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Akademický článek

Post-oral sensing of fat increases food intake and attenuates body weight defense

Autor: Molly R. Gallop, Victoria C. Wilson, Anthony W. Ferrante, Jr.

Publikováno v: Cell Reports, Vol 37, Iss 3, Pp 109845- (2021)

Summary: In mammals, changes in weight elicit responses that favor a return to one’s previous weight and promote weight stability. It has been hypothesized that palatable sweet and high-fat foods disturb the defense of body weight, leading to weigh

Externí odkaz: https://doaj.org/article/9974ba90a8bb4bdc9b8710f016b5ca1d

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Finding balance: understanding the energetics of time‐restricted feeding in mice

Autor: Molly R. Gallop, Selene Y. Tobin, Amandine Chaix

Publikováno v: Obesity. 31:22-39

Over the course of mammalian evolution, the ability to store energy likely conferred a survival advantage when food became scarce. A long-term increase in energy storage results from an imbalance between energy intake and energy expenditure, two tigh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feacbb86b7e7bd99eed9aaff62ff90d4
https://doi.org/10.1002/oby.23607

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Complex physiology and clinical implications of time-restricted eating

Autor: Max C. Petersen, Molly R. Gallop, Stephany Flores Ramos, Amir Zarrinpar, Josiane L. Broussard, Maria Chondronikola, Amandine Chaix, Samuel Klein

Publikováno v: Physiological Reviews. 102:1991-2034

Time-restricted eating (TRE) is a dietary intervention that limits food consumption to a specific time window each day. The effect of TRE on body weight and physiological functions has been extensively studied in rodent models, which have shown consi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d9b9198616f600397baf0f0fdca1151
https://doi.org/10.1152/physrev.00006.2022

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Akademický článek

Absence of Carbohydrate Response Element Binding Protein in Adipocytes Causes Systemic Insulin Resistance and Impairs Glucose Transport

Autor: Archana Vijayakumar, Pratik Aryal, Jennifer Wen, Ismail Syed, Reema P. Vazirani, Pedro M. Moraes-Vieira, Joao Paulo Camporez, Molly R. Gallop, Rachel J. Perry, Odile D. Peroni, Gerald I. Shulman, Alan Saghatelian, Timothy E. McGraw, Barbara B. Kahn

Publikováno v: Cell Reports, Vol 21, Iss 4, Pp 1021-1035 (2017)

Summary: Lower adipose-ChREBP and de novo lipogenesis (DNL) are associated with insulin resistance in humans. Here, we generated adipose-specific ChREBP knockout (AdChREBP KO) mice with negligible sucrose-induced DNL in adipose tissue (AT). Chow-fed

Externí odkaz: https://doaj.org/article/01014948a8b042bc958c1e6672bd5820

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Akademický článek

Nuclear corepressor SMRT is a strong regulator of body weight independently of its ability to regulate thyroid hormone action.

Autor: Hiroaki Shimizu, Yu Lu, Kristen R Vella, Federico Damilano, Inna Astapova, Izuki Amano, Megan Ritter, Molly R Gallop, Anthony N Rosenzweig, Ronald N Cohen, Anthony N Hollenberg

Publikováno v: PLoS ONE, Vol 14, Iss 8, p e0220717 (2019)

Silencing Mediator of Retinoid and Thyroid Hormone Receptors (SMRT) and the nuclear receptor co-repressor1 (NCoR1) are paralogs and regulate nuclear receptor (NR) function through the recruitment of a multiprotein complex that includes histone deacet

Externí odkaz: https://doaj.org/article/cd1ab538c8344a8297bad9a389a8ded8

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