Zobrazeno 1 - 10
of 367
pro vyhledávání: '"R. Hal Scofield"'
Autor:
Stephanie Lawrence, R. Hal Scofield
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 41, Iss , Pp 100849- (2024)
Conventional human stress responses are mediated by the sympathetic adrenal medullar (SAM) axis and the hypothalamic pituitary adrenal (HPA) axis. The SAM axis mediates the immediate response to stress through norepinephrine and epinephrine while the
Externí odkaz:
https://doaj.org/article/b236206bba6948de8cab720bfea2c8e8
Autor:
Bhuwan Khatri, Kandice L. Tessneer, Astrid Rasmussen, Farhang Aghakhanian, Tove Ragna Reksten, Adam Adler, Ilias Alevizos, Juan-Manuel Anaya, Lara A. Aqrawi, Eva Baecklund, Johan G. Brun, Sara Magnusson Bucher, Maija-Leena Eloranta, Fiona Engelke, Helena Forsblad-d’Elia, Stuart B. Glenn, Daniel Hammenfors, Juliana Imgenberg-Kreuz, Janicke Liaaen Jensen, Svein Joar Auglænd Johnsen, Malin V. Jonsson, Marika Kvarnström, Jennifer A. Kelly, He Li, Thomas Mandl, Javier Martín, Gaétane Nocturne, Katrine Brække Norheim, Øyvind Palm, Kathrine Skarstein, Anna M. Stolarczyk, Kimberly E. Taylor, Maria Teruel, Elke Theander, Swamy Venuturupalli, Daniel J. Wallace, Kiely M. Grundahl, Kimberly S. Hefner, Lida Radfar, David M. Lewis, Donald U. Stone, C. Erick Kaufman, Michael T. Brennan, Joel M. Guthridge, Judith A. James, R. Hal Scofield, Patrick M. Gaffney, Lindsey A. Criswell, Roland Jonsson, Per Eriksson, Simon J. Bowman, Roald Omdal, Lars Rönnblom, Blake Warner, Maureen Rischmueller, Torsten Witte, A. Darise Farris, Xavier Mariette, Marta E. Alarcon-Riquelme, PRECISESADS Clinical Consortium, Caroline H. Shiboski, Sjögren’s International Collaborative Clinical Alliance (SICCA), Marie Wahren-Herlenius, Wan-Fai Ng, UK Primary Sjögren’s Syndrome Registry, Kathy L. Sivils, Indra Adrianto, Gunnel Nordmark, Christopher J. Lessard
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-3 (2023)
Externí odkaz:
https://doaj.org/article/38d950a26aca41828a73087f5c462f45
Autor:
Bhuwan Khatri, Kandice L. Tessneer, Astrid Rasmussen, Farhang Aghakhanian, Tove Ragna Reksten, Adam Adler, Ilias Alevizos, Juan-Manuel Anaya, Lara A. Aqrawi, Eva Baecklund, Johan G. Brun, Sara Magnusson Bucher, Maija-Leena Eloranta, Fiona Engelke, Helena Forsblad-d’Elia, Stuart B. Glenn, Daniel Hammenfors, Juliana Imgenberg-Kreuz, Janicke Liaaen Jensen, Svein Joar Auglænd Johnsen, Malin V. Jonsson, Marika Kvarnström, Jennifer A. Kelly, He Li, Thomas Mandl, Javier Martín, Gaétane Nocturne, Katrine Brække Norheim, Øyvind Palm, Kathrine Skarstein, Anna M. Stolarczyk, Kimberly E. Taylor, Maria Teruel, Elke Theander, Swamy Venuturupalli, Daniel J. Wallace, Kiely M. Grundahl, Kimberly S. Hefner, Lida Radfar, David M. Lewis, Donald U. Stone, C. Erick Kaufman, Michael T. Brennan, Joel M. Guthridge, Judith A. James, R. Hal Scofield, Patrick M. Gaffney, Lindsey A. Criswell, Roland Jonsson, Per Eriksson, Simon J. Bowman, Roald Omdal, Lars Rönnblom, Blake Warner, Maureen Rischmueller, Torsten Witte, A. Darise Farris, Xavier Mariette, Marta E. Alarcon-Riquelme, PRECISESADS Clinical Consortium, Caroline H. Shiboski, Sjögren’s International Collaborative Clinical Alliance (SICCA), Marie Wahren-Herlenius, Wan-Fai Ng, UK Primary Sjögren’s Syndrome Registry, Kathy L. Sivils, Indra Adrianto, Gunnel Nordmark, Christopher J. Lessard
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
The genetic architecture underlying Sjögren’s syndrome is not fully understood. Here, the authors perform a genome-wide association study to identify 10 new genetic risk regions, implicating genes involved in immune and salivary gland function.
