Zobrazeno 1 - 10
of 607
pro vyhledávání: '"R. G. Willis"'
Autor:
Henry Cope, Jonas Elsborg, Samuel Demharter, J. Tyson McDonald, Chiara Wernecke, Hari Parthasarathy, Hriday Unadkat, Mira Chatrathi, Jennifer Claudio, Sigrid Reinsch, Pinar Avci, Sara R. Zwart, Scott M. Smith, Martina Heer, Masafumi Muratani, Cem Meydan, Eliah Overbey, Jangkeun Kim, Christopher R. Chin, Jiwoon Park, Jonathan C. Schisler, Christopher E. Mason, Nathaniel J. Szewczyk, Craig R. G. Willis, Amr Salam, Afshin Beheshti
Publikováno v:
Communications Medicine, Vol 4, Iss 1, Pp 1-18 (2024)
Abstract Background Spaceflight poses a unique set of challenges to humans and the hostile spaceflight environment can induce a wide range of increased health risks, including dermatological issues. The biology driving the frequency of skin issues in
Externí odkaz:
https://doaj.org/article/ffa9a91797784258acddd144b101f342
Autor:
Craig R. G. Willis, Marco Calvaruso, Debora Angeloni, Sarah Baatout, Alexandra Benchoua, Juergen Bereiter-Hahn, Daniele Bottai, Judith-Irina Buchheim, Eugénie Carnero-Diaz, Sara Castiglioni, Duccio Cavalieri, Gabriele Ceccarelli, Alexander Chouker, Francesca Cialdai, Gianni Ciofani, Giuseppe Coppola, Gabriella Cusella, Andrea Degl’Innocenti, Jean-Francois Desaphy, Jean-Pol Frippiat, Michael Gelinsky, Giada Genchi, Maria Grano, Daniela Grimm, Alain Guignandon, Raúl Herranz, Christine Hellweg, Carlo Saverio Iorio, Thodoris Karapantsios, Jack van Loon, Matteo Lulli, Jeanette Maier, Jos Malda, Emina Mamaca, Lucia Morbidelli, Andreas Osterman, Aleksandr Ovsianikov, Francesco Pampaloni, Elizabeth Pavezlorie, Veronica Pereda-Campos, Cyrille Przybyla, Petra Rettberg, Angela Maria Rizzo, Kate Robson-Brown, Leonardo Rossi, Giorgio Russo, Alessandra Salvetti, Chiara Risaliti, Daniela Santucci, Matthias Sperl, Kevin Tabury, Sara Tavella, Christiane Thielemann, Ronnie Willaert, Monica Monici, Nathaniel J. Szewczyk
Publikováno v:
npj Microgravity, Vol 10, Iss 1, Pp 1-5 (2024)
Abstract Periodically, the European Space Agency (ESA) updates scientific roadmaps in consultation with the scientific community. The ESA SciSpacE Science Community White Paper (SSCWP) 9, “Biology in Space and Analogue Environments”, focusses in
Externí odkaz:
https://doaj.org/article/c413ab25fccb49618cb6415fe79198c4
Autor:
Purushottam Soni, Hunter Edwards, Taslim Anupom, Mizanur Rahman, Leila Lesanpezeshki, Jerzy Blawzdziewicz, Henry Cope, Nima Gharahdaghi, Daniel Scott, Li Shean Toh, Philip M. Williams, Timothy Etheridge, Nathaniel Szewczyk, Craig R. G. Willis, Siva A. Vanapalli
Publikováno v:
Cells, Vol 12, Iss 20, p 2470 (2023)
Background: Understanding and countering the well-established negative health consequences of spaceflight remains a primary challenge preventing safe deep space exploration. Targeted/personalized therapeutics are at the forefront of space medicine st
Externí odkaz:
https://doaj.org/article/0593e29b7c054cedb21fdca90c1a11b9
Autor:
Craig R. G. Willis, Colleen S. Deane, Ryan M. Ames, Joseph J. Bass, Daniel J. Wilkinson, Kenneth Smith, Bethan E. Phillips, Nathaniel J. Szewczyk, Philip J. Atherton, Timothy Etheridge
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Eccentric (ECC) and concentric (CON) contractions induce distinct muscle remodelling patterns that manifest early during exercise training, the causes of which remain unclear. We examined molecular signatures of early contraction mode-specif
Externí odkaz:
https://doaj.org/article/fe0c75ea1c924a239e9c9b0a609be2ea
Autor:
Ryan M. Ames, Akshay Bhinge, Seema C. Namboori, Patricia Thomas, Lawrence W. Stanton, Alessandro Rosa, Lawrence O. Garrett, Craig R. G. Willis, Sophie Hawkins
Publikováno v:
Stem Cell Reports
Summary Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative condition characterized by the loss of motor neurons. We utilized single-cell transcriptomics to uncover dysfunctional pathways in degenerating motor neurons differentiated from
Maintenance of skeletal muscle mass and function is critical to health and wellbeing throughout the lifespan. However, disuse through reduced physical activity (e.g., sedentarism), immobilisation, bed rest or microgravity has significant adverse effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89dde2ad486f3b1bd510e3dcf0415c31
https://eprints.soton.ac.uk/477909/
https://eprints.soton.ac.uk/477909/
Publikováno v:
British Journal of Surgery. 72:152-152
Autor:
Colleen S, Deane, Bethan E, Phillips, Craig R G, Willis, Daniel J, Wilkinson, Ken, Smith, Nahoko, Higashitani, John P, Williams, Nathaniel J, Szewczyk, Philip J, Atherton, Atsushi, Higashitani, Timothy, Etheridge
Publikováno v:
GeroScience.
Resistance exercise training (RET) can counteract negative features of muscle ageing but older age associates with reduced adaptive capacity to RET. Altered muscle protein networks likely contribute to ageing RET adaptation; therefore, associated pro
Autor:
Timothy Etheridge, Nathaniel J. Szewczyk, Lorna W. Harries, Colleen S. Deane, Bethan E. Phillips, Craig R. G. Willis, Ryan M. Ames, Philip J. Atherton
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle
Journal of Cachexia, Sarcopenia and Muscle, Vol 12, Iss 3, Pp 629-645 (2021)
Journal of Cachexia, Sarcopenia and Muscle, Vol 12, Iss 3, Pp 629-645 (2021)
Background Skeletal muscle atrophy manifests across numerous diseases; however, the extent of similarities/differences in causal mechanisms between atrophying conditions in unclear. Ageing and disuse represent two of the most prevalent and costly atr
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