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Suppression of breast cancer growth and metastasis by a serpin myoepithelium-derived serine proteinase inhibitor expressed in the mammary myoepithelial cells

Autor: Y. E. Liu, R. Gentz, Guowei Xiao, Jian Ni, Y. E. Shi, Qing-Xiang Amy Sang, I. D. Goldberg

Publikováno v: Proceedings of the National Academy of Sciences. 96:3700-3705

A serpin was identified in normal mammary gland by differential cDNA sequencing. In situ hybridization has detected this serpin exclusively in the myoepithelial cells on the normal and noninvasive mammary epithelial side of the basement membrane and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::084aca260ce57409b55e3e5bfb85c56a
https://doi.org/10.1073/pnas.96.7.3700

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Culture of human amniotic cells: A system to study interferon production

Autor: R.R. Golgher, Erna Geessien Kroon, P. C. P. Ferreira, João Rodrigues dos Santos, Alex F. Carvalho, Cláudio A. Bonjardim, R. Gentz

Publikováno v: Placenta. 19:307-314

This study investigated whether primary culture of human amniotic membrane cells (PCHAM) could be used as an in vitro model system for the study of interferon (IFN) production. PCHAM cells infected with Newcastle disease virus (NDV) produced the two

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c3833a37e634f69d67db9837b287a73
https://doi.org/10.1016/s0143-4004(98)90063-7

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A Newly Identified Member of the Tumor Necrosis Factor Receptor Superfamily with a Wide Tissue Distribution and Involvement in Lymphocyte Activation

Autor: B S, Kwon, K B, Tan, J, Ni, K O, Oh, Z H, Lee, K K, Kim, Y J, Kim, S, Wang, R, Gentz, G L, Yu, J, Harrop, S D, Lyn, C, Silverman, T G, Porter, A, Truneh, P R, Young

Publikováno v: Journal of Biological Chemistry. 272:14272-14276

The tumor necrosis factor receptor (TNFR) superfamily consists of approximately 10 characterized members of human proteins. We have identified a new member of the TNFR superfamily, TR2, from a search of an expressed sequence tag data base. cDNA cloni

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15dd934897d648a8bae5fa27f87df64b
https://doi.org/10.1074/jbc.272.22.14272

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Development of a versatile computer integrated control system for bioprocess controls

Autor: D, Kong, R, Gentz, J, Zhang

Publikováno v: Cytotechnology. 26(3)

A general approach is described for the implementation of a networked multi-unit computer integrated control system. The use of data acquisition hardware and graphical programming tools alleviates tedious programming and maintains potency and flexibi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::068b31eebd2429fddb5235a89e9a3b38
https://pubmed.ncbi.nlm.nih.gov/22358619

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Cell growth and protein formation on various microcarriers

Autor: D, Kong, M, Chen, R, Gentz, J, Zhang

Publikováno v: Cytotechnology. 29(2)

A large number of microcarriers are commercially available. The capability of cells to successfully proliferate on microcarriers varies with cell lines and media. Choosing the right microcarrier for a particular cell line is more than a choice of a m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e14352ebd55434171aa10951689e8598
https://pubmed.ncbi.nlm.nih.gov/22359063

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Proton, carbon-13, and nitrogen-15 NMR backbone assignments and secondary structure of human interferon-.gamma

Autor: R Gentz, Stephan Grzesiek, Alexander M. Labhardt, Ad Bax, Heinz Döbeli, G. Garotta

Publikováno v: Biochemistry. 31:8180-8190

1H, 13C, and 15N NMR assignments of the protein backbone of human interferon-gamma, a homodimer of 31.4 kDa, have been made using the recently introduced three-dimensional (3D) triple-resonance NMR techniques. It is shown that, despite the approximat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6c818dbd9a75faa1d412c1bee62d79a9
https://doi.org/10.1021/bi00150a009

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Both tumor necrosis factor receptor types mediate proliferative signals in human mononuclear cell activation

Autor: G Gehr, R Gentz, M Brockhaus, H Loetscher, W Lesslauer

Publikováno v: The Journal of Immunology. 149:911-917

TNF is a highly pleiotropic cytokine. The recent identification of two distinct cellular receptors for TNF may provide explanations for the many different TNF activities. We have investigated the expression of the two receptor types, TNFR alpha (75 k

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3df0ac70f84d9700fa61e9b44448ed0a
https://doi.org/10.4049/jimmunol.149.3.911

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High cell density and productivity culture of Chinese hamster ovary cells in a fluidized bed bioreactor

Autor: D, Kong, S, Cardak, M, Chen, R, Gentz, J, Zhang

Publikováno v: Cytotechnology. 29(3)

A recombinant Chinese hamster ovary clone was cultivated in a 2L Cytopilot Mini fluidized bed bioreactor using Cytoline 1 microcarriers and a 10L B. Braun stirred tank bioreactor with Cytodex 1 microcarriers. Cytoline 1 is a macroporous polyethylene

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d1f2772f62cac3af22744c553e87c469
https://pubmed.ncbi.nlm.nih.gov/19003344

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