Zobrazeno 1 - 10
of 140
pro vyhledávání: '"R. Hsiung"'
Autor:
Khushbu J. Patel, David Yang, John R. Best, Colleen Chambers, Philip E. Lee, Alexandre Henri‐Bhargava, Clark R. Funnell, Dean J. Foti, Jacqueline A. Pettersen, Howard H. Feldman, Haakon B. Nygaard, Ging‐Yuek R. Hsiung, Mari L. DeMarco
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 10, Iss 2, Pp n/a-n/a (2024)
Abstract INTRODUCTION In the Investigating the Impact of Alzheimer's Disease Diagnostics in British Columbia (IMPACT‐AD BC) study, we aimed to understand how Alzheimer's disease (AD) cerebrospinal fluid (CSF) biomarker testing—used in medical car
Externí odkaz:
https://doaj.org/article/0b3ef9451f9848b3a2c74e5b3e057d1f
Autor:
Khushbu J. Patel, David Yang, Howard H. Feldman, Ging‐Yuek R. Hsiung, Haakon B. Nygaard, John R. Best, Emily Dwosh, Julie M. Robillard, Mari L. DeMarco
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 10, Iss 2, Pp n/a-n/a (2024)
Abstract INTRODUCTION We described patients’ and care partners’ experiences with Alzheimer's disease (AD) cerebrospinal fluid (CSF) biomarker testing and result disclosure in routine care. METHODS IMPACT‐AD BC is an observational study of clini
Externí odkaz:
https://doaj.org/article/9621bc82cc234204941cd46af4cac87f
Autor:
Teresa Liu-Ambrose, Elizabeth Dao, Rachel A. Crockett, Cindy K. Barha, Ryan S. Falck, John R. Best, Ging-Yeuk R. Hsiung, Thalia S. Field, Kenneth M. Madden, Walid A. Alkeridy, Narlon C. Boa Sorte Silva, Jennifer C. Davis, Lisanne F. ten Brinke, Stephanie Doherty, Roger C. Tam
Publikováno v:
Trials, Vol 22, Iss 1, Pp 1-12 (2021)
Abstract Background Subcortical ischemic vascular cognitive impairment (SIVCI) is the most common form of vascular cognitive impairment. Importantly, SIVCI is considered the most treatable form of cognitive impairment in older adults, due to its modi
Externí odkaz:
https://doaj.org/article/1c3b122363624e78b172cdc4515277d5
Autor:
Yi Su, Shaney Flores, Guoqiao Wang, Russ C. Hornbeck, Benjamin Speidel, Nelly Joseph‐Mathurin, Andrei G. Vlassenko, Brian A. Gordon, Robert A. Koeppe, William E. Klunk, Clifford R. Jack Jr., Martin R. Farlow, Stephen Salloway, Barbara J. Snider, Sarah B. Berman, Erik D. Roberson, Jared Brosch, Ivonne Jimenez‐Velazques, Christopher H. vanDyck, Douglas Galasko, Shauna H. Yuan, Suman Jayadev, Lawrence S. Honig, Serge Gauthier, Ging‐Yuek R. Hsiung, Mario Masellis, William S. Brooks, Michael Fulham, Roger Clarnette, Colin L. Masters, David Wallon, Didier Hannequin, Bruno Dubois, Jeremie Pariente, Raquel Sanchez‐Valle, Catherine Mummery, John M. Ringman, Michel Bottlaender, Gregory Klein, Smiljana Milosavljevic‐Ristic, Eric McDade, Chengjie Xiong, John C. Morris, Randall J. Bateman, Tammie L.S. Benzinger
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 11, Iss 1, Pp 180-190 (2019)
Abstract Introduction Quantitative in vivo measurement of brain amyloid burden is important for both research and clinical purposes. However, the existence of multiple imaging tracers presents challenges to the interpretation of such measurements. Th
Externí odkaz:
https://doaj.org/article/6e1734993f954447b3409ef075057895
Autor:
Karteek Popuri, Mirza Faisal Beg, Hyunwoo Lee, Rakesh Balachandar, Lei Wang, Vesna Sossi, Claudia Jacova, Matt Baker, Elham Shahinfard, Rosa Rademakers, Ian R.A. Mackenzie, Ging-Yuek R. Hsiung
Publikováno v:
NeuroImage: Clinical, Vol 31, Iss , Pp 102687- (2021)