Externí odkaz:
https://doaj.org/article/ee17c34d06624822ae2f0ffc7f740171
Autor:
R. Hal Scofield, Valerie M. Lewis, Joshua Cavitt, Biji T. Kurien, Shervin Assassi, Javier Martin, Olga Gorlova, Peter Gregersen, Annette Lee, Lisa G. Rider, Terrance O'Hanlon, Simon Rothwell, James Lilleker, Myositis Genetics Consortium, Xiaoxi Liu, Yuta Kochi, Chikacshi Terao, Ann Igoe, Wendy Stevens, Joanne Sahhar, Janet Roddy, Maureen Rischmueller, Sue Lester, Susanna Proudman, Sixia Chen, Matthew A. Brown, Maureen D. Mayes, Janine A. Lamb, Frederick W. Miller
Publikováno v:
ACR Open Rheumatology, Vol 4, Iss 6, Pp 528-533 (2022)
Objective We undertook this study to examine the X chromosome complement in participants with systemic sclerosis (SSc) as well as idiopathic inflammatory myopathies. Methods The participants met classification criteria for the diseases. All participa
Externí odkaz:
https://doaj.org/article/90a338f5d00f46228fb14f87661cb4a4
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Most B cells produced in the bone marrow have some level of autoreactivity. Despite efforts of central tolerance to eliminate these cells, many escape to periphery, where in healthy individuals, they are rendered functionally non-responsive to restim
Externí odkaz:
https://doaj.org/article/4370338b7f7a4396bc9acf797ffd2fae
Autor:
Jayakanthan Kabeerdoss, Debashish Danda, Ruchika Goel, Hindhumathi Mohan, Sumita Danda, R. Hal Scofield
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Background: Takayasu’s Arteritis (TA) is a chronic inflammatory disease that affects aorta and its main branches at their origin. Genetic, pathological and functional studies have shown that CD8 and Gamma delta (γ/δ) T-lymphocytes are involved in
Externí odkaz:
https://doaj.org/article/7161d2c16e494164831cfca2ed237773
Autor:
Bhuwan Khatri, Kandice L. Tessneer, Astrid Rasmussen, Farhang Aghakhanian, Tove Ragna Reksten, Adam Adler, Ilias Alevizos, Juan-Manuel Anaya, Lara A. Aqrawi, Eva Baecklund, Johan G. Brun, Sara Magnusson Bucher, Maija-Leena Eloranta, Fiona Engelke, Helena Forsblad-d’Elia, Stuart B. Glenn, Daniel Hammenfors, Juliana Imgenberg-Kreuz, Janicke Liaaen Jensen, Svein Joar Auglænd Johnsen, Malin V. Jonsson, Marika Kvarnström, Jennifer A. Kelly, He Li, Thomas Mandl, Javier Martín, Gaétane Nocturne, Katrine Brække Norheim, Øyvind Palm, Kathrine Skarstein, Anna M. Stolarczyk, Kimberly E. Taylor, Maria Teruel, Elke Theander, Swamy Venuturupalli, Daniel J. Wallace, Kiely M. Grundahl, Kimberly S. Hefner, Lida Radfar, David M. Lewis, Donald U. Stone, C. Erick Kaufman, Michael T. Brennan, Joel M. Guthridge, Judith A. James, R. Hal Scofield, Patrick M. Gaffney, Lindsey A. Criswell, Roland Jonsson, Per Eriksson, Simon J. Bowman, Roald Omdal, Lars Rönnblom, Blake Warner, Maureen Rischmueller, Torsten Witte, A. Darise Farris, Xavier Mariette, Marta E. Alarcon-Riquelme, PRECISESADS Clinical Consortium, Caroline H. Shiboski, Sjögren’s International Collaborative Clinical Alliance (SICCA), Marie Wahren-Herlenius, Wan-Fai Ng, UK Primary Sjögren’s Syndrome Registry, Kathy L. Sivils, Indra Adrianto, Gunnel Nordmark, Christopher J. Lessard
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/75a032d749534f8d9af7665484459379
Autor:
Astrid Rasmussen, Donald U. Stone, C. Erick Kaufman, Kimberly S. Hefner, Nicole R. Fram, Rhea L. Siatkowski, Andrew J. W. Huang, James Chodosh, Pablo T. Rasmussen, Dustin A. Fife, Nathan Pezant, Kiely Grundahl, Lida Radfar, David M. Lewis, Michael H. Weisman, Swamy Venuturupalli, Daniel J. Wallace, Nelson L. Rhodus, Michael T. Brennan, Courtney G. Montgomery, Christopher J. Lessard, R. Hal Scofield, Kathy L. Sivils
Publikováno v:
ACR Open Rheumatology, Vol 1, Iss 5, Pp 292-302 (2019)
Objective The objective of this study was to assess the performance and reproducibility of the two currently used ocular surface staining scores in the assessment of keratoconjunctivitis sicca in Sjögren syndrome (SS) research classification. Method
Externí odkaz:
https://doaj.org/article/552f7214c8d347e4991947424a1c3f98
Autor:
Akinsola Oyelakin, Erich Horeth, Eun-Ah Christine Song, Sangwon Min, Monika Che, Brandon Marzullo, Christopher J. Lessard, Astrid Rasmussen, Lida Radfar, R. Hal Scofield, David M. Lewis, Donald U. Stone, Kiely Grundahl, Scott S. De Rossi, Zoya Kurago, A. Darise Farris, Kathy L. Sivils, Satrajit Sinha, Jill M. Kramer, Rose-Anne Romano
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Primary Sjögren’s syndrome (pSS) is a systemic autoimmune disease characterized primarily by immune-mediated destruction of exocrine tissues, such as those of the salivary and lacrimal glands, resulting in the loss of saliva and tear production, r
Externí odkaz:
https://doaj.org/article/3fb65dfaf93a4c61bca5997a1f95724b
Autor:
Kerry M. Leehan, Nathan P. Pezant, Astrid Rasmussen, Kiely Grundahl, Jacen S. Moore, Lida Radfar, David M. Lewis, Donald U. Stone, Christopher J. Lessard, Nelson L. Rhodus, Barbara M. Segal, C. Erick Kaufman, R. Hal Scofield, Kathy L. Sivils, Courtney Montgomery, A. Darise Farris
Publikováno v:
Autoimmunity, Vol 50, Iss 8, Pp 451-457 (2017)
Objective: Determine the presence and assess the extent of fatty infiltration of the minor salivary glands (SG) of primary SS patients (pSS) as compared to those with non-SS sicca (nSS). Methods: Minor SG biopsy samples from 134 subjects with pSS (n
Externí odkaz:
https://doaj.org/article/1b592669479648e0ad849ce0e4b98570