Zobrazeno 1 - 10
of 22
pro vyhledávání: '"R. H. Baltz"'
Autor:
Patti Matsushima, Mary C. Broughton, R H Baltz, Krishna M. Madduri, Donald J. Merlo, Clive Waldron, Kathryn P. Crawford
Publikováno v:
Journal of Industrial Microbiology and Biotechnology. 27:399-402
Spinosyns A and D are the active ingredients in an insect control agent produced by fermentation of Saccharopolyspora spinosa. Spinosyns are macrolides with a 21-carbon, tetracyclic lactone backbone to which the deoxysugars forosamine and tri-O-methy
Autor:
R H Baltz
Publikováno v:
Journal of Industrial Microbiology and Biotechnology. 24:79-88
For the past 25 years, I have devoted most of my research efforts to the application of molecular genetics to yield improvement and production of novel secondary metabolites in actinomycetes. My group at Lilly Research Laboratories worked with a vari
Autor:
R H, Baltz
Publikováno v:
Antonie van Leeuwenhoek. 79(3-4)
The foundation for any strain improvement program is efficient random chemically-induced mutagenesis coupled with highly reproducible fermentation and product assays. The broad spectrum of spontaneous mutations can be leveraged in some cases by direc
Publikováno v:
Antonie van Leeuwenhoek. 78(3-4)
Spinosyns A and D are the active ingredients in a family of insect control agents produced by fermentation of Saccharopolyspora spinosa. Spinosyns are 21-carbon tetracyclic lactones to which are attached two deoxysugars. Most of the genes involved in
Autor:
C, Waldron, P, Matsushima, P R, Rosteck, M C, Broughton, J, Turner, K, Madduri, K P, Crawford, D J, Merlo, R H, Baltz
Publikováno v:
Chemistrybiology. 8(5)
Spinosad is a mixture of novel macrolide secondary metabolites produced by Saccharopolyspora spinosa. It is used in agriculture as a potent insect control agent with exceptional safety to non-target organisms. The cloning of the spinosyn biosynthetic
Autor:
R H, Baltz
Publikováno v:
Trends in microbiology. 6(2)
The genetic manipulation of Streptomyces species has been facilitated by the development of versatile cloning vectors, robust gene transfer systems and transposable elements. These molecular genetic tools have been used to construct antibiotic-produc
Publikováno v:
Antonie van Leeuwenhoek. 71(1-2)
Several transposons have been developed from the streptomycete insertion sequence IS493. They have broad host specificity in Streptomyces species and insert relatively randomly into a consensus target sequence of gNCaNTgNNy. Collectively, they have s
Autor:
R H, Baltz
Publikováno v:
Bioprocess technology. 22
Publikováno v:
Antimicrobial Agents and Chemotherapy. 21:758-763
A series of mutants of Streptomyces fradiae selected for increased production of the macrolide antibiotic tylosin was analyzed for levels of expression of macrocin O-methyltransferase, the enzyme which catalyzes the final step in the biosynthesis of
Autor:
Robert J. Linhardt, C. Cavazza, I. Chibata, T. Tosa, T. Mori, M. Fujimura, B. D. Ensley, M. Fujiwara, A. Fujiwara, C. Miyamoto, I. Goldberg, B. Stieglitz, T. Goodhue, G. C. Kydd, H. Foster, C. A. McCombs, I. J. Higgins, F. F. Hill, J. Schindler, R. Schmid, W. Preuss, A. Struve, J. H. Hsieh, S. J. Barer, P. C. Maxwell, Y. Imada, T. Osozawa, Y. Morimoto, M. Kinoshita, J. C. Knight, M. G. Wovcha, L. A. Kominek, H. J. Wolf, V. Krasnobajew, M. R. Kula, W. Hummel, H. Schutte, W. Leuchtenberger, P. Kurtzman, R. J. Bothast, J. E. VanCauwenberge, G. Manecke, U. Klussman, W. J. Marsheck, J. Jiu, P. T. Wang, J. E. McCullough, T. G. Mitchell, A. G. Barnes, J. S. Jackson, P. C. Bevan, T. Oki, A. Yoshimoto, Y. Matsuzawa, T. Inui, T. Takeuchi, H. Umezawa, K. Kouno, null Sawada, null Haruji, H. Taguchi, R. J. Seely, C. J. Sih, T. Sonoyama, B. Kageyama, T. Honjo, G. Teichmuller, J. Rabe, H. Henkel, A. Terahara, M. Tanaka, A. Teraham, J. R. Turner, V. M. Krupinski, D. S. Fukuda, R. H. Baltz, N. Udvardy, P. Cserey, I. Bartho, G. Hantos, M. Trinn, Z. Vida, J. Szejtli, E. Stadler, A. Szoke, I. Habon, E. Bal, M. E. Czurda, A. Weber, M. Kennecke, R. Müller, C. B. Biggs, J. G. Zeikus, R. J. Lamed
Publikováno v:
Applied Biochemistry and Biotechnology. 13:249-262