Zobrazeno 1 - 10
of 36
pro vyhledávání: '"R. J. Albertini"'
Autor:
K. Savela, R. R. Perera, Regina M. Santella, Wei-Yann Tsai, J. P. O'neill, K. Hemminki, LaVerne A. Mooney, R. J. Albertini, Ruth Ottman, Chris Dickey
Publikováno v:
Carcinogenesis. 15:2905-2910
Carcinogen-DNA adducts and somatic gene mutation at the hypoxanthine guanine phosphoribosyl transferase (HPRT) locus were evaluated in peripheral leukocytes of workers in an iron foundry with exposure to benzo[a]pyrene (B[a]P) and other polycyclic ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a424fea0d1122b81ca5c66efc0e8944
https://doi.org/10.1093/carcin/15.12.2905
https://doi.org/10.1093/carcin/15.12.2905
Autor:
Wei-Yann Tsai, Ruth Ottman, J. P. O'neill, F.P. Perera, Regina M. Santella, Kari Hemminki, Deliang Tang, K. Savela, Chris Dickey, W. L. Bigbee, LaVerne A. Mooney, R. J. Albertini
Publikováno v:
Carcinogenesis. 14:969-973
Mutations were evaluated in workers in an iron foundry with exposure to polycyclic aromatic hydrocarbons (PAHs), measured by personal and area monitoring, ranging from < 5 to 60 ng/m3 of benzo[a]pyrene (B[a]P). Mutation at the hypoxanthine guanine ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3b4cf3344aea446f0b31447db5b8c34
https://doi.org/10.1093/carcin/14.5.969
https://doi.org/10.1093/carcin/14.5.969
Autor:
R. J. Albertini
Publikováno v:
Radiation protection dosimetry. 97(1)
There is currently a vast armamentarium of biomarkers for evaluating human exposures to environmental carcinogens, the effects of such exposures and/or susceptibility to disease outcome. Before application, however, these biomarkers require validatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff490f637059150b487c513fdb02ba51
https://pubmed.ncbi.nlm.nih.gov/11763357
https://pubmed.ncbi.nlm.nih.gov/11763357
Autor:
R. J. Albertini
This research project will determine the T-cell receptor (TCR) gene usages of beryllium reactive T-lymphocytes isolated directly from the peripheral blood of individuals exposed at a U.S. Department of Energy site. The objective is to develop a sensi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d221b7fef82dd6a252930a64861c22d
https://doi.org/10.2172/783573
https://doi.org/10.2172/783573
Autor:
R J, Albertini, D, Anderson, G R, Douglas, L, Hagmar, K, Hemminki, F, Merlo, A T, Natarajan, H, Norppa, D E, Shuker, R, Tice, M D, Waters, A, Aitio
Publikováno v:
Mutation research. 463(2)
The purpose of these guidelines is to provide concise guidance on the planning, performing and interpretation of studies to monitor groups or individuals exposed to genotoxic agents. Most human carcinogens are genotoxic but not all genotoxic agents h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4075744e7e2ee1b840de2a734a10810a
https://pubmed.ncbi.nlm.nih.gov/10913908
https://pubmed.ncbi.nlm.nih.gov/10913908
Autor:
R J, Albertini
Publikováno v:
Biotherapy (Dordrecht, Netherlands). 11(2-3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a293a7d7743812ea4830f1f573c43843
https://pubmed.ncbi.nlm.nih.gov/9677047
https://pubmed.ncbi.nlm.nih.gov/9677047
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 6(12)
Aminothiols, such as WR-2721 and its active free thiol, WR-1065, reduce mutations from ionizing radiation in exponentially growing cells. In this study, human noncycling G0 T lymphocytes were exposed in vitro to gamma-irradiation in the presence or a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0d7c0d06e8bb7818b142ba7ad5378a83
https://pubmed.ncbi.nlm.nih.gov/9419399
https://pubmed.ncbi.nlm.nih.gov/9419399
Publikováno v:
Radiation research. 148
Human T lymphocytes can be used to determine the frequency and molecular spectrum of somatic cell gene mutations induced by ionizing radiations both in vivo and in vitro. In vitro exposure of these G0 cells to low-LET 137Cs gamma rays results in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9636925ff27c1649b89029d60bfd1709
https://pubmed.ncbi.nlm.nih.gov/9355860
https://pubmed.ncbi.nlm.nih.gov/9355860
Autor:
P K, Gupta, A, Sahota, S A, Boyadjiev, S, Bye, C, Shao, J P, O'Neill, T C, Hunter, R J, Albertini, P J, Stambrook, J A, Tischfield
Publikováno v:
Cancer research. 57(6)
We have used the adenine phosphoribosyltransferase gene (APRT; 16q24) to investigate the mechanisms of loss of heterozygosity (LOH) in normal human somatic cells in vivo. APRT-deficient (APRT-/-, APRT-/0) T lymphocytes from the peripheral blood of fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e1b5dc1ad5437ca7256a826a60d53c73
https://pubmed.ncbi.nlm.nih.gov/9067291
https://pubmed.ncbi.nlm.nih.gov/9067291
Autor:
R J, Albertini, R B, Hayes
Publikováno v:
IARC scientific publications. (142)
Somatic cell mutations arising in vivo in reporter genes and in cancer-associated genes may now be measured in humans. Background mutation levels and mutational responses following various mutagen exposures are reviewed in this chapter. The detection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ac8ae85cd133ba8bca1170aec7479044
https://pubmed.ncbi.nlm.nih.gov/9354918
https://pubmed.ncbi.nlm.nih.gov/9354918