Zobrazeno 1 - 10
of 164
pro vyhledávání: '"R. Gigg"'
Publikováno v:
European Journal of Medicinal Chemistry. 32:535-540
Summary α-Trinositol analogues, including methyl ethers, deoxy, oxa and aza derivatives were prepared. The parent compound possesses weak analgesic and anti-inflammatory properties. Removal of the non-phosphorylated hydroxyls generates a compound de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93ada35eefcba0d0123b1f2a3a27bf2e
https://doi.org/10.1016/s0223-5234(97)84017-2
https://doi.org/10.1016/s0223-5234(97)84017-2
Autor:
Peter J. Parker, Lodewijk V. Dekker, R Gigg, Ruediger Woscholski, J.A. Le Good, Ruth H. Palmer
Publikováno v:
Journal of Biological Chemistry. 270:22412-22416
As potential targets for polyphosphoinositides, activation of protein kinase C (PKC) isotypes (beta 1, epsilon, zeta, nu) and a member of the PKC-related kinase (PRK) family, PRK1, has been compared in vitro. PRK1 is shown to be activated by both pho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89916207a9c672487996e24c6ef5874f
https://doi.org/10.1074/jbc.270.38.22412
https://doi.org/10.1074/jbc.270.38.22412
Publikováno v:
Acta Crystallographica Section B Structural Science. 49:708-718
(±)-3,4-Di-O-acetyl-,2,5,6-tetra-O-benzyl-myo-inositol, C 38 H 40 O 8 , M r =624.7 («jumping crystal»). Three monoclinic crystal forms. Form I, T= 18 o C, P2 1 /n, a=28.883 (3), b=15.189 (2), c= 15.566 (2) A, β=100.37 (1) o , V=6717 (1) A 3 , Z=
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c9e07c767bb184a892e36beacb6fbbf
https://doi.org/10.1107/s0108768193000795
https://doi.org/10.1107/s0108768193000795
Publikováno v:
ChemInform. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15ca6058673e1fc84a093068934e880f
https://doi.org/10.1002/chin.199643196
https://doi.org/10.1002/chin.199643196
Publikováno v:
ChemInform. 28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f906b6645d07854cdb2181f1c9b18b58
https://doi.org/10.1002/chin.199750329
https://doi.org/10.1002/chin.199750329
Publikováno v:
The Journal of biological chemistry. 270(38)
As potential targets for polyphosphoinositides, activation of protein kinase C (PKC) isotypes (beta 1, epsilon, zeta, nu) and a member of the PKC-related kinase (PRK) family, PRK1, has been compared in vitro. PRK1 is shown to be activated by both pho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::35aa863b05dc9c963b18c91bd12be833
https://pubmed.ncbi.nlm.nih.gov/7673228
https://pubmed.ncbi.nlm.nih.gov/7673228
Publikováno v:
Molecular pharmacology. 47(6)
The novel, synthetic, adenophostin A analogue 2-hydroxyethyl-alpha-D-glucopyranoside-2,3',4'-trisphosphate [Glu(2,3',4')P3] was synthesized to probe the structure-activity relationship at the D-myo-inositol-1,4,5-trisphosphate [Ins(1,4,5)P3] receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e2f0bb69d39c4893c190044edd619e7a
https://pubmed.ncbi.nlm.nih.gov/7603461
https://pubmed.ncbi.nlm.nih.gov/7603461
Autor:
M, Abdullah, P J, Hughes, A, Craxton, R, Gigg, T, Desai, J F, Marecek, G D, Prestwich, S B, Shears
Publikováno v:
The Journal of biological chemistry. 267(31)
The metabolism of inositol 1,3,4-trisphosphate is a pivotal branch point of inositol phosphate turnover; its dephosphorylation replenishes cellular inositol pools, its phosphorylation at the 6-position supports the synthesis of inositol pentakisphosp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::782d76e77c6d3e45675255d5c3c67fdb
https://pubmed.ncbi.nlm.nih.gov/1331051
https://pubmed.ncbi.nlm.nih.gov/1331051
Publikováno v:
ChemInform. 21
The chemical syntheses of the carbohydrate portions of the naturally occurring glycolipids derived from the sphingosine bases (as well as the syntheses of the complete glycosphingolipids) and of myoinositol-containing lipids derived from esters of gl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7201b37f7a87d4751733ef19051263a5
https://doi.org/10.1002/chin.199043326
https://doi.org/10.1002/chin.199043326
Autor:
D. R. Bundle, G. Descotes, J. Gigg, R. Gigg, W. Klaffke, B. Meyer, J. Staněk, T. Suami, J. Thiem
Publikováno v:
Topics in Current Chemistry ISBN: 9783540515760
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2a893b0788b9d9c1776444a3f3cf2d9
https://doi.org/10.1007/bfb0111557
https://doi.org/10.1007/bfb0111557
