Zobrazeno 1 - 3
of 3
pro vyhledávání: '"R. J. Deloskey"'
Autor:
M.C. Schadt, Charles J. Eyermann, Patricia C. Weber, E. E. Huston, Hodge Carl Nicholas, F.A. Lewandowski, D. D. Mccabe, J. L. Duke, R. J. Deloskey, C.-H. Chang, Prabhakar K. Jadhav, Patrick Y.S. Lam, Paul J. Ala
Publikováno v:
Journal of Biological Chemistry. 273:12325-12331
As long as the threat of human immunodeficiency virus (HIV) protease drug resistance still exists, there will be a need for more potent antiretroviral agents. We have therefore determined the crystal structures of HIV-1 protease in complex with six c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::689417b6939bbd16e9df99fb6043cc24
https://doi.org/10.1074/jbc.273.20.12325
https://doi.org/10.1074/jbc.273.20.12325
Autor:
D. D. Mccabe, E. E. Huston, R. J. Deloskey, Ronald M. Klabe, Patrick Y.S. Lam, Hodge Carl Nicholas, C.-H. Chang, C. J. Rizzo, B. D. Korant, Paul J. Ala, J. L. Duke
Publikováno v:
Biochemistry. 36(7)
In cell cultures, the key residues associated with HIV-1 resistance to cyclic urea-based HIV-1 protease (PR) inhibitors are Val82 and Ile84 of HIV-1 PR. To gain an understanding of how these two residues modulate inhibitor binding, we have measured t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5d7d9e24ba0290f1b74106b55ed3344
https://pubmed.ncbi.nlm.nih.gov/9048541
https://pubmed.ncbi.nlm.nih.gov/9048541
Publikováno v:
Archives of biochemistry and biophysics. 311(1)
A refolding and purification method for economically producing large quantities of H-ras isolated from Escherichia coli inclusion bodies is described. Experiments were performed to optimize the yield of refolded H-ras for structural analysis by NMR s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::623336c7fe69f67147d47912f09996cc
https://pubmed.ncbi.nlm.nih.gov/8185322
https://pubmed.ncbi.nlm.nih.gov/8185322