Zobrazeno 1 - 10
of 48
pro vyhledávání: '"R. Groleau"'
Autor:
Luling Wu, Xue Tian, Hai‐Hao Han, Jie Wang, Robin R. Groleau, Paramabhorn Tosuwan, Dr. Boontana Wannalerse, Dr. Adam C. Sedgwick, Prof. Steven D. Bull, Prof. Xiao‐Peng He, Prof. Tony D. James
Publikováno v:
ChemistryOpen, Vol 8, Iss 12, Pp 1407-1409 (2019)
Abstract Herein, we report the evaluation and synthesis of a reaction based fluorescent probe DCM‐Bpin for the detection of Peroxynitrite (ONOO−). DCM‐Bpin exhibits selective fluorescence off‐on response for ONOO− over other reactive oxygen
Externí odkaz:
https://doaj.org/article/8ec7365cf8da4036b848706869480a4c
Autor:
Luling Wu, Jihong Liu, Xue Tian, Robin R. Groleau, Beidou Feng, Yonggang Yang, Adam C. Sedgwick, Hai-Hao Han, Yang Wang, Han-Min Wang, Fang Huang, Steven D. Bull, Hua Zhang, Chusen Huang, Yi Zang, Jia Li, Xiao-Peng He, Ping Li, Bo Tang, Tony D. James, Jonathan L. Sessler
Publikováno v:
Journal of the American Chemical Society
Changes in adenosine triphosphate (ATP) and peroxynitrite (ONOO–) concentrations have been correlated in a number of diseases including ischemia-reperfusion injury and drug-induced liver injury. Herein, we report the development of a fluorescent pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c58ac5990b76837a6ded0d79b1066c19
https://doi.org/10.1021/jacs.1c07954
https://doi.org/10.1021/jacs.1c07954
Autor:
Sylvain F. Royer, Xuan Gao, Robin R. Groleau, Marc W. van der Kamp, Steven D. Bull, Michael J. Danson, Susan J. Crennell
Publikováno v:
Royer, S F, Gao, X, Groleau, R R, Van der Kamp, M W, Bull, S D, Danson, M J & Crennell, S J 2022, ' Structurally Informed Mutagenesis of a Stereochemically Promiscuous Aldolase Produces Mutants That Catalyze the Diastereoselective Syntheses of All Four Stereoisomers of 3-Deoxy-hexulosonic Acid ', ACS Catalysis, vol. 12, no. 18, pp. 11444–11455 . https://doi.org/10.1021/acscatal.2c03285
A 2-keto-3-deoxygluconate aldolase from the hyperthermophile Sulfolobus solfataricus catalyzes the nonstereoselective aldol reaction of pyruvate and d-glyceraldehyde to produce 2-keto-3-deoxygluconate (d-KDGlc) and 2-keto-3-deoxy-d-galactonate (d-KDG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78b6d4c96ba3044184ff63ead2e5d7e5
https://hdl.handle.net/1983/d48d0d06-2953-4693-b20e-046ce97900d9
https://hdl.handle.net/1983/d48d0d06-2953-4693-b20e-046ce97900d9
Autor:
Steven D. Bull, Robin R. Groleau, Luling Wu, Jihong Liu, Xue Tian, Tony D. James, Bo Tang, Ping Li
Publikováno v:
Chemical Science
Drug-induced liver injury (DILI) is an important cause of potentially fatal liver disease. Herein, we report the development of a molecular probe (LW-OTf) for the detection and imaging of two biomarkers involved in DILI. Initially, primary reactive o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57a76ff251b961522d5ba9405d85b43d
http://europepmc.org/articles/PMC8179478
http://europepmc.org/articles/PMC8179478
Autor:
Steven D. Bull, Harry Ley-Smith, Tony D. James, Robin R. Groleau, Liyuan Liu, Robert S. L. Chapman
Publikováno v:
The Journal of Organic Chemistry. 85:1208-1215
A practically simple three-component chiral derivatization protocol has been developed to determine the enantiopurity of eight S-chiral sulfinamides by 1H and 19F NMR spectroscopic analysis, based on their treatment with a 2-formylphenylboronic acid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df7ddf4d498f358fe8f5c3d8e41b2b50
https://doi.org/10.1021/acs.joc.9b02473
https://doi.org/10.1021/acs.joc.9b02473
Autor:
Xiao-Peng He, Jihong Liu, Tony D. James, Yonggang Yang, Jia Li, Ping Li, Chusen Huang, Luling Wu, Bo Tang, Xue Tian, Steven D. Bull, Yi Zhang, Yang Wang, Adam C. Sedgwick, Fang Huang, Jonathan L. Sessler, Hua Zhang, Han-Min Wang, Hai-Hao Han, Robin R. Groleau
The concentrations of ATP and ONOO− have been correlated with the progression a number of diseases including ischemia-reperfusion injury and drug-induced liver injury. Here, we report the development of fluorescent probe, ATP-LW, which enables the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::055bc15b1dad02fe259d197ec27f2a52
https://doi.org/10.33774/chemrxiv-2021-wlr8s
https://doi.org/10.33774/chemrxiv-2021-wlr8s
Autor:
Tony D. James, Shaun Reeksting, Jie Wang, Xue Tian, Luling Wu, Adam C. Sedgwick, Xiao-Peng He, Steven D. Bull, Hai Hao Han, Robin R. Groleau
Publikováno v:
RSC advances. 10(23)
A coumarin-based novel ‘AND’ logic fluorescent probe ROS-AHC has been developed for the simultaneous detection of ONOO− and biological thiols. ROS-AHC was shown to exhibit only a very small fluorescence response upon addition of a single GSH or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e70fca1057d8a0fdd6224076ee8ed99
https://pubmed.ncbi.nlm.nih.gov/35493005
https://pubmed.ncbi.nlm.nih.gov/35493005
Autor:
Tony D. James, Jie Wang, Steven D. Bull, Luling Wu, Paramabhorn Tosuwan, Hai Hao Han, Xiao-Peng He, Xue Tian, Adam C. Sedgwick, Robin R. Groleau, Boontana Wannalerse
Publikováno v:
ChemistryOpen, Vol 8, Iss 12, Pp 1407-1409 (2019)
ChemistryOpen
ChemistryOpen
Herein, we report the evaluation and synthesis of a reaction based fluorescent probe DCM‐Bpin for the detection of Peroxynitrite (ONOO−). DCM‐Bpin exhibits selective fluorescence off‐on response for ONOO− over other reactive oxygen species,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fa05f5d018df92b3bb5443e5b59eefa
https://doaj.org/article/8ec7365cf8da4036b848706869480a4c
https://doaj.org/article/8ec7365cf8da4036b848706869480a4c
Autor:
Robin R, Groleau, Robert S L, Chapman, Harry, Ley-Smith, Liyuan, Liu, Tony D, James, Steven D, Bull
Publikováno v:
The Journal of organic chemistry. 85(2)
A practically simple three-component chiral derivatization protocol has been developed to determine the enantiopurity of eight
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d8d10e177b885ff9b0e681ec08acf324
https://pubmed.ncbi.nlm.nih.gov/31774680
https://pubmed.ncbi.nlm.nih.gov/31774680