Zobrazeno 1 - 10
of 500
pro vyhledávání: '"R. Gainetdinov"'
Autor:
Ilya S. Zhukov, Yazen Alnefeesi, Natalya A. Krotova, Vsevolod V. Nemets, Konstantin A. Demin, Marina N. Karpenko, Evgeny A. Budygin, Evgeny V. Kanov, Allan V. Kalueff, Petr D. Shabanov, Michael Bader, Natalia Alenina, Raul R. Gainetdinov
Publikováno v:
Frontiers in Psychiatry, Vol 15 (2024)
IntroductionAggression and self-harm disproportionately occur in youths preoccupied with social status tracking. These pathological conditions are linked to a serotonin (5-HT) deficit in the brain. Ablation of 5-HT biosynthesis by tryptophan hydroxyl
Externí odkaz:
https://doaj.org/article/bc214ef21373437cb8cf4b806ee7a45a
Autor:
Anastasia N. Vaganova, Zoia S. Fesenko, Evgeniya V. Efimova, Sergei A. Chekrygin, Daria D. Shafranskaya, Andrey D. Prjibelski, Nataliia V. Katolikova, Raul R. Gainetdinov
Publikováno v:
Cells, Vol 13, Iss 22, p 1910 (2024)
The member of trace-amine associated receptor family, TAAR5 receptor was suggested to recognize tertiary amines, mostly in the olfactory system; however, knocking out the receptor TAAR5 in mice showed an enhancing effect on adult neurogenesis and dop
Externí odkaz:
https://doaj.org/article/52ed6ade49714c86ad072e23f20ca5fd
Autor:
Vsevolod V. Nemets, Ekaterina P. Vinogradova, Vladislav Zavialov, Vladimir P. Grinevich, Evgeny A. Budygin, Raul R. Gainetdinov
Publikováno v:
Biomolecules, Vol 14, Iss 10, p 1280 (2024)
There is a gap in existing knowledge of stress-triggered neurochemical and behavioral adaptations in females. This study was designed to explore the short-term consequences of a single social defeat (SD) on accumbal dopamine (DA) dynamics and related
Externí odkaz:
https://doaj.org/article/45507862d5554f46a5f0581f5a9d67a2
Long-term Intracerebroventricular Administration of Ouabain Causes Motor Impairments in C57Bl/6 Mice
Autor:
Yulia A. Timoshina, Rogneda B. Kazanskaya, Vladislav A. Zavialov, Anna B. Volnova, Alexander V. Latanov, Tatiana N. Fedorova, Raul R. Gainetdinov, Alexander V. Lopachev
Publikováno v:
Анналы клинической и экспериментальной неврологии, Vol 17, Iss 4, Pp 40-51 (2023)
Introduction. Cardiac glycosides are natural ligands of Na+/K+-ATPase, which regulate its activity and signaling. Intracerebroventricular administration of ouabain has been previously shown to induce hyperlocomotion in C57Bl/6 mice via a decrease in
Externí odkaz:
https://doaj.org/article/3880a927326f4a77992a74e92be8f44e
Autor:
Zoia Fesenko, Maria Ptukha, Marcelo M. da Silva, Raquel S. Marques de Carvalho, Vassiliy Tsytsarev, Raul R. Gainetdinov, Jean Faber, Anna B. Volnova
Publikováno v:
Biomedicines, Vol 12, Iss 9, p 2114 (2024)
Background/Objectives: Dopamine dysfunction (DA) is a hallmark of many neurological disorders. In this case, the mechanism of changes in dopamine transmission on behavior remains unclear. This study is a look into the intricate link between disrupted
Externí odkaz:
https://doaj.org/article/97f93109cb8e4a96882d022040ad794b
Autor:
Anastasia N. Vaganova, Alisa A. Markina, Aleksandr M. Belousov, Karina V. Lenskaia, Raul R. Gainetdinov
Publikováno v:
Biomedicines, Vol 12, Iss 7, p 1590 (2024)
Currently, there is a growing amount of evidence for the involvement of dopamine receptors and the functionally related trace amine-associated receptor, TAAR1, in upper intestinal function. In the present study, we analyzed their expression in the du
Externí odkaz:
https://doaj.org/article/cc832b148cfe471bbaa206290f049c4e
Publikováno v:
Biomedicines, Vol 12, Iss 6, p 1263 (2024)
Depression is a common mental illness of great concern. Current therapy for depression is only suitable for 80% of patients and is often associated with unwanted side effects. In this regard, the search for and development of new antidepressant agent
Externí odkaz:
https://doaj.org/article/9c9028b1b7fe42a783335cd225777781
Autor:
Anastasia Belskaya, Natalia Kurzina, Artem Savchenko, Ilya Sukhanov, Arina Gromova, Raul R. Gainetdinov, Anna Volnova
Publikováno v:
Biomedicines, Vol 12, Iss 6, p 1270 (2024)
Playing a key role in the organization of striatal motor output, the dopamine (DA)-ergic system regulates both innate and complex learned behaviors. Growing evidence clearly indicates the involvement of the DA-ergic system in different forms of repet
Externí odkaz:
https://doaj.org/article/d82e06015fed4d9b9952ec12d1c73f38
Publikováno v:
Biomedicines, Vol 12, Iss 4, p 893 (2024)
Trace amines are a separate, independent group of biogenic amines, close in structure to classical monoamine neurotransmitters such as dopamine, serotonin, and norepinephrine that include many products of the endogenous or bacteria-mediated decarboxy
Externí odkaz:
https://doaj.org/article/ce17ac071e46468c8b446cb8136b927a
Autor:
Giancarlo Grossi, Naomi Scarano, Francesca Musumeci, Michele Tonelli, Evgeny Kanov, Anna Carbone, Paola Fossa, Raul R. Gainetdinov, Elena Cichero, Silvia Schenone
Publikováno v:
Molecules, Vol 29, Iss 8, p 1739 (2024)
The search for novel effective TAAR1 ligands continues to draw great attention due to the wide range of pharmacological applications related to TAAR1 targeting. Herein, molecular docking studies of known TAAR1 ligands, characterized by an oxazoline c
Externí odkaz:
https://doaj.org/article/c00b5f6dfd8e4b0f9d0943f5ad4f6b79