible influences of the newly discovered estrogen receptor (ER)-beta on reproduction, we have localized mRNA for ER-beta within the male sheep hypothalamus using in situ hybridization and a rat ER-beta cRNA probe. Hi
Publikováno v:
Endocrinology. 139(12)
Estrogen plays a key role in the regulation of many pituitary hormones. The presence of estrogen receptor-beta (ER beta) messenger RNA (mRNA) has been demonstrated in the adult anterior pituitary by RT-PCR to be at a level much greater than that of E
Autor:
M E, Wilson, R J, Handa
Publikováno v:
Biology of reproduction. 59(2)
In the prepubertal female rat, a transient and selective increase in FSH secretion and mRNA expression by the pituitary gland occurs toward the end of the second postnatal week of life. To begin to investigate the possibility that activin may play a
Publikováno v:
Alcoholism, clinical and experimental research. 22(4)
Previous studies have shown that female rats consume significantly more water than males on a weight basis. Because exposure to alcohol during the last week of gestation is associated with incomplete behavioral defeminization in male rats, we examine
Autor:
R Y, Yukhananov, R J, Handa
Publikováno v:
Brain research. 764(1-2)
Gonadal steroids modulate activity of the hypothalamo-pituitary-adrenal axis (HPA) following stress, but the regulatory pathways of this modulation are unknown. A possible site of action is the synthesis of CRH and/or enkephalin in cells of the parav
Autor:
A H, Nagahara, R J, Handa
Publikováno v:
Alcoholism, clinical and experimental research. 21(4)
The effects of prenatal alcohol exposure on both behavioral and neurobiological measures may be dependent, in part, on the age of the animal. Previous evidence from our laboratory has shown a delay-dependent memory deficit in young adult fetal alcoho
Publikováno v:
Synapse (New York, N.Y.). 23(1)
Previously, research elucidating steroid hormone actions in the central nervous system has focused on their role in sexual reproduction and maintaining homeostasis. The hippocampus is a target of steroid modulation and is involved in the development