Zobrazeno 1 - 10 of 244 pro vyhledávání: '"R. Haga"'
1
Akademický článek
The immune response to lumpy skin disease virus in cattle is influenced by inoculation route
Autor: Petra C. Fay, Najith Wijesiriwardana, Henry Munyanduki, Beatriz Sanz-Bernardo, Isabel Lewis, Ismar R. Haga, Katy Moffat, Arnoud H. M. van Vliet, Jayne Hope, Simon P. Graham, Philippa M. Beard
Publikováno v: Frontiers in Immunology, Vol 13 (2022)
Lumpy skin disease virus (LSDV) causes severe disease in cattle and water buffalo and is transmitted by hematophagous arthropod vectors. Detailed information of the adaptive and innate immune response to LSDV is limited, hampering the development of
Externí odkaz: https://doaj.org/article/53140bba0af442f2b3372877125570a0
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2
Akademický článek
IFI16 and cGAS cooperate in the activation of STING during DNA sensing in human keratinocytes
Autor: Jessica F. Almine, Craig A. J. O’Hare, Gillian Dunphy, Ismar R. Haga, Rangeetha J. Naik, Abdelmadjid Atrih, Dympna J. Connolly, Jordan Taylor, Ian R. Kelsall, Andrew G. Bowie, Philippa M. Beard, Leonie Unterholzner
Publikováno v: Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
The role of IFI16 as a DNA sensor is highly controversial. With support from aNature Communications back-to-back publication from Jønsson et al., the authors here provide functional evidence that IFI16 is involved in DNA sensing via the cGAS-STING p
Externí odkaz: https://doaj.org/article/eb5ed45912da4959a911474e177edfb0
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4
Lumpy Skin Disease Is Characterized by Severe Multifocal Dermatitis With Necrotizing Fibrinoid Vasculitis Following Experimental Infection
Autor: Neil Macintyre, Kris De Clercq, Philippa C. Hawes, Linda R. Morrison, Beatriz Sanz-Bernardo, Ismar R. Haga, John Atkinson, Karin E. Darpel, Jennifer Simpson, Emiliana Brocchi, Philippa M. Beard, Andy Haegeman, Najith Wijesiriwardana
Publikováno v: sanz-bernardo, B, Haga, I, wijesiriwardana, N, hawes, P, simpson, J, Morrison, L, Macintyre, N, brocchi, E, atkinson, J, Haegeman, A, DeClercq, K, darpel, K & Beard, P 2020, ' Lumpy skin disease is characterised by severe multifocal dermatitis with necrotising fibrinoid vasculitis following experimental infection ', Veterinary Pathology . https://doi.org/10.1177/0300985820913268
Veterinary Pathology
Lumpy skin disease is a high-consequence disease in cattle caused by infection with the poxvirus lumpy skin disease virus (LSDV). The virus is endemic in most countries in Africa and an emerging threat to cattle populations in Europe and Asia. As LSD
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbef58184e0b364db6b175b665ffff28
https://doi.org/10.1177/0300985820913268
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5
Akademický článek
Pearls for Starting a Headache Surgery Practice in Academic and Private Practice
Autor: M. Saad, L. Connor, M.H.J. Hazewinkel, Z.M. Peled, R. Hagan, L. Gfrerer, S.A. Kassis
Publikováno v: JPRAS Open, Vol 39, Iss , Pp 127-131 (2024)
Summary: There has been a growing body of evidence indicative of the effectiveness of headache surgery in treating patients with refractory headache disorders. The American Society of Plastic Surgeons issued a Policy Statement in 2018 stating that pe
Externí odkaz: https://doaj.org/article/ff97fc2229b643d6940a46a9f9321d81
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6
Akademický článek
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7
A novel strain of lumpy skin disease virus causes clinical disease in cattle in Hong Kong
Autor: Simon King, Noemi Polo, Martin Ashby, Patrick Pun, Ismar R. Haga, John Flannery, Carrie Batten, Andy Law, Andrew D. Ferguson, Amanda Corla, Barbara Shih, Anne Ching-Nga Tse, Samantha Lycett, Jason Chan, Christopher J. Brackman, Philippa M. Beard, Graham L Freimanis
Publikováno v: Flannery, J, Shih, B, Haga, I R, Ashby, M, Corla, A, King, S, Freimanis, G, Polo, N, Tse, A C-N, Brackman, C J, Chan, J, Pun, P, Ferguson, A D, Law, A, Lycett, S, Batten, C & Beard, P M 2021, ' A novel strain of lumpy skin disease virus causes clinical disease in cattle in Hong Kong ', Transboundary and Emerging Diseases . https://doi.org/10.1111/tbed.14304
Lumpy skin disease virus (LSDV) is an emerging poxviral pathogen of cattle that is currently spreading throughout Asia. The disease situation is of high importance for farmers and policy makers in Asia. In October 2020, feral cattle in Hong Kong deve
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19c1346f0fedf4489ed29e96448f515f
https://hdl.handle.net/20.500.11820/6d314274-372d-447d-890c-b5222054a3ad
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8
Akademický článek
A loss of function analysis of host factors influencing Vaccinia virus replication by RNA interference.
