Zobrazeno 1 - 10
of 392
pro vyhledávání: '"R. J. Ferrante"'
Publikováno v:
Journal of neurochemistry. 79(6)
Mitochondrial dysfunction and oxidative damage may play a role in the pathogenesis of Huntington's disease (HD). We examined concentrations of 8-hydroxy-2-deoxyguanosine (OH(8)dG), a well-established marker of oxidative damage to DNA, in a transgenic
Autor:
O A, Andreassen, R J, Ferrante, P, Klivenyi, A M, Klein, L A, Shinobu, C J, Epstein, M F, Beal
Publikováno v:
Annals of neurology. 47(4)
The pathogenesis of neuronal cell death as a consequence of mutations in copper/zinc superoxide dismutase (SOD1) associated with familial amyotrophic lateral sclerosis may involve oxidative damage and mitochondrial dysfunction. We examined whether cr
Autor:
S, Kuemmerle, C A, Gutekunst, A M, Klein, X J, Li, S H, Li, M F, Beal, S M, Hersch, R J, Ferrante
Publikováno v:
Annals of neurology. 46(6)
The mechanism by which polyglutamine expansion in Huntington's disease (HD) results in selective neuronal degeneration remains unclear. We previously reported that the immunohistochemical distribution of N-terminal huntingtin in HD does not correspon
Publikováno v:
Journal of neurochemistry. 73(5)
The polyglutamine-expanded N-terminal region of mutant huntingtin causes neurodegeneration in Huntington's disease (HD). Neuronal intranuclear and cytosolic inclusions composed of mutant huntingtin are found in brains of HD patients. Because tissue t
Autor:
E B, Hanlon, I, Itzkan, R R, Dasari, M S, Feld, R J, Ferrante, A C, McKee, D, Lathi, N W, Kowall
Publikováno v:
Photochemistry and photobiology. 70(2)
The purpose of this study was to investigate whether near-infrared (NIR) fluorescence spectroscopy could be used to detect Alzheimer's disease (AD) by brain tissue autofluorescence. Unfixed temporal cortex specimens from AD cases and age-matched, non
Publikováno v:
The Journal of biological chemistry. 273(30)
Huntington's disease (HD) is caused by the expansion of a glutamine repeat in the protein huntingtin. The expanded glutamine repeat is thought to mediate a gain of function by causing huntingtin to abnormally interact with other proteins. We previous
Autor:
Yang, Sheng1,2 (AUTHOR), Qin, Chuan1,2 (AUTHOR), Chen, Man1,2 (AUTHOR), Chu, Yun‐Hui1,2 (AUTHOR), Tang, Yue1,2 (AUTHOR), Zhou, Luo‐Qi1,2 (AUTHOR), Zhang, Hang1,2 (AUTHOR), Dong, Ming‐Hao1,2 (AUTHOR), Pang, Xiao‐Wei1,2 (AUTHOR), Chen, Lian1,2 (AUTHOR), Wu, Long‐Jun3 (AUTHOR), Tian, Dai‐Shi1,2 (AUTHOR) tiands@tjh.tjmu.edu.cn, Wang, Wei1,2 (AUTHOR) wwang@tjh.tjmu.edu.cn
Publikováno v:
Advanced Science. 3/13/2024, Vol. 11 Issue 10, p1-15. 15p.
Publikováno v:
Agents and Actions. 39:C102-C103
Thromboembolic complications have been described in graft recipients receiving cyclosporine (CS). Whether these individuals have a hypercoagulable state when compared to healthy controls was evaluated. Recalcification times (RT) of saline-incubated c
Autor:
Li, Caijuan1,2 (AUTHOR), Lin, Yingqi1,2 (AUTHOR), Chen, Yizhi1 (AUTHOR), Song, Xichen1 (AUTHOR), Zheng, Xiao1 (AUTHOR), Li, Jiawei1 (AUTHOR), He, Jun3 (AUTHOR), Chen, Xiusheng1 (AUTHOR), Huang, Chunhui1 (AUTHOR), Wang, Wei1 (AUTHOR), Wu, Jianhao1 (AUTHOR), Wu, Jiaxi1 (AUTHOR), Gao, Jiale1 (AUTHOR), Tu, Zhuchi1 (AUTHOR), Li, Xiao‐Jiang1 (AUTHOR) xjli33@jnu.edu.cn, Yan, Sen1,2 (AUTHOR) 231yansen@jnu.edu.cn, Li, Shihua1 (AUTHOR) lishihualis@jnu.edu.cn
Publikováno v:
Advanced Science. 11/3/2023, Vol. 10 Issue 31, p1-16. 16p.
Autor:
Wang, Yifan1 (AUTHOR), Hong, Qin2 (AUTHOR), Xia, Yueyue1 (AUTHOR), Zhang, Zhao1 (AUTHOR) zhaozhang@fudan.edu.cn, Wen, Bo1 (AUTHOR) bowen75@fudan.edu.cn
Publikováno v:
Advanced Science. Oct2023, Vol. 10 Issue 28, p1-16. 16p.