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Replacement of aprotinin by ε-aminocaproic acid in infants undergoing cardiac surgery: consequences for blood loss and outcome

Autor: M. Macguill, G. Wiesner, Jürgen Hörer, Klaus Martin, Manfred Vogt, Alexander Hapfelmeier, R. Gertler, N.P. Mayr, Peter Tassani

Publikováno v: British journal of anaesthesia. 110(4)

Background Once aprotinin was no longer available for clinical use, ɛ-aminocaproic acid (EACA) and tranexamic acid became the only two options for antifibrinolytic therapy. We compared aprotinin and EACA with respect to their blood-sparing efficacy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8c49d445d839db05d2cbe4f37574a13
https://pubmed.ncbi.nlm.nih.gov/23213034

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Switch from aprotinin to ε-aminocaproic acid: impact on blood loss, transfusion, and clinical outcome in neonates undergoing cardiac surgery

Autor: N.P. Mayr, M. Macguill, Peter Tassani, Christian Schreiber, Manfred Vogt, Klaus Martin, R. Gertler, G. Wiesner, H. Liermann

Publikováno v: British journal of anaesthesia. 107(6)

Background With the withdrawal of aprotinin from worldwide marketing in November 2007, many institutions treating patients at high risk for hyperfibrinolysis had to update their therapeutic protocols. At our institution, the standard was switched fro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82d3a1eb26c68adcfeb526aa3589f3b0
https://pubmed.ncbi.nlm.nih.gov/21857014

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Comparison of blood-sparing efficacy of ε-aminocaproic acid and tranexamic acid in newborns undergoing cardiac surgery

Autor: G Wiesner, A Sterner, Manfred Vogt, M. Macguill, K Martin, Jürgen Hörer, Christian Schreiber, Peter Tassani, R. Gertler

Publikováno v: The Thoracic and cardiovascular surgeon. 59(5)

Background e-Aminocaproic acid (EACA) and tranexamic acid (TXA) are used for antifibrinolytic therapy in neonates undergoing cardiac surgery, although data directly comparing their blood-sparing efficacy are not yet available. We compared two consecu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6080336939c681b7fc729ae09aa221b3
https://pubmed.ncbi.nlm.nih.gov/21425054

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A comparison of purging and nonpurging eating-disordered outpatients: mediating effects of weight and general psychopathology

Autor: R, O'Kearney, R, Gertler, J, Conti, M, Duff

Publikováno v: The International journal of eating disorders. 23(3)

The present study compared purging and nonpurging eating-disordered outpatients on key behavioral and psychological features of their disorder. It also investigated the possible mediating effects of current level of depression, anxiety or general psy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a62aea1cfea2b63ebb7984778914c91c
https://pubmed.ncbi.nlm.nih.gov/9547660

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