Zobrazeno 1 - 10
of 33
pro vyhledávání: '"R. Gordon Gould"'
Autor:
R. Gordon Gould, E.A. Swyryd
Publikováno v:
Journal of Lipid Research, Vol 7, Iss 5, Pp 698-707 (1966)
An inhibition in the conversion of mevalonate to cholesterol has been demonstrated in liver of cholesterol-fed rats by both in vitro and in vivo methods. Synthesis decreased to 30% of the control value after 1 week and 20% after 1 month on a 1% chole
Externí odkaz:
https://doaj.org/article/080bcab544c44cdba8fc22be12297ca8
Publikováno v:
Journal of Lipid Research, Vol 6, Iss 3, Pp 369-376 (1965)
α-p-Chlorophenoxyisobutyrate (CPIB) or a mixture of CPIB with a small amount of androsterone (Atromid) fed to rats at a level of 0.3% of the diet was found to increase the liver weight by about 25%, and to decrease the cholesterol concentration in l
Externí odkaz:
https://doaj.org/article/8684dda920dd410d8460ddcf1321aba6
Publikováno v:
Journal of Lipid Research, Vol 13, Iss 3, Pp 396-401 (1972)
The existence of a circadian rhythm in the rate of hepatic cholesterol synthesis in the rat has been demonstrated in vivo by measuring the conversion of both [1-14C]acetate and 3H2O to cholesterol. By both methods there was observed a similar increas
Externí odkaz:
https://doaj.org/article/5a85f421c8324da2b35b6fbe3eda889a
Autor:
Renu A. Heller, R. Gordon Gould
Publikováno v:
Journal of Biological Chemistry. 249:5254-5260
Soluble 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMG-CoA reductase, EC 1.1.1.34) from rat liver microsomes has been shown to be inactivated reversibly by cold temperature whereas microsomal enzyme did not show any cold sensitivity. At 0° the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8341e96288b4e84fd6ad5edddeac1080
https://doi.org/10.1016/s0021-9258(19)42356-9
https://doi.org/10.1016/s0021-9258(19)42356-9
Autor:
Peter A. Edwards, R. Gordon Gould
Publikováno v:
Journal of Biological Chemistry. 249:2891-2896
The circadian rhythm in the level of activity of rat hepatic β-hydroxy-β-methylglutaryl-CoA reductase (EC 1.1.1.34) is characterized by a rapid, 5- to 8-fold increase in activity from the basal level (9 a.m. to 4 p.m.) to a peak at midnight followe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3b46397f80f20300325a92c8a5c1e97
https://doi.org/10.1016/s0021-9258(19)42714-2
https://doi.org/10.1016/s0021-9258(19)42714-2
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 409:59-67
Cholesterol has been shown to be present in rat liver chromatin isolated by methods designed to avoid contamination by membrane fragments. Evidence that the cholesterol was actually a component of chromatin includes (a) the constancy of the amount (1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25a9cd1248873d46be3567e919b235cc
https://doi.org/10.1016/0005-2760(75)90080-6
https://doi.org/10.1016/0005-2760(75)90080-6
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 620:70-79
A rapid, biphasic inhibition of rat hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase (mevalonate:NADP+ oxidoreductase (CoA-acylating), EC 1.1.1.34) was induced by intragastric administration of R,S-mevalonolactone. The initial phase had a t12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1ac6ff51d42ac5982c4f1725686d5c0
https://doi.org/10.1016/0005-2760(80)90186-1
https://doi.org/10.1016/0005-2760(80)90186-1
Autor:
R. Gordon Gould, John A. Luetscher
Publikováno v:
Journal of Chromatography A. 13:350-353
Tetrahydrocortisone, tetrahydrocortisol, and allotetrahydrocortisol can be separated by gas—liquid chromatography and quantitated with an argon ionization detector. The retention times of these cortisol metabolites are identical with those of their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e30b49ab125179d6be3167a423212f2
https://doi.org/10.1016/s0021-9673(01)95129-5
https://doi.org/10.1016/s0021-9673(01)95129-5
Publikováno v:
Journal of Biological Chemistry. 177:717-726
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e382832ef081041071f7961425374f19
https://doi.org/10.1016/s0021-9258(18)57016-2
https://doi.org/10.1016/s0021-9258(18)57016-2
Autor:
R. Gordon Gould, Walter A. Jacobs
Publikováno v:
Journal of Biological Chemistry. 126:67-76
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c5543152fc1c102a9fbe8ce945b3d31
https://doi.org/10.1016/s0021-9258(18)73895-7
https://doi.org/10.1016/s0021-9258(18)73895-7