Zobrazeno 1 - 6
of 6
pro vyhledávání: '"R. J. Beedham"'
Publikováno v:
Aerobiologia. 26:301-309
Innocuous organisms able to simulate the properties of pathogens are necessary so that the behaviour of pathogenic microorganisms in the environment may be understood. This is essential if we are to understand the epidemiology and consequence managem
Autor:
R.R. Taylor, M.S. Lever, R. J. Beedham, J. Steward, P. Russell, T. J. G. Brooks, Anthony J. Stagg
Publikováno v:
International Journal of Antimicrobial Agents. 24:609-612
The efficacies of prophylactic and therapeutic gatifloxacin and moxifloxacin were assessed in a BALB/c mouse model of systemic and pneumonic plague and compared with ciprofloxacin. Mice were given 100 mg/kg of the antibiotic by oral administration tw
Publikováno v:
Journal of Applied Microbiology. 87:315-317
Protective antigen (PA), the major protective component of the existing vaccine, is a potent immunogen. Protective antigen in alhydrogel induced a high serum IgG titre (> log10 4) in both the C57B16 and Balb/c mouse and the predominant subclass of an
Autor:
M. Stephen Lever, Graham Hall, Richard W. Titball, Anthony J. Stagg, Philip I. Ireland, R. J. Beedham, Michelle Nelson, Georgina Knight
Publikováno v:
Journal of medical microbiology. 52(Pt 12)
The object of this study was to develop and characterize experimental Burkholderia mallei aerosol infection in BALB/c mice. Sixty-five mice were infected with 5000 [approx. 2.5 median lethal doses (MLD)] B. mallei strain ATCC 23344(T) bacteria by the
Autor:
Richard Hebdon, Tony J. Stagg, Jim E. Eyles, H. Oya Alpar, R. J. Beedham, Les Baillie, Helen C. Flick-Smith, E. Diane Williamson, Julie Miller, Emma L. Waters
Publikováno v:
Infection and immunity. 70(4)
Existing licensed anthrax vaccines are administered parenterally and require multiple doses to induce protective immunity. This requires trained personnel and is not the optimum route for stimulating a mucosal immune response. Microencapsulation of v
Autor:
R. J. Beedham, P. Russell, Michael Green, S. M. Eley, Anthony J. Stagg, D Whittington, D. L. Bell, Rosa R. Taylor, D. Rogers, Michelle Nelson, Richard W. Titball
Publikováno v:
The Journal of antimicrobial chemotherapy. 41(2)
The efficacies of ciprofloxacin and doxycycline prophylaxis and therapy were assessed against experimental pneumonic plague infections induced by two strains of Yersinia pestis in a mouse model. When exposed to an aerosol of Y. pestis strain GB, cont