Zobrazeno 1 - 10
of 24
pro vyhledávání: '"R. J. Dunn"'
Publikováno v:
Microelectronic Engineering. 85:1314-1317
We present the fabrication of a polyimide microcantilever array with integrated gold piezoresistive strain gauges and a thick SU-8 backing for use as a surface stress sensor. The selected polyimide's low Young's modulus (1.8GPa) theoretically results
Publikováno v:
Journal of Neurocytology. 29:485-497
In the nervous system, Ras signal transduction pathways are involved in cellular differentiation, neuronal survival and synaptic plasticity. These pathways can be modulated by Ras guanyl nucleotide exchange factors (Ras GEFs), which activate Ras prot
Publikováno v:
Proceedings of the National Academy of Sciences. 95:3978-3983
In this study, we demonstrate that: ( i ) injection of an adenovirus (Ad) vector containing the brain-derived neurotrophic factor (BDNF) gene (Ad.BDNF) into the vitreous chamber of adult rats results in selective transgene expression by Müller cells
Publikováno v:
Journal of Neuroscience Research. 41:836-845
The neuregulin proteins (GGF/ARIA/NDF/Heregulin) are pleiotrophic growth and differentiation factors whose receptors, erb-B2, erb-B3, and erb-B4, are members of the epidermal growth factor receptor family of receptor tyrosine kinases. With western bl
Publikováno v:
Journal of Neurobiology. 23:481-490
CNTF (ciliary neurotrophic factor), purified from rabbit sciatic nerves by a relatively simple procedure, is bioactive in tissue culture at low picomolar concentration and appears as a doublet on polyacrylamide gel electrophoresis (PAGE). In these ne
Autor:
Annie Vallée, R. J. Dunn, N.A Dower, Naguib Mechawar, P.M Richardson, P Pierret, James C. Stone
Publikováno v:
Neuroscience. 108(3)
Ras guanyl nucleotide-releasing protein (RasGRP) is a recently discovered Ras guanyl nucleotide exchange factor that is expressed in selected regions of the rodent CNS, with high levels of expression in the hippocampus. Biochemical studies suggest th
Publikováno v:
Journal of neurocytology. 29(7)
In the nervous system, Ras signal transduction pathways are involved in cellular differentiation, neuronal survival and synaptic plasticity. These pathways can be modulated by Ras guanyl nucleotide exchange factors (Ras GEFs), which activate Ras prot
Publikováno v:
The Journal of comparative neurology. 426(3)
The PSD-95 family of membrane-associated guanylate kinase (MAGUK) proteins are involved in the assembly and organization of neurotransmitter receptors at excitatory synapses in the vertebrate nervous system. We have isolated partial cDNAs for five PS
Publikováno v:
The Journal of comparative neurology. 389(1)
We have isolated a partial cDNA for the N-methyl-D-aspartate (NMDA) receptor 1 (NMDAR1) subunit from an Apteronotus leptorhynchus brain cDNA library. The A. leptorhynchus cDNA fragment, which corresponds to nucleotides 135-903 within the 5' region of
Publikováno v:
Molecular pharmacology. 45(5)
The effects of riluzole, a novel neuroprotective drug with anticonvulsant and anti-ischemic properties, were studied on currents carried by cloned rat brain IIA sodium channel alpha subunits expressed in Xenopus oocytes. (i) When the oocytes were hel