Zobrazeno 1 - 10
of 397
pro vyhledávání: '"R. Gerner"'
Autor:
Judith Behnsen, Hui Zhi, Allegra T. Aron, Vivekanandan Subramanian, William Santus, Michael H. Lee, Romana R. Gerner, Daniel Petras, Janet Z. Liu, Keith D. Green, Sarah L. Price, Jose Camacho, Hannah Hillman, Joshua Tjokrosurjo, Nicola P. Montaldo, Evelyn M. Hoover, Sean Treacy-Abarca, Benjamin A. Gilston, Eric P. Skaar, Walter J. Chazin, Sylvie Garneau-Tsodikova, Matthew B. Lawrenz, Robert D. Perry, Sean-Paul Nuccio, Pieter C. Dorrestein, Manuela Raffatellu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Zinc is an essential cofactor for bacterial metabolism. Here, the authors show that the probiotic bacterium Escherichia coli Nissle 1917 utilizes the siderophore yersiniabactin as a zincophore, allowing the microbe to grow in zinc-limited media and t
Externí odkaz:
https://doaj.org/article/19617c74d04844b3a0b478ff2c84a9cf
Autor:
Romana R. Gerner, Suzana Hossain, Artur Sargun, Kareem Siada, Grant J. Norton, Tengfei Zheng, Wilma Neumann, Sean-Paul Nuccio, Elizabeth M. Nolan, Manuela Raffatellu
Publikováno v:
mBio, Vol 13, Iss 5 (2022)
ABSTRACT Inflammatory bowel diseases (IBD) are characterized by chronic inflammation of the gastrointestinal tract and profound alterations to the gut microbiome. Adherent-invasive Escherichia coli (AIEC) is a mucosa-associated pathobiont that coloni
Externí odkaz:
https://doaj.org/article/1b65887a6d9f4da093e24d1064d852d9
Autor:
Lisa Mayr, Felix Grabherr, Julian Schwärzler, Isabelle Reitmeier, Felix Sommer, Thomas Gehmacher, Lukas Niederreiter, Gui-Wei He, Barbara Ruder, Kai T. R. Kunz, Piotr Tymoszuk, Richard Hilbe, David Haschka, Clemens Feistritzer, Romana R. Gerner, Barbara Enrich, Nicole Przysiecki, Markus Seifert, Markus A. Keller, Georg Oberhuber, Susanne Sprung, Qitao Ran, Robert Koch, Maria Effenberger, Ivan Tancevski, Heinz Zoller, Alexander R. Moschen, Günter Weiss, Christoph Becker, Philip Rosenstiel, Arthur Kaser, Herbert Tilg, Timon E. Adolph
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Dietary lipids are linked to the development of inflammatory bowel diseases through unclear mechanisms. Here, the authors report that dietary polyunsaturated fatty acids trigger intestinal inflammation resembling aspects of Crohn’s disease, which i
Externí odkaz:
https://doaj.org/article/fc87842ee61c451c8bde60fdd9105dee
Autor:
Chia-Hao Lin, Cheng-Jang Wu, Sunglim Cho, Rasika Patkar, Ling-Li Lin, Mei-Chi Chen, Elisabeth Israelsson, Joanne Betts, Magdalena Niedzielska, Shefali A. Patel, Han G. Duong, Romana R. Gerner, Chia-Yun Hsu, Matthew Catley, Rose A. Maciewicz, Hiutung Chu, Manuela Raffatellu, John T. Chang, Li-Fan Lu
Publikováno v:
bioRxiv
Regulatory T (Treg) cells are instrumental in establishing immunological tolerance. However, the precise effector mechanisms by which Treg cells control a specific type of immune response in a given tissue remains unresolved. By simultaneously studyi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::191745d22cd68b14fbab9a868827295a
https://doi.org/10.1101/2023.02.20.529261
https://doi.org/10.1101/2023.02.20.529261
Autor:
Vivekanandan Subramanian, Michael H. Lee, Daniel Petras, William Santus, Walter J. Chazin, Benjamin A. Gilston, Robert D. Perry, Sean Treacy-Abarca, Keith D. Green, Evelyn M. Hoover, Romana R. Gerner, Sarah L. Price, Pieter C. Dorrestein, Hannah Hillman, Eric P. Skaar, Sylvie Garneau-Tsodikova, Sean Paul Nuccio, Joshua Tjokrosurjo, Jose Camacho, Janet Z. Liu, Matthew B. Lawrenz, Hui Zhi, Judith Behnsen, Nicola P. Montaldo, Manuela Raffatellu, Allegra T. Aron
