Zobrazeno 1 - 10
of 194
pro vyhledávání: '"R. J. Flower"'
Publikováno v:
Mediators of Inflammation, Vol 8, Iss 1, Pp 53-62 (1999)
Specific binding sites for the anti-inflammatory protein annexin I have been detected on the surface of human monocytes and polymorphonuclear leukocytes (PMN). These binding sites are proteinaceous in nature and are sensitive to cleavage by the prote
Externí odkaz:
https://doaj.org/article/0f9398d88bdf4f3ca3f31a64e55838f7
Publikováno v:
Mediators of Inflammation, Vol 6, Iss 5-6, Pp 363-367 (1997)
Overnight incubation of human eosinophils (Eøs) with the glucocorticoid hormone dexamethasone (DEX; 0.1 μM) resulted in lower expression of the CD11b, but not CD49d, antigen on their plasma membrane, as assessed by flow cytometry. DEX produced a co
Externí odkaz:
https://doaj.org/article/6d6d7f7d204c449e90721178145e9009
Autor:
R J Flower, Y.S. Bakhle
Publikováno v:
British Journal of Pharmacology. 174:341-342
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7075792a82836a8fe5a897877157ea35
https://doi.org/10.1111/bph.13683
https://doi.org/10.1111/bph.13683
Autor:
R J Flower
Publikováno v:
British Journal of Pharmacology. 147:S182-S192
The formation of the British Pharmacological Society coincided almost exactly with a series of ground-breaking studies that ushered in an entirely new field of research--that of lipid mediator pharmacology. For many years following their chemical cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b682e051a95173deaea6437c22be7916
https://doi.org/10.1038/sj.bjp.0706506
https://doi.org/10.1038/sj.bjp.0706506
Autor:
P G, Trentin, T P T, Ferreira, A C S, Arantes, B T, Ciambarella, R S B, Cordeiro, R J, Flower, M, Perretti, M A, Martins, P M R, Silva
Publikováno v:
British journal of pharmacology. 172(12)
Endogenous glucocorticoids are pro-resolving mediators, an example of which is the endogenous glucocorticoid-regulated protein annexin A1 (ANXA1). Because silicosis is an occupational lung disease characterized by unabated inflammation and fibrosis,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bf62fe7746ab5f7d4a9c0c38f9cd7ae4
https://pubmed.ncbi.nlm.nih.gov/25659822
https://pubmed.ncbi.nlm.nih.gov/25659822
Autor:
Andrew D Beswick, R. J. Flower, Janet Elizabeth Pickering, Peter McCarron, J. R. O'Brien, Peter Creighton Elwood, S. R. Renaud
Publikováno v:
British Journal of Haematology. 113:514-520
A platelet test that is predictive of myocardial infarction (MI) and/or stroke would enable the targeting of anti-platelet drugs towards high-risk patients. The predictive power of several platelet tests for MI and for stroke was examined in 2000 old
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52c3ea0203a8f8f955c42d7f2a3ed2b1
https://doi.org/10.1046/j.1365-2141.2001.02728.x
https://doi.org/10.1046/j.1365-2141.2001.02728.x
Autor:
R. J. Flower
Publikováno v:
Rheumatology. 38:693-696
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::426992198c906447a0b7f05eba1d3575
https://doi.org/10.1093/rheumatology/38.8.693
https://doi.org/10.1093/rheumatology/38.8.693
Publikováno v:
The FASEB Journal. 20:1498-1500
Annexin A1 (ANXA1) has an important role in cell-cell communication in the host defense and neuroendocrine systems. In both systems, its actions are exerted extracellularly via membrane-bound receptors on adjacent sites after translocation of the pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d71e50a765ec1e17fc1565518931a69
https://doi.org/10.1096/fj.05-5319fje
https://doi.org/10.1096/fj.05-5319fje
Publikováno v:
The Journal of Immunology. 159:1466-1473
Cell accumulation in response to i.p. administration of the C-C chemokine, eotaxin, was studied in vivo. OVA-sensitized mice, exhibiting blood eosinophilia, had greater eosinophil (Eø) accumulation in response to 500 ng of eotaxin at 6 h (vehicle-in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7e882c790b46657d58b29ea21b77062
https://doi.org/10.4049/jimmunol.159.3.1466
https://doi.org/10.4049/jimmunol.159.3.1466
Publikováno v:
Journal of Endocrinology. 147:533-544
Glucocorticoids have been shown repeatedly to inhibit the secretion of TSH in experimental animals and in man but their site and mode of action are unknown. In the present study, we have used an in vitro model to examine the effects of dexamethasone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::870aadf0536fe045c9edb6509e317327
https://doi.org/10.1677/joe.0.1470533
https://doi.org/10.1677/joe.0.1470533