Zobrazeno 1 - 10
of 171
pro vyhledávání: '"R. Honegger"'
Autor:
Jonathan R. Honegger, Charitha Gowda
Publikováno v:
Current opinion in infectious diseases. 35(5)
Direct-acting antiviral (DAA) regimens targeting hepatitis C virus (HCV) are now approved for young children. This review examines recent DAA experience in children, current treatment recommendations and challenges, and potential treatment-as-prevent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc85f8df7abb025689a5e448c3c24024
https://pubmed.ncbi.nlm.nih.gov/35852787
https://pubmed.ncbi.nlm.nih.gov/35852787
Publikováno v:
Viruses, Vol 13, Iss 7, p 1351 (2021)
Thirty years after its discovery, the hepatitis C virus (HCV) remains a leading cause of liver disease worldwide. Given that many countries continue to experience high rates of transmission despite the availability of potent antiviral therapies, an e
Externí odkaz:
https://doaj.org/article/0670a10867c94be7b6a7e7ff5d2c33ab
Autor:
Arash Grakoui, Samantha L. Coss, Christopher M. Walker, Jonathan R. Honegger, Almudena Torres-Cornejo, Georg M. Lauer, Mona Prasad, Melissa Moore-Clingenpeel
Publikováno v:
Journal of Clinical Investigation. 130:748-753
Chronic hepatitis C virus (HCV) infection is characterized by persistent high-level viremia and defective cellular immunity, including a lack of functional HCV-specific CD4+ T cells. We previously described an exceptional period of viral control that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d14cbb926a80a568f26cf3544e01bc97
https://doi.org/10.1172/jci123623
https://doi.org/10.1172/jci123623
Publikováno v:
The Journal of Immunology. 208:126.42-126.42
Chronic hepatitis C virus (HCV) infection is characterized by dysfunctional HCV-specific CD8+ T cells, rare CD4+ T responses, and stable high-level viremia. Recovered CD4+ T cell function and unusual declines in viremia have been observed in some wom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5654238d8cea2c880584d885afc28a0f
https://doi.org/10.4049/jimmunol.208.supp.126.42
https://doi.org/10.4049/jimmunol.208.supp.126.42
Autor:
Asuncion Mejias, Mark E. Peeples, Roshini S. Abraham, W. Garrett Hunt, Peter J. Mustillo, Masako Shimamura, Joanna M. Marshall, Cesar M. Rueda, Will Guider, Sergio D. Rosenzweig, Claire Stewart, Hye Sun Kuehn, Monica I Ardura, Jonathan R. Honegger, Octavio Ramilo, Sophonie Jean, Tiffany King, Huanyu Wang, Amber Gibbs
Publikováno v:
The Journal of Allergy and Clinical Immunology
Journal of Allergy and Clinical Immunology
Journal of Allergy and Clinical Immunology
Background SARS-CoV-2 is a novel coronavirus that emerged recently and has created a global pandemic. Symptomatic SARS-CoV-2 infection, termed Coronavirus disease 2019 (COVID-19), has been associated with a host of symptoms affecting numerous organ s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c6b3097811463d181d267054d0158d0
http://europepmc.org/articles/PMC7525247
http://europepmc.org/articles/PMC7525247
Autor:
Katherine Moyer, Stephanie Smith, Charitha Gowda, Linda Crim, Pablo J. Sánchez, Jonathan R. Honegger
Publikováno v:
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 73(9)
Background Most US children with perinatal hepatitis C virus (HCV) exposure fail to receive the recommended anti-HCV antibody test at age ≥18 months. Earlier testing for viral RNA might facilitate increased screening, but sensitivity of this approa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c046412c18ed28d3e60c363efcefef4
https://pubmed.ncbi.nlm.nih.gov/32640029
https://pubmed.ncbi.nlm.nih.gov/32640029
Publikováno v:
The Journal of Immunology. 206:103.17-103.17
Chronic hepatitis C virus (HCV) infection is marked by a loss of HCV-specific CD4+ T cells and CD8+ T cell exhaustion. However, recovery of antiviral CD4+ T cells and decreased viremia occurs in some women after pregnancy. We hypothesize that recover
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d01598a45eaccc531ec5c22abc20d40
https://doi.org/10.4049/jimmunol.206.supp.103.17
https://doi.org/10.4049/jimmunol.206.supp.103.17
Publikováno v:
Cold Spring Harb Perspect Med
Approximately 70% of acute hepatitis C virus (HCV) infections become chronic, indicating that the virus is exceptionally well adapted to persist in humans with otherwise normal immune function. Robust, lifelong replication of this small RNA virus doe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b9c7f41311c71ff1d4c4d9575bb9ac3
https://doi.org/10.1101/cshperspect.a036954
https://doi.org/10.1101/cshperspect.a036954
Autor:
Ling Wang, Samuel Kennedy, Mona Prasad, Catherine Glover, Jonathan R. Honegger, Charitha Gowda
Background Hepatitis C virus (HCV) infection is under-recognized among US adults and children. Prenatal HCV screening may help close the diagnosis gap among women while also identifying at-risk infants. Current surveillance efforts for maternal HCV r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5e07285247e1b3638f2ae6c2d6fbfa1
https://europepmc.org/articles/PMC6512319/
https://europepmc.org/articles/PMC6512319/
Autor:
Jonathan R. Honegger
Publikováno v:
Oxford Medicine
An estimated 185 million individuals have been infected with hepatitis C virus (HCV) worldwide. Although often clinically silent for decades, chronic HCV infection predisposes to late-onset complications, including liver cirrhosis and hepatocellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0f489ed831c8e0fc790bbe7b92135f7
https://doi.org/10.1093/med/9780190604813.003.0005
https://doi.org/10.1093/med/9780190604813.003.0005