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications
Nature communications, vol 12, iss 1
Nature Communications
Nature communications, vol 12, iss 1
Zinc is an essential cofactor for bacterial metabolism, and many Enterobacteriaceae express the zinc transporters ZnuABC and ZupT to acquire this metal in the host. However, the probiotic bacterium Escherichia coli Nissle 1917 (or “Nissle”) exhib
Autor:
Ivan Tancevski, Manfred Nairz, Kristina Duwensee, Kristina Auer, Andrea Schroll, Christiane Heim, Clemens Feistritzer, Julia Hoefer, Romana R Gerner, Alexander R Moschen, Ingrid Heller, Petra Pallweber, Xiaorong Li, Markus Theurl, Egon Demetz, Anna M Wolf, Dominik Wolf, Philipp Eller, Andreas Ritsch, Guenter Weiss
Publikováno v:
EMBO Molecular Medicine, Vol 6, Iss 6, Pp 810-820 (2014)
Abstract Bacterial sepsis results in high mortality rates, and new therapeutics to control infection are urgently needed. Here, we investigate the therapeutic potential of fibrates in the treatment of bacterial sepsis and examine their effects on inn
Externí odkaz:
https://doaj.org/article/e61a00784a914291aca8e16820fcd83c
Autor:
Richard Hilbe, Lukas Niederreiter, Ivan Tancevski, Qitao Ran, Piotr Tymoszuk, Barbara Enrich, Maria Effenberger, Lisa Mayr, Barbara Ruder, Thomas Gehmacher, Kai T.R. Kunz, Philip Rosenstiel, Clemens Feistritzer, Christoph Becker, Alexander R. Moschen, Felix Grabherr, Susanne Sprung, David Haschka, N Przysiecki, Robert Koch, Herbert Tilg, Markus Seifert, Gui-Wei He, Julian Schwärzler, Isabelle Reitmeier, Felix Sommer, Arthur Kaser, Markus A. Keller, Romana R. Gerner, Günter Weiss, Heinz Zoller, Georg Oberhuber, Timon E. Adolph
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications
Nature Communications
The increased incidence of inflammatory bowel disease (IBD) has become a global phenomenon that could be related to adoption of a Western life-style. Westernization of dietary habits is partly characterized by enrichment with the ω-6 polyunsaturated
Autor:
Romana R. Gerner, Simon Reider, Felix Grabherr, S Macheiner, Lisa Mayr, Maria Effenberger, Alexander R. Moschen, Kerstin Siegmund, David Nachbaur, Hubert Schwaighofer, Patrizia Moser, Bernhard Texler, Robert Zeiser, Herbert Tilg, Brigitte Kircher, Herbert Oberacher
Publikováno v:
Leukemia. 34:1885-1897
Acute graft-versus-host disease (aGVHD) and tumor relapse remain major complications after allogeneic hematopoietic stem cell transplantation. Alloreactive T cells and cancer cells share a similar metabolic phenotype to meet the bioenergetic demands
Autor:
Robert H. Mills, Parambir S. Dulai, Yoshiki Vázquez-Baeza, Consuelo Sauceda, Noëmie Daniel, Romana R. Gerner, Lakshmi E. Batachari, Mario Malfavon, Qiyun Zhu, Kelly Weldon, Greg Humphrey, Marvic Carrillo-Terrazas, Lindsay DeRight Goldasich, MacKenzie Bryant, Manuela Raffatellu, Robert A. Quinn, Andrew T. Gewirtz, Benoit Chassaing, Hiutung Chu, William J. Sandborn, Pieter C. Dorrestein, Rob Knight, David J. Gonzalez
Publikováno v:
Nature microbiology, vol 7, iss 2
Ulcerative colitis (UC) is driven by disruptions in host-microbiota homoeostasis, but current treatments exclusively target host inflammatory pathways. To understand how host-microbiota interactions become disrupted in UC, we collected and analysed s
Autor:
A Kozsar, Romana R. Gerner, Christina Watschinger, N Przysiecki, Alexander R. Moschen, S Macheiner
Publikováno v:
Zeitschrift für Gastroenterologie.