Development and validation of a minimally invasive and image-guided tape stripping method to sample atopic skin in children

Autor: O Yélamos, D Andersen, M Pont, P Iglesias, M Potrony, M Domínguez, A Herrero, B Alejo, J Mateu, M Røpke, N B Danneskiold-Samsøe, J Malvehy, R H Guy, S Brix, S Puig

Publikováno v: Yélamos, O, Andersen, D, Pont, M, Iglesias, P, Potrony, M, Domínguez, M, Herrero, A, Alejo, B, Mateu, J, Røpke, M, Danneskiold-Samsøe, N B, Malvehy, J, Guy, R H, Brix, S & Puig, S 2023, ' Development and validation of a minimally invasive and image-guided tape stripping method to sample atopic skin in children ', Clinical and Experimental Dermatology, vol. 48, no. 2, pp. 80-88 . https://doi.org/10.1093/ced/llac040

BackgroundMolecular skin profiling techniques, typically performed on skin samples taken by punch biopsy, have enhanced the understanding of the pathophysiology of atopic dermatitis (AD), thereby enabling the development of novel targeted therapeutic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6b5f04eabdfe660e0c31cd2f16f8b95
https://doi.org/10.1093/ced/llac040

The bioavailability of dermatological and other topically administered drugs

Autor: R H, Guy, A H, Guy, H I, Maibach, V P, Shah

Publikováno v: Pharmaceutical research. 3(5)

The literature addressing determination of the bioavailability of dermatological and other topically administered drugs has been reviewed. The various methods employed, their advantages and drawbacks, have been identified and evaluated. The state of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f7e6ad479ee74e7904cf812e866448ca
https://pubmed.ncbi.nlm.nih.gov/24271707

Effect of Aqueous Cream BP on human stratum corneum in vivo

Autor: M, Tsang, R H, Guy

Publikováno v: The British journal of dermatology. 163(5)

Aqueous Cream BP is widely prescribed to patients with eczema to relieve skin dryness. The formulation contains sodium lauryl sulphate (SLS), a chemical that is a known skin irritant and a commonly used excipient in personal care and household produc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::66bb2d2a17f1d77703ee0da8f52c2334
https://pubmed.ncbi.nlm.nih.gov/20649794

Does epidermal turnover reduce percutaneous penetration?

Autor: M B, Reddy, R H, Guy, A L, Bunge

Publikováno v: Pharmaceutical research. 17(11)

After its removal from the skin surface, chemical remaining within the skin can become systemically available. The fraction of chemical in the skin that eventually enters the body depends on the relative rates of percutaneous transport and epidermal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::340cdabc886170beb55fe31c5476945a
https://pubmed.ncbi.nlm.nih.gov/11205736

Iontophoretic permselectivity of mammalian skin: characterization of hairless mouse and porcine membrane models

Autor: A, Luzardo-Alvarez, M, Rodríguez-Fernández, J, Blanco-Méndez, R H, Guy, M B, Delgado-Charro

Publikováno v: Pharmaceutical research. 15(7)

To evaluate the transport number of Na+, and the isoelectric point, of two skin membranes frequently used for iontophoretic in vitro research.Na+ transport numbers were determined by the Hittorf method or by the measurement of membrane potential. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9d397ba0c2f2f6bcb100a3aba73921a2
https://pubmed.ncbi.nlm.nih.gov/9688048