Zobrazeno 1 - 10
of 83
pro vyhledávání: '"R. H. Wiltrout"'
Publikováno v:
Gene Therapy. 7:2113-2121
Dendritic cells (DC) that have been genetically modified to express cytokine genes may be novel tools for inducing antitumor immune responses. In the present study, the pMX retroviral vector was modified to express the mouse IL-2 (mIL-2pMX) and mouse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::539d9544255360d5c2650a4b3b378519
https://doi.org/10.1038/sj.gt.3301353
https://doi.org/10.1038/sj.gt.3301353
Publikováno v:
Blood. 88:4139-4148
Administration of recombinant human interleukin-7 (rhIL-7) to mice increases the exportation of myeloid progenitors (colony-forming unit [CFU]-c and CFU-granulocyte erythroid megakaryocyte macrophage [CFU-GEMM]) from the bone marrow (BM) to periphera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19ae238aff3fd361a4f9e25e3eee4ae3
https://doi.org/10.1182/blood.v88.11.4139.bloodjournal88114139
https://doi.org/10.1182/blood.v88.11.4139.bloodjournal88114139
Publikováno v:
The Journal of Immunology. 156:4707-4714
The mechanisms that regulate the adhesion and migration of NK cells to and across endothelium have been studied under nonflow conditions; however, the involvement of these processes in vivo is poorly understood. The present studies investigated the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df22a6a1c61a759d7e6645299d79eb1d
https://doi.org/10.4049/jimmunol.156.12.4707
https://doi.org/10.4049/jimmunol.156.12.4707
Publikováno v:
The Journal of Immunology. 153:333-342
Isolated murine splenic NK cells and the cultured murine endothelioma cell line, eEND2, were used to study the effects of cytokines on NK cell/endothelial cell adhesion. Treatment of eEND2 cells with TNF-alpha induced a marked increase (four- to seve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16cd2527b462deee548a5bb9320f1b1f
https://doi.org/10.4049/jimmunol.153.1.333
https://doi.org/10.4049/jimmunol.153.1.333
Publikováno v:
The Journal of Immunology. 152:5776-5784
These studies investigate the effects of exogenously administered recombinant human IL-7 (rhIL-7) on mouse leukocyte subsets in vivo in normal and tumor-bearing mice. The administration of rhIL-7 to normal mice caused a pronounced leukocytosis (three
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec20d21e0d713f799a4f7bf22cfc3bfd
https://doi.org/10.4049/jimmunol.152.12.5776
https://doi.org/10.4049/jimmunol.152.12.5776
Publikováno v:
The Journal of Immunology. 150:3634-3642
Human PBL (huPBL) were activated with anti-CD3 mAb in vitro and then were transferred into mice with severe combined immune deficiency (SCID) to determine the effect of activation on engraftment and to determine if the engrafted human cells could pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d088ac09c504db44e7a598decd624f8
https://doi.org/10.4049/jimmunol.150.8.3634
https://doi.org/10.4049/jimmunol.150.8.3634
Autor:
R. Forough, Z Xi, K A Engleka, T Sayers, Martin Macphee, Thomas Maciag, Stanley Friedman, R H Wiltrout
Publikováno v:
Journal of Biological Chemistry. 268:2960-2968
Fibroblast growth factor (FGF)-1(1-154), the precursor for acidic FGF-1(21-154), is a potent angiogenic polypeptide, the structure of which lacks a signal peptide sequence for secretion. To investigate the biological significance of this structural f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97758e07e38e45d379a6b88a1f5aa587
https://doi.org/10.1016/s0021-9258(18)53867-9
https://doi.org/10.1016/s0021-9258(18)53867-9
Autor:
R Jansen, G Damia, N Usui, J Keller, H Futami, H Goey, T T Back, D L Longo, F W Ruscetti, R H Wiltrout
Publikováno v:
The Journal of Immunology. 147:3342-3347
Transforming growth factor beta 1 (TGF-beta 1) has been shown to inhibit bone marrow colony formation after in vitro treatment as well as after in vivo administration to normal mice. These data suggest that TGF-beta might either protect, or further d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::046f229d7da3e4f5a708fd578992815a
https://doi.org/10.4049/jimmunol.147.10.3342
https://doi.org/10.4049/jimmunol.147.10.3342
Autor:
H Futami, R Jansen, M J MacPhee, J Keller, K McCormick, D L Longo, J J Oppenheim, F W Ruscetti, R H Wiltrout
Publikováno v:
The Journal of Immunology. 145:4121-4130
In this study, recombinant human IL-1 alpha (rhIL-1 alpha) was used to protect normal and tumor-bearing BALB/c mice from the acute toxicity caused by lethal doses of cyclophosphamide (Cy) and 5-fluorouracil. Pretreatment of mice for 7 days with 10,00
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::193a7a048f446617a740aba72bab6485
https://doi.org/10.4049/jimmunol.145.12.4121
https://doi.org/10.4049/jimmunol.145.12.4121
Publikováno v:
Apoptosis : an international journal on programmed cell death. 8(2)
Lewis lung carcinoma (3LL) cells were constitutively resistant to Fas-mediated apoptosis, but overexpression of Fas on 3LL cells allowed Fas-mediated apoptosis after crosslinking with agonist anti-Fas antibody (Jo2) in vitro. Surprisingly, Fas-overex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bd84601ce62cc5da0bcf05f8cf24cf60
https://pubmed.ncbi.nlm.nih.gov/12766475
https://pubmed.ncbi.nlm.nih.gov/12766475