Zobrazeno 1 - 10
of 398
pro vyhledávání: '"R. Garrod"'
Autor:
J.H. Hull, L. Ansley, C.E. Bolton, J.E. Sharman, R.K. Knight, D.J. Shale, J.R. Cockcroft, R. Garrod
Publikováno v:
Artery Research, Vol 3, Iss 4 (2009)
Background: As survival in the common autosomal recessive condition Cystic Fibrosis (CF) improves, there is focus on extra-pulmonary complications. Patients with CF have increased augmentation index (AIx) at rest which is greatest in those with diabe
Externí odkaz:
https://doaj.org/article/12c85c0260e84c83aa44c38861fd7112
Publikováno v:
Artery Research, Vol 2, Iss 3 (2008)
Externí odkaz:
https://doaj.org/article/e1f0a0e3e97345b5bc4d7e7989404af1
Autor:
Jonathan D. Humphries, Junzhe Zha, Jessica Burns, Janet A. Askari, Christopher R. Below, Megan R. Chastney, Matthew C. Jones, Aleksandr Mironov, David Knight, Derek A. O'Reilly, Mark J. Dunne, David R. Garrod, Claus Jorgensen, Martin J. Humphries
Publikováno v:
Matrix Biology. 110:16-39
Pancreatic ductal adenocarcinoma (PDAC) has a dismal prognosis due to its aggressive progression, late detection and lack of druggable driver mutations, which often combine to result in unsuitability for surgical intervention. Together with activatin
Autor:
Judith B. Fülle, Rogerio Alves de Almeida, Craig Lawless, Bian Yanes, E. Birgitte Lane, David R. Garrod, Christoph Ballestrem
Desmosomes are multiprotein adhesion complexes that link intermediate filaments to the plasma membrane, ensuring the mechanical integrity of cells across tissues, but how they participate in the wider signalling network to exert their full function i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12b6df79d02ba01b6e4b79c3026310b8
https://doi.org/10.1101/2023.03.24.534085
https://doi.org/10.1101/2023.03.24.534085
Autor:
Jihui Zhang, Jie Chen, Jonathan P. Richardson, Nicola-Jane Francis-Newton, Pei F. Lai, Kerry Jenkins, Meriel R. Major, Rebekah E. Key, Mark E. Stewart, Stuart Firth-Clark, Steven M. Lloyd, Gary K. Newton, Trevor R. Perrior, David R. Garrod, Clive Robinson
Whereas treatment of allergic diseases such as asthma relies largely on the targeting of dysregulated effector pathways, the conceptually attractive alternative of preventing them by a pharmaceutical, at-source intervention has been stymied until now
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dca52139440d614d7114940226272bd8
https://openaccess.sgul.ac.uk/id/eprint/114661/5/acsptsci.2c00022.pdf
https://openaccess.sgul.ac.uk/id/eprint/114661/5/acsptsci.2c00022.pdf
Desmosome dualism – most of the junction is stable, but a plakophilin moiety is persistently dynamic
Autor:
David Liebl, Graham D. Wright, Christoph Ballestrem, David R Garrod, Jaron Liu, Rogerio Alves de Almeida, Henri Huppert, Bian Yanes, E. Birgitte Lane, Judith B Fülle
Publikováno v:
J Cell Sci
Desmosomes, strong cell–cell junctions of epithelia and cardiac muscle, link intermediate filaments to cell membranes and mechanically integrate cells across tissues, dissipating mechanical stress. They comprise five major protein classes – desmo
Akademický článek
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Autor:
Jonathan D. Humphries, Martin J. Humphries, Matthew Jones, Junzhe Zha, Christopher R. Below, Alexander A. Mironov, David R. Garrod, David Knight, Derek A. O'Reilly, Claus Jørgensen, Megan R. Chastney, Janet A. Askari, Mark Dunne, Jessica Burns
Pancreatic ductal adenocarcinoma (PDAC) has a dismal prognosis due to its aggressive progression, late detection and lack of druggable driver mutations, which often combine to result in unsuitability for surgical intervention. Together with activatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f1158a21445e7b82aebc4d121a8cd53
https://doi.org/10.1101/2021.08.19.456969
https://doi.org/10.1101/2021.08.19.456969
Akademický článek
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Autor:
Jerry Pelletier, David R. Garrod, Jacques Genest, Michael N. Oda, Adel Schwertani, Isabelle Ruel, Hong Y. Choi, Abba Malina
Publikováno v:
European Heart Journal. 39:1194-1202
Aims The biogenesis of high-density lipoprotein (HDL) particles by cholesterol-laden foam cells in atherosclerotic lesions is crucial for the removal of excess cholesterol from the lesions. Impairment in the HDL biogenic process contributes to the pr