Autor: Philippa M Beard, Samantha J Griffiths, Orland Gonzalez, Ismar R Haga, Tali Pechenick Jowers, Danielle K Reynolds, Jan Wildenhain, Hille Tekotte, Manfred Auer, Mike Tyers, Peter Ghazal, Ralf Zimmer, Jürgen Haas
Publikováno v: PLoS ONE, Vol 9, Iss 6, p e98431 (2014)
Vaccinia virus (VACV) is a large, cytoplasmic, double-stranded DNA virus that requires complex interactions with host proteins in order to replicate. To explore these interactions a functional high throughput small interfering RNA (siRNA) screen targ
Externí odkaz: https://doaj.org/article/54e0675f17ff4ff48133bcd1756b2464
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9
Quantifying and Modeling the Acquisition and Retention of Lumpy Skin Disease Virus by Hematophagus Insects Reveals Clinically but Not Subclinically Affected Cattle Are Promoters of Viral Transmission and Key Targets for Control of Disease Outbreaks
Autor: Najith Wijesiriwardana, Mia White, Will Larner, Philippa C. Hawes, Karin E. Darpel, Joanne Stoner, Philippa M. Beard, Luke Alphey, Zoë Langlands, Simon Gubbins, Anthony J. Wilson, John P. Atkinson, Christopher Sanders, Carrie Batten, Ismar R. Haga, Beatriz Sanz-Bernardo, Sanjay Basu, Adriana V. Diaz, Eric Denison
Publikováno v: Journal of Virology
Sanz-Bernardo, B, Haga, I R, Wijesiriwardana, N, Basu, S, Larner, W, Diaz, A V, Langlands, Z, Denison, E, Stoner, J, White, M, Sanders, C, Hawes, P C, Wilson, A J, Atkinson, J, Batten, C, Alphey, L, Darpel, K E, Gubbins, S & Beard, P M 2021, ' Quantifying and modelling the acquisition and retention of lumpy skin disease virus by haematophagus insects reveals clinically but not subclinically-affected cattle are promoters of viral transmission and key targets for control of disease outbreaks ', Journal of Virology . https://doi.org/10.1128/JVI.02239-20
Lumpy skin disease virus (LSDV) causes a severe systemic disease characterized by cutaneous nodules in cattle. LSDV is a rapidly emerging pathogen, having spread since 2012 into Europe and Russia and across Asia.
Lumpy skin disease virus (LSDV)
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7a767e5e768621eb197f9b7c3280543
https://doi.org/10.1128/jvi.02239-20
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10
Madin-Darby bovine kidney (MDBK) cells are a suitable cell line for the propagation and study of the bovine poxvirus lumpy skin disease virus
Autor: Gessica Tore, Najith Wijesiriwardana, Ismar R. Haga, Barbara Shih, Petra C. Fay, Alix Carpentier, Charlotte G. Cook, Graham L Freimanis, Loic Comtet, Philippa M. Beard
Publikováno v: Fay, P, Cook, C, Wijesiriwardana, N, Tore, G, Comtet, L, Carpentier, A, Shih, B, Freimanis, G, Haga, I R & Beard, P M 2020, ' Madin-Darby bovine kidney (MDBK) cells are a suitable cell line for the propagation and study of the bovine poxvirus lumpy skin disease virus ', Journal of Virological Methods, pp. 113943 . https://doi.org/10.1016/j.jviromet.2020.113943
Journal of Virological Methods
Highlights • LSDV replicates to high titers (approximately 1 × 107 PFU/mL) in MDBK cells. • LSDV forms foci-like poxviral plaques in MDBK cells. • A plaque-reduction neutralisation test was developed for LSDV antibody quantitation. • A metho
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::906d40fee38153446b2e6ca766a573e6
https://www.pure.ed.ac.uk/ws/files/159608677/1_s2.0_S0166093420301956_main.pdf
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