Objective: Our aim is to investigate patterns of brain glucose metabolism using fluorodeoxyglucose positron emission tomography (FDG-PET) in presymptomatic carriers of the C9orf72 repeat expansion to better understand the early preclinical stages of
Externí odkaz:
https://doaj.org/article/4e068226b77a4abea6cd627065276f3b
Autor:
Sieun Lee, Kailun Jiang, Brandon McIlmoyle, Eleanor To, Qinyuan (Alis) Xu, Veronica Hirsch-Reinshagen, Ian R. Mackenzie, Ging-Yuek R. Hsiung, Brennan D. Eadie, Marinko V. Sarunic, Mirza Faisal Beg, Jing Z. Cui, Joanne A. Matsubara
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Alzheimer’s disease (AD) is the most prevalent form of dementia, accounting for 60–70% of all dementias. AD is often under-diagnosed and recognized only at a later, more advanced stage, and this delay in diagnosis has been suggested as a contribu
Externí odkaz:
https://doaj.org/article/215fa0d53a1740628040aebabed8db97
Autor:
Karteek Popuri, Emma Dowds, Mirza Faisal Beg, Rakesh Balachandar, Mahadev Bhalla, Claudia Jacova, Adrienne Buller, Penny Slack, Pheth Sengdy, Rosa Rademakers, Dana Wittenberg, Howard H. Feldman, Ian R. Mackenzie, Ging-Yuek R. Hsiung
Publikováno v:
NeuroImage: Clinical, Vol 18, Iss , Pp 591-598 (2018)
Frontotemporal dementia (FTD) is a neurodegenerative disease with a strong genetic basis. Understanding the structural brain changes during pre-symptomatic stages may allow for earlier diagnosis of patients suffering from FTD; therefore, we investiga
Externí odkaz:
https://doaj.org/article/d42d34fa28bb48d399ec91c61c24892c
Autor:
Veronica Hirsch-Reinshagen, Cyril Pottier, Alexandra M. Nicholson, Matt Baker, Ging-Yuek R. Hsiung, Charles Krieger, Pheth Sengdy, Kevin B. Boylan, Dennis W. Dickson, Marsel Mesulam, Sandra Weintraub, Eileen Bigio, Lorne Zinman, Julia Keith, Ekaterina Rogaeva, Sasha A. Zivkovic, David Lacomis, J. Paul Taylor, Rosa Rademakers, Ian R. A. Mackenzie
Publikováno v:
Acta Neuropathologica Communications, Vol 5, Iss 1, Pp 1-13 (2017)
Abstract Mutations in the stress granule protein T-cell restricted intracellular antigen 1 (TIA1) were recently shown to cause amyotrophic lateral sclerosis (ALS) with or without frontotemporal dementia (FTD). Here, we provide detailed clinical and n
Externí odkaz:
https://doaj.org/article/e0d91199d2474d74ba7a17e9667fb08b
Autor:
Manuela Neumann, Jolien Perneel, Simon Cheung, Marleen Van den Broeck, Haakon Nygaard, Ging-Yuek R. Hsiung, Sarah Wynants, Bavo Heeman, Rosa Rademakers, Ian R. A. Mackenzie
Publikováno v:
Acta neuropathologica 146(1), 163-166 (2023). doi:10.1007/s00401-023-02580-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86f1946e673b8e1cae3e02a378bc5ff1
https://doi.org/10.1007/s00401-023-02580-2
https://doi.org/10.1007/s00401-023-02580-2
Autor:
Lisanne F. ten Brinke, Ging-Yuek R Hsiung, Youngjin Yoo, Alex L. MacKay, Teresa Liu-Ambrose, Elizabeth Dao, Rachel A. Crockett, Stephanie Doherty, Roger Tam, Cindy K. Barha, Walid Al Keridy, Cornelia Laule
Publikováno v:
Journal of Alzheimer's Disease. 80:91-101
Background: Myelin damage is a salient feature in cerebral small vessel disease (cSVD). Of note, myelin damage extends into the normal appearing white matter (NAWM). Currently, the specific role of myelin content in cognition is poorly understood. Ob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92e2756528abc2e3cbaf0d7954846720
https://doi.org/10.3233/jad-201134
https://doi.org/10.3233/jad-201134