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pro vyhledávání: '"R. J. Gayton"'
Autor:
R. J. Gayton, G. J. Dockray, R.G. Williams, A. Varro, K. A. Sharkey, H. Desmond, Helen E. Raybould, A-C Jonsson
Publikováno v:
Annals of the New York Academy of Sciences. 448:32-43
Cholecystokinin octapeptide is the predominant representative of the gastrin-CCK family in the central nervous system. Other forms occur in low concentrations, or restricted locations, as do the gastrins. The pathways of biosynthetic processing can n
Publikováno v:
Neuropharmacology. 17:549-551
(+)-Naloxone was tested, using the technique of microiontophoresis, for its ability to antagonise the depressant effects of opioid peptides on rat medullary neurones. It showed no antagonist activity, and may thus be valuable for confirming the stere
Publikováno v:
Nature. 305:328-330
The tetrapeptide Phe-Met-Arg-Phe-NH2 (FMRFamide) and peptides structurally related to it, have been isolated from molluscan ganglia1–3. They have widespread actions on both invertebrate and vertebrate tissues and there is increasing evidence that t
Publikováno v:
Centrally Acting Peptides ISBN: 9781349036707
Any discussion of the electrophysiological effects of opiate drugs in the central nervous system (CNS) should include effects on the electroencephalogram (EEG) and evoked potentials, as well as effects on single neurons. However, studies of ‘gross
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ff10f343a09545d998a144f35787948
https://doi.org/10.1007/978-1-349-03668-4_14
https://doi.org/10.1007/978-1-349-03668-4_14
Publikováno v:
British journal of pharmacology. 61(1)
Publikováno v:
Nature. 261(5559)
THE identification of a specific opiate receptor in mammalian brain1, and also of an endogenous morphine-like factor, enkephalin, which possesses potent opiate agonist activity peripherally2, raises the question of the possible physiological signific
Publikováno v:
The Journal of physiology. 232(2)
Autor:
R. J. Gayton
Publikováno v:
Nature. 298:275-276
Since the enkephalins were first isolated a number of opioid peptides have been discovered, including a heptapeptide with the sequence Tyr-Gly-Gly-Phe-Met-Arg-Phe (Met-enkephalin-Arg6-Phe7). The heptapeptide was first isolated from chromaffin granule