Zobrazeno 1 - 6
of 6
pro vyhledávání: '"R. J. Gerson"'
Publikováno v:
Drug Investigation. 2:18-28
Lovastatin (mevinolin) [LV], simvastatin (epistatin) [SV] and pravastatin (eptastatin) [PVA] are indicated in the treatment of hypercholesterolaemia and are potent inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase. Beagle dogs w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee404b935b4dea4e998b46e66eb11468
https://doi.org/10.1007/bf03258190
https://doi.org/10.1007/bf03258190
Publikováno v:
Neurotoxicology and teratology. 19(4)
The potential of emamectin benzoate (EB) to cause developmental neurotoxicity in Sprague-Dawley rats was assessed using a study design by the US EPA. Dosages of 0 (deionized water), 0.1, 0.6, or 3.6 mg/kg/day were administered at 5 ml/kg by oral gava
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::932ad42f323cb8cc910c81bebd420774
https://pubmed.ncbi.nlm.nih.gov/9253010
https://pubmed.ncbi.nlm.nih.gov/9253010
Publikováno v:
Fundamental and applied toxicology : official journal of the Society of Toxicology. 16(2)
L-645, 164, a potent inhibitor of hydroxymethylglutarylcoenzyme A (HMG-CoA) reductase, is a structurally unique, synthetic monofluorinated-biphenyl that was administered to beagle dogs at dosages of 2, 10, or 50 mg/kg/day for 14 weeks to evaluate its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ca8c8cf9e235a86ce4601ef708487eb8
https://pubmed.ncbi.nlm.nih.gov/2055362
https://pubmed.ncbi.nlm.nih.gov/2055362
Publikováno v:
Carcinogenicity ISBN: 9783642648106
Cancer is a complex, multistage, multimechanism phenomenon. Despite this, long-term rodent carcinogenicity studies have been the principal means used to assess the potential carcinogenic effect of compounds. Unfortunately, decades of carcinogenicity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab4e4919d1f9753ebd1f6b984e19bf79
https://doi.org/10.1007/978-3-642-61364-7_11
https://doi.org/10.1007/978-3-642-61364-7_11
Autor:
J L, Farber, R J, Gerson
Publikováno v:
Pharmacological reviews. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::46779b5feac229154efff6f4a91d2e23
https://pubmed.ncbi.nlm.nih.gov/6382357
https://pubmed.ncbi.nlm.nih.gov/6382357
Autor:
R J, Gerson, Z A, Shaikh
Publikováno v:
Biochemical pharmacology. 33(2)
Studies measuring the uptake of cadmium or mercury in isolated hepatocytes demonstrated that hepatocytes accumulated more cadmium than mercury in serum-containing medium, serum-free medium, or balanced salt solution. The preferential hepatocellular a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0c1dda1a3cc0b8966415f17d6e95d46f
https://pubmed.ncbi.nlm.nih.gov/6704146
https://pubmed.ncbi.nlm.nih.gov/6704146