Volume history effects and airway responsiveness in middle-aged and older men. The Normative Aging Study

Autor: George T. O'Connor, David Sparrow, Scott T. Weiss, Deborah Demolles, R H Ingram

Publikováno v: Scopus-Elsevier

In persons with asthma, a deep inhalation (DI) to total lung capacity may lead to bronchoconstriction. The intensity of this effect has been shown to correlate positively with the severity of inflammatory airflow obstruction and the level of methacho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5accdc3bc1c09af86c627014b9ce4e7
https://doi.org/10.1164/ajrccm.155.3.9117022

A deep breath bronchoconstricts obese asthmatics

Autor: Sushma K. Cribbs, Andrew C. Jackson, Anne M. Fitzpatrick, R. H. Ingram, Fernando Holguin

Publikováno v: The Journal of asthma : official journal of the Association for the Care of Asthma. 47(1)

Asthma is characterized by the loss of a deep breath (DB)-induced bronchodilation and bronchoprotection. Obesity causes lung restriction and increases airway resistance, which may further worsen the capacity of a DB to induce bronchodilation; however

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::336f6471e2a68feed78f77d5ebc1d1cf
https://pubmed.ncbi.nlm.nih.gov/20100022

Airway smooth muscle dynamics: A common pathway of airway obstruction in asthma

Autor: Robert H. Brown, Alan L. James, Paul G. Smith, Kenneth R. Lutchen, Reinoud Gosens, Michael J. Sanderson, Lu Wang, S. H. Gilbert, R. H. Ingram, Thai Tran, Robert S. Tepper, David H. Eidelman, Peter D. Paré, Steven S. An, Geoffrey N. Maksym, Pasquale Chitano, Peter J. Sterk, Ben Fabry, Thomas M. Murphy, Newman L. Stephens, Darryl A. Knight, Linhong Deng, Thais Mauad, Richard W. Mitchell, William T. Gerthoffer, Paulo Sérgio Panse Silveira, Howard W. Mitchell, Alastair G. Stewart, O. J. Lakser, S. J. Gunst, Judith L. Black, Srboljub M. Mijailovich, Nigel J. Fairbank, James G. Martin, Dale D. Tang, Jeffrey J. Fredberg, Wayne Mitzner, Brent E. McParland, Mara S. Ludwig, Anne-Marie Lauzon, Tony R. Bai, Lincoln E. Ford, Charles G. Irvin, Vito Brusasco, R. Robert Schellenberg, Maria Dowell, Jason H. T. Bates, Luke J. Janssen, Chun Y. Seow, Riccardo Pellegrino, Gregory G. King, Julian Solway, Andrew J. Halayko

Publikováno v: European Respiratory Journal, 29(5), 834-860. EUROPEAN RESPIRATORY SOC JOURNALS LTD
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Excessive airway obstruction is the cause of symptoms and abnormal lung function in asthma. As airway smooth muscle (ASM) is the effecter controlling airway calibre, it is suspected that dysfunction of ASM contributes to the pathophysiology of asthma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b24686a9fa2268f5b2e31d26f3ab8fb
https://research.rug.nl/en/publications/95cf7433-f1f2-40a3-b46a-7c65c377eb70

Relationships among airway-parenchymal interactions, lung responsiveness, and inflammation in asthma. Giles F. Filley Lecture

Autor: R H, Ingram

Publikováno v: Chest. 107

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::15ea4f1bf7aaee348cd47d63720ab960
https://pubmed.ncbi.nlm.nih.gov/7875001

Interaction between parenchyma and airways in chronic obstructive pulmonary disease and in asthma

Autor: T. K. Lim, N. B. Pride, R. H. Ingram

Publikováno v: The American review of respiratory disease. 143(6)

The extent of air-space destruction caused by emphysema is very variable in severe chronic obstructive pulmonary disease (COPD), constituting one of the most obvious differences between COPD and asthma. Differences in the static deflation pressure-vo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d17c159bb659a1caf04412f1253bef76
https://pubmed.ncbi.nlm.nih.gov/2048835