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Platform for the growth and propogation of HEK293 cells and adenovirus viral vector amplification

Autor: P. Lefebvre, R. Gantier, T. Haq, T. Sanderson, T. Joseph

Publikováno v: Cytotherapy. 21:S24-S25

Background & Aim Industrialization of viral vector production for gene therapy applications demands consistent processes utilizing robust production platforms and raw materials that can meet quality standards and regulatory compliance. Typical vector

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2799aad7e9605033fc55fee769da99ab
https://doi.org/10.1016/j.jcyt.2019.03.332

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A comprehensive evaluation of mixed mode interactions of HEA and PPA HyperCel™ chromatographic media

Autor: Charlotte Cabanne, Xavier Santarelli, Vignesh Narasimhan Janakiraman, R. Gantier, J. Pezzini

Publikováno v: Journal of Chromatography B. :68-77

Mixed mode or multimodal chromatography has been developed for rational use of multiple interactions in a controlled manner, in contrast to non-specific interactions. Indeed, as the term "mixed mode" suggests, these resins allow different types of in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a4642c02e7dc99a71fd43102865dcf1
https://doi.org/10.1016/j.jchromb.2014.11.020

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A study on the nature of interactions of mixed-mode ligands HEA and PPA HyperCel using phenylglyoxal modified lysozyme

Autor: R. Gantier, Charlotte Cabanne, J. Pezzini, Jean-William Dupuy, Xavier Santarelli

Publikováno v: Journal of Chromatography B. 960:209-213

Mixed mode chromatography, or multimodal chromatography, involves the exploitation of combinations of several interactions in a controlled manner, to facilitate the rapid capture of proteins. Mixed-mode ligands like HEA and PPA HyperCel™ facilitate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c0a1d85b6105d36c632648d2dbb1ba1
https://doi.org/10.1016/j.jchromb.2014.04.046

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Dedicated removal of immunoglobulin (Ig)A, IgM, and Factor (F)XI/activated FXI from human plasma IgG

Autor: R. Gantier, Thierry Burnouf, Jérôme Champagne, Yu Wen Wu, Magali Toueille

Publikováno v: Transfusion. 54:169-178

BACKGROUND: Adverse events can be associated with treating critically ill patients with immunoglobulin (Ig)G. Some adverse events are due to contaminants like IgA and activated Factor (F)XI. Therefore, new purification strategies are needed for dedic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::27dfa287310eebf90520876a8234a8cd
https://doi.org/10.1111/trf.12243

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The −2 bp deletion in exon 6 of the ‘alpha 7-like’ nicotinic receptor subunit gene is a risk factor for the P50 sensory gating deficit

Autor: Dominique Campion, Florence Thibaut, Michel Petit, Frédérique Bonnet-Brilhault, Emmanuelle Houy, G Raux, Gabrielle Allio, Maria Martinez, Thierry Frebourg, Sadeq Haouzir, S. Louchart, D. Levillain, R. Gantier

Publikováno v: Molecular Psychiatry. 7:1006-1011

Abnormality in the P50 auditory-evoked potential gating is an endophenotype associated with schizophrenia. Biochemical and genetic studies have suggested that the alpha 7 nicotinic acetylcholine receptor (nAChR) is involved in this sensory gating def

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c255e89d5feae12e0bd7b4e5eea255cb
https://doi.org/10.1038/sj.mp.4001140

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Antibody capture by mixed-mode chromatography: a comprehensive study from determination of optimal purification conditions to identification of contaminating host cell proteins

Autor: Bertrand Garbay, R. Gantier, Gilles Joucla, Anne-Marie Lomenech, J. Pezzini, Magali Toueille, Charlotte Cabanne, Xavier Santarelli, Caroline Le Sénéchal

Publikováno v: Journal of chromatography. A. 1218(45)

We evaluated mixed mode chromatography for the capture of recombinant antibodies from CHO cell culture supernatants. We studied PPA HyperCel, HEA HyperCel, MEP HyperCel and Capto adhere resins, which all contain hydrophobic and cationic groups. A mic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddefd91991a274064c14231a8fa5d410
https://pubmed.ncbi.nlm.nih.gov/21982448

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Dementia with prominent frontotemporal features associated with L113P presenilin 1 mutation

Autor: Thierry Frebourg, Patrice Verpillat, Didier Hannequin, Alexis Brice, J. Boulliat, Catherine Thomas-Antérion, Dominique Campion, R. Gantier, G Raux

Publikováno v: Neurology. 55:1577-1579

Article abstract The authors report a presenilin 1 ( PSEN1 ) mutation (L113P) in a family with six cases of dementia. The patients had personality changes and behavioral disorders, whereas spatial orientation and praxis were preserved late in the cou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a6b527dc537952ff027a847042fc44a
https://doi.org/10.1212/wnl.55.10.1577

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