Zobrazeno 1 - 10
of 55
pro vyhledávání: '"R. G. Sutcliffe"'
Publikováno v:
Endocrine Research. 28:217-229
A polyglutamine repeat in the N-terminus of the rat glucocorticoid receptor shows polymorphism, with variants of Q2RQ5, Q2RQ15-21. We investigated whether these natural polymorphisms affect receptor function, and whether alleles with polyglutamine re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15d0b9f21d684be26729990a0719fe45
https://doi.org/10.1081/erc-120015060
https://doi.org/10.1081/erc-120015060
Autor:
Trevor W. Stone, R. W. Davies, R G Sutcliffe, David Russell, Anthony P. Payne, N.K. Bennett, G Favor, J.M Campbell
Publikováno v:
Journal of Anatomy. 196:629-633
The AS/AGU rat provides an alternative to experimentally produced laboratory models of basal ganglia disorders. This mutant is characterised by disturbances of movement including clumsy gait, whole body tremor, rigidity and difficulty in initiating m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb258b093631cc895be0988a6a9b2217
https://doi.org/10.1046/j.1469-7580.2000.19640629.x
https://doi.org/10.1046/j.1469-7580.2000.19640629.x
Autor:
A J Russell, S McCartin, R G Sutcliffe, A M Wallace, R A Fisher, Berenice B. Mendonca, Ivo J.P. Arnhold, J I Mason, Jennifer Varley
Publikováno v:
Journal of Molecular Endocrinology. 24:75-82
Mutations in HSD3B2, the gene for 3beta-hydroxysteroid dehydrogenase type II (3beta-HSD II) have been detected and activities analysed through the in vitro expression of mutant cDNAs. Two full sibs with male pseudohermaphroditism were found to be dou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe4f8c8a4ad61ed1b20f393996033b11
https://doi.org/10.1677/jme.0.0240075
https://doi.org/10.1677/jme.0.0240075
Investigation of students' cognitive structure in elementary genetics through word association tests
Publikováno v:
Journal of Biological Education. 33:134-141
The word association test is one of the commonest and oldest educational tools for investigating the cognitive structure of learners. In this present study, a word association test was used to map the cognitive structure of areas of elementary geneti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::197a0ad27baf2ccdd493dcd8411496e6
https://doi.org/10.1080/00219266.1999.9655653
https://doi.org/10.1080/00219266.1999.9655653
Autor:
A. G. M. Lam, Anthony P. Payne, R G Sutcliffe, R. W. Davies, James McCulloch, J.M Campbell, N.K. Bennett
Publikováno v:
European Journal of Neuroscience. 10:1963-1967
The AS/AGU mutant rat is characterized by a wide staggering gait and a movement disorder of the hindlimbs. Local cerebral glucose utilization in the brain was investigated using the [14C]2-deoxyglucose autoradiographic technique to map any functional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01e9ed37197fb2900aa2f936cc88c5ff
https://doi.org/10.1046/j.1460-9568.1998.00206.x
https://doi.org/10.1046/j.1460-9568.1998.00206.x
Autor:
J. McGadey, R G Sutcliffe, R. W. Davies, J.E. Byrne, J.M Campbell, David Russell, D.P. Gilmore, D.J. Clarke, Anthony P. Payne
Publikováno v:
Neuroscience Letters. 213:173-176
The sub-strain of Albino Swiss rat (AS/AGU) is a spontaneous mutation characterised by an ungainly, staggering gait, hindlimb rigidity, whole body tremor and (when symptoms are fully developed) difficulty in initiating movement; it exhibits a progres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6864e0531f9223d4b6112ea0836872e5
https://doi.org/10.1016/0304-3940(96)12852-4
https://doi.org/10.1016/0304-3940(96)12852-4
Autor:
R G Sutcliffe, K Vass, K Frank-Raue, Norma Morrison, Martin W. McBride, A J Russell, Elizabeth Boyd, Claude Szpirer, N J Craig
Publikováno v:
Journal of Molecular Endocrinology. 15:167-176
Four hirsute females from a family exhibiting idiopathic dominant hirsutism were examined. Basal blood levels of Δ5 and Δ4 steroids were within the normal range, but ACTH stimulation led to increases in 17-hydroxypregnenolone and dehydroepiandroste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7aa318e634a77905f272c505ab5873a1
https://doi.org/10.1677/jme.0.0150167
https://doi.org/10.1677/jme.0.0150167
Autor:
Christopher J. Kenyon, Karin Klinga-Levan, R G Sutcliffe