Zobrazeno 1 - 10
of 4 235
pro vyhledávání: '"R. Hayes"'
Autor:
K. Sabapathy, L. Balzer, J. Larmarange, L. Block, S. Floyd, C. Iwuji, K. Wirth, H. Ayles, S. Fidler, M. Kamya, M. Petersen, D. Havlir, F. Dabis, J. Moore, R. Hayes
Publikováno v:
BMC Public Health, Vol 22, Iss 1, Pp 1-16 (2022)
Abstract Background Four large community-randomized trials examining universal testing and treatment (UTT) to reduce HIV transmission were conducted between 2012–2018 in Botswana, Kenya, Uganda, Zambia and South Africa. In 2014, the UNAIDS 90–90-
Externí odkaz:
https://doaj.org/article/b3a58864f6c14f2aa317948ce0282415
Autor:
N. F. Bell-Mandla, R. Sloot, G. Maarman, S. Griffith, A. Moore, S. Floyd, R. Hayes, S. Fidler, H. Ayles, P. Bock, on behalf of the HPTN 071 (PopART) study team
Publikováno v:
BMC Medical Research Methodology, Vol 21, Iss 1, Pp 1-8 (2021)
Abstract Background Identifying successful strategies to improve participant retention in longitudinal studies remains a challenge. In this study we evaluated whether non-traditional fieldworker shifts (after hours during the week and weekends) enhan
Externí odkaz:
https://doaj.org/article/bee62039dbdb46989781259d6720c0d4
Autor:
D. Fonseca De Freitas, I. Patel, G. Kadra-Scalzo, M. Pritchard, H. Shetty, M. Broadbent, R. Patel, J. Downs, A. Segev, M. Khondoker, J. Maccabe, K. Bhui, R. Hayes
Publikováno v:
European Psychiatry, Vol 65, Pp S611-S611 (2022)
Introduction Ethnic disparities in treatment with clozapine, the antipsychotic recommended for treatment-resistant schizophrenia (TRS), have been reported. However, these investigations frequently suffer from potential residual confounding. For examp
Externí odkaz:
https://doaj.org/article/5760368d4b4340fa85bf33e2884e42b7
Publikováno v:
European Psychiatry, Vol 65, Pp S340-S340 (2022)
Introduction Studies have shown ethnic inequalities in health, with a higher incidence of illnesses among people of some minoritised ethnic groups. Furthermore, it has been observed that people with severe mental illnesses have a higher risk for mult
Externí odkaz:
https://doaj.org/article/3d38aa68911f4c4da09eb7066d73f522
Autor:
D. Fonseca De Freitas, D. Agbedjro, G. Kadra-Scalzo, E. Francis, I. Ridler, M. Pritchard, H. Shetty, A. Segev, C. Casetta, S. Smart, A. Morris, J. Downs, S. Christensen, N. Bak, B. Kinon, D. Stahl, R. Hayes, J. Maccabe
Publikováno v:
European Psychiatry, Vol 65, Pp S781-S782 (2022)
Introduction There is emerging evidence of heterogeneity within treatment-resistance schizophrenia (TRS), with some people not responding to antipsychotic treatment from illness onset and a smaller group becoming treatment-resistant after an initial
Externí odkaz:
https://doaj.org/article/916ac615cc7a4d1c80343f931f8eb44c
Autor:
K.R. Mitchell, T. Erio, H.S. Whitworth, G. Marwerwe, J. Changalucha, K. Baisley, C.J. Lacey, R. Hayes, S. de SanJosé, D. Watson-Jones
Publikováno v:
Tumour Virus Research, Vol 12, Iss , Pp 200217- (2021)
ABSTRACT (198): Background: The multi-dose regimen is a known barrier to successful human papillomavirus (HPV) vaccination. Emerging evidence suggests that one vaccine dose could protect against HPV. While there are clear advantages to a single dose
Externí odkaz:
https://doaj.org/article/cd1621b57d6d40338b060f6ad6f62bd8
Autor:
Rogger P. Carmen-Orozco, William Tsao, Yingzhi Ye, Irika R. Sinha, Koping Chang, Vickie T. Trinh, William Chung, Kyra Bowden, Juan C. Troncoso, Seth Blackshaw, Lindsey R. Hayes, Shuying Sun, Philip C. Wong, Jonathan P. Ling
Publikováno v:
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-17 (2024)
Abstract Background Cytoplasmic inclusions and loss of nuclear TDP-43 are key pathological features found in several neurodegenerative disorders, suggesting both gain- and loss-of-function mechanisms of disease. To study gain-of-function, TDP-43 over
Externí odkaz:
https://doaj.org/article/57aa4877bd6841eeb1d7825c31059ce8
Autor:
Xi Zhang, Tanuza Das, Tiffany F. Chao, Vickie Trinh, Rogger P. Carmen-Orozco, Jonathan P. Ling, Petr Kalab, Lindsey R. Hayes
Publikováno v:
iScience, Vol 27, Iss 6, Pp 110109- (2024)
Summary: TDP-43 nuclear clearance and cytoplasmic aggregation are hallmarks of TDP-43 proteinopathies. We recently demonstrated that binding to endogenous nuclear GU-rich RNAs sequesters TDP-43 in the nucleus by restricting its passive nuclear export
Externí odkaz:
https://doaj.org/article/4a95f8e106484c80bca2d789dc2e91c2
Autor:
Tamaralayefa Agbiki, Richard Arm, David W. Hewson, Sandor Erdody, Andrew M. Norris, Ricardo Correia, Sergiy Korposh, Barrie R. Hayes-Gill, Arash Shahidi, Stephen P. Morgan
Publikováno v:
BJA Open, Vol 10, Iss , Pp 100290- (2024)
Introduction: Leakage of orogastric secretions past the cuff of a tracheal tube is a contributory factor in ventilator-associated pneumonia. Current bench test methods specified in the International Standard for Anaesthetic and Respiratory Equipment
Externí odkaz:
https://doaj.org/article/aae6b2d2775f438ea0e9ae65bbcf7e2a
Publikováno v:
PLoS Biology, Vol 22, Iss 2, p e3002527 (2024)
TDP-43 is an essential RNA-binding protein strongly implicated in the pathogenesis of neurodegenerative disorders characterized by cytoplasmic aggregates and loss of nuclear TDP-43. The protein shuttles between nucleus and cytoplasm, yet maintaining
Externí odkaz:
https://doaj.org/article/ddfcfb1161544515a1ac63c794eb33f9