Zobrazeno 1 - 10
of 56
pro vyhledávání: '"R. I. Goncharova"'
Publikováno v:
Вавиловский журнал генетики и селекции, Vol 19, Iss 5, Pp 638-646 (2015)
HRAS, KRAS and NRAS gene products belong to the superfamily of small GTPases. These proteins regulate cellular response to extracellular stimuli by means of activation of different signaling pathways. Although the role of RAS gene mutations in the pa
Externí odkaz:
https://doaj.org/article/23700143d88c48cf8511ae3c37040b6d
Publikováno v:
Doklady of the National Academy of Sciences of Belarus. 66:614-621
The growth factor genes VEGF and TGFB1 are involved in the normal functioning of the kidneys, and some polymorphic loci of these genes determine a genetic predisposition to the autoimmune diseases, including systemic lupus erythematosus (SLE) and its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2bde8eef05a93f722ee2a918b24dd753
https://doi.org/10.29235/1561-8323-2022-66-6-614-621
https://doi.org/10.29235/1561-8323-2022-66-6-614-621
Autor:
Telat Yanik, R. I. Goncharova, Murat Arslan, Seyda Tacer-Tanas, Fatih Korkmaz, Aliaksandr Slukvin, Mustafa Erat
Publikováno v:
Journal of Applied Ichthyology. 37:942-949
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76576d73469009bab35f0843d100057a
https://doi.org/10.1111/jai.14247
https://doi.org/10.1111/jai.14247
Publikováno v:
Молекулярная и прикладная генетика. 30:14-24
A cohort of 287 patients with rheumatoid arthritis (RA) showed that molecular variants (minor T allele and homozygous TT genotype) of the STAT4 rs7574865 polymorphic locus increase the risk of RA development and impact the clinical characteristics of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74541367a1d9112b5a0e0f030229ff9d
https://doi.org/10.47612/1999-9127-2021-30-14-24
https://doi.org/10.47612/1999-9127-2021-30-14-24
Autor:
R. I. Goncharova, N. V. Savina, I. A. Kazyra, A. G. Bialkevich, A. V. Sukalo, N. V. Nikitchenko
Publikováno v:
Medical Journal. :49-55
The study of the molecular and genetic nature of inherited kidney diseases is relevant in modern nephrology. It allows us to establish the etiology, develop new methods of treatment and prevention. The aim of the research was to study the genetic pol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::339a4d77257945d2c39e34e145bad3ba
https://doi.org/10.51922/1818-426x.2021.2.49
https://doi.org/10.51922/1818-426x.2021.2.49
Autor:
M P Smal, Elizaveta O. Boldinova, R I Goncharova, Alena V. Makarova, A. D. Stolyarenko, Rafil Khairullin, R N Chuprov-Netochin, Evgeniy S. Shilkin
Publikováno v:
Biochemistry (Moscow). 85:425-435
Tens of thousands of DNA lesions are formed in mammalian cells each day. DNA translesion synthesis is the main mechanism of cell defense against unrepaired DNA lesions. DNA polymerases iota (Pol ι), eta (Pol η), kappa (Pol κ), and zeta (Pol ζ) ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::320bc0de0531d8caf15d1f00f6186b39
https://doi.org/10.1134/s0006297920040033
https://doi.org/10.1134/s0006297920040033
Autor:
H. A. Yatskiu, Nataliya V. Nikitchenko, R. I. Goncharova, Alexander V. Sukalo, Tatyana D. Kuzhir, A. M. Tchitchko, Nataliya V. Savina
Publikováno v:
Ecological genetics. 17:65-76
Background. GWASs revealed a huge amount of candidate genes for juvenile idiopathic arthritis (JIA) susceptibility. Individual SNP analysis has restrictions as an effect of each substitution may be too subtle to be detected but their interactions may
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d495f5fe0177711e0d8de2ca1bb2731b
https://doi.org/10.17816/ecogen17465-76
https://doi.org/10.17816/ecogen17465-76
Publikováno v:
Faktori eksperimental'noi evolucii organizmiv. 24:233-238
Aim. To determine the influence of the polymorphic variants of the base (OGG1 and XRCC1) and nucleotide (ERRC2/XPD and ERRC6/CSB) excision repair genes on the mutational and epigenetic status of bladder tumors. Methods. For this study, we used previo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::452c0259d9830f6b67b24dbbbfebd650
https://doi.org/10.7124/feeo.v24.1107
https://doi.org/10.7124/feeo.v24.1107
Autor:
A. V. Sukalo, N. V. Nikitchenko, R. I. Goncharova, Ina Kazyra, Hanna Bialkevich, Anna Krylova-Alefirenko
Publikováno v:
Nephrology Dialysis Transplantation. 36
Background and Aims Previously it was shown that significantly elevated serum concentration of vascular-endothelial growth factor (VEGF) and transforming growth factor β (TGF-β1) is observed in Lupus Nephritis (LN) patients, especially in those wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6e05047e2094b01000d149e7c3b8df8
https://doi.org/10.1093/ndt/gfab108.0016
https://doi.org/10.1093/ndt/gfab108.0016
Autor:
A. D. Stolyarenko, Elizaveta O. Boldinova, Evgeniy S. Shilkin, R I Goncharova, M P Smal, Alena V. Makarova, R N Chuprov-Netochin
Publikováno v:
Biochemistry. Biokhimiia. 85(8)
Many chemotherapy drugs block tumor cell division by damaging DNA. DNA polymerases eta (Pol η), iota (Pol ι), kappa (Pol κ), REV1 of the Y-family and zeta (Pol ζ) of the B-family efficiently incorporate nucleotides opposite a number of DNA lesion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6394d5e179a4e916b6b2be16750c396
https://pubmed.ncbi.nlm.nih.gov/33045948
https://pubmed.ncbi.nlm.nih.gov/33045948