Zobrazeno 1 - 10
of 57
pro vyhledávání: '"R. J. Bridges"'
Autor:
M, Nehser, J, Dark, D, Schweitzer, M, Campbell, J, Zwicker, D M, Hitt, H, Little, A, Diaz-Correa, D C, Holley, S A, Patel, C M, Thompson, R J, Bridges
Publikováno v:
Neurochemical research. 45(6)
The cystine/glutamate antiporter system X
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2bbcf3a05dadb10ea185142e13a7b437
https://pubmed.ncbi.nlm.nih.gov/31754956
https://pubmed.ncbi.nlm.nih.gov/31754956
Publikováno v:
Neurochemistry international. 73
The system xc(-) antiporter is a plasma membrane transporter that mediates the exchange of extracellular l-cystine with intracellular l-glutamate. This exchange is significant within the context of the CNS because the import of l-cystine is required
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::574300e2bd1cdd564b824732c81df2d0
https://pubmed.ncbi.nlm.nih.gov/24333322
https://pubmed.ncbi.nlm.nih.gov/24333322
Publikováno v:
The Journal of General Physiology
The cystic fibrosis gene product (CFTR) is a chloride channel which, once phosphorylated, is regulated by nucleotide phosphates (Anderson, M. P., and M. J. Welsh. 1992. Science. 257:1701-1704; Venglarik, C. J., B. D. Schultz, R. A. Frizzell, and R. J
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06d910d7f8fed1814ab73b179fa7fc23
https://doi.org/10.1085/jgp.105.3.329
https://doi.org/10.1085/jgp.105.3.329
Publikováno v:
The Journal of General Physiology
The cystic fibrosis gene product cystic fibrosis transmembrane conductance regulator (CFTR) is a low conductance, cAMP-regulated Cl- channel. Removal of cytosolic ATP causes a cessation of cAMP-dependent kinase-phosphorylated CFTR channel activity th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c403dda59b754f1f50ee9237b50f83f
https://doi.org/10.1085/jgp.104.1.123
https://doi.org/10.1085/jgp.104.1.123
Publikováno v:
Journal of Biological Chemistry. 269:8296-8302
Cystic fibrosis results from mutations in the gene encoding the CFTR Cl- channel. Although CFTR occurs as an integral component of the plasma membrane, recent studies implicate CFTR in endocytic recycling and suggest that the protein may also exist i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6f6032f83a4e2ff73fce49cfedeef4a
https://doi.org/10.1016/s0021-9258(17)37192-2
https://doi.org/10.1016/s0021-9258(17)37192-2
Publikováno v:
The Journal of General Physiology
Outwardly rectifying 30-50-pS Cl- channels mediate cell volume regulation and transepithelial transport. Several recent reports indicate that rectifying Cl- channels are blocked after addition of ATP to the extracellular bath (Alton, E. W. F. W., S.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af8ac97861ee7eca884f541184dbe3bf
http://europepmc.org/articles/PMC2216774
http://europepmc.org/articles/PMC2216774
Autor:
R. J. Bridges, Neil A. Bradbury
Publikováno v:
Biochemical and Biophysical Research Communications. 184:1173-1180
Endocytosis in the chloride secreting epithelial cell line T84 was monitored by uptake of the fluid-phase markers FITC-dextran and horseradish peroxidase (HRP). Uptake of marker was inhibited by incubation of cells at 4 degrees C, consistent with an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b2a06af35a59c0f5376638e8bc395a2
https://doi.org/10.1016/s0006-291x(05)80006-3
https://doi.org/10.1016/s0006-291x(05)80006-3
Publikováno v:
American Journal of Physiology-Cell Physiology. 262:C752-C759
The colonic epithelial cell line T84 has been shown to be a good model to investigate the regulation of Cl- secretion by the adenosine 3',5'-cyclic monophosphate (cAMP)-mediated second messenger cascade. Regulated exocytic insertion and endocytic ret
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19991a426b7e604b8865b486583101bc
https://doi.org/10.1152/ajpcell.1992.262.3.c752
https://doi.org/10.1152/ajpcell.1992.262.3.c752
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1104:87-94
Peroxynitrite (ONOO-) is a potent oxidizing agent that initiates lipid peroxidation and sulfhydryl oxidation and may be responsible for a portion of the cytotoxicity attributed to superoxide anion (.O2-). We quantified the extent to which ONOO-, xant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdfa87be8c5061a990275d58b7bcd44c
https://doi.org/10.1016/0005-2736(92)90135-9
https://doi.org/10.1016/0005-2736(92)90135-9
Autor:
Christine E. Bear, R. J. Bridges, John R. Riordan, Tim J. Jensen, Mohabir Ramjeesingh, Norbert Kartner, Canhui Li
Publikováno v:
Cell. 68:809-818
Circumstantial evidence has accumulated suggesting that CFTR is a regulated low-conductance Cl- channel. To test this postulate directly, we have purified to homogeneity a recombinant CFTR protein from a high-level baculovirus-infected insect cell li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b64f50aae93c660a8c1cc7738f33197
https://doi.org/10.1016/0092-8674(92)90155-6
https://doi.org/10.1016/0092-8674(92)90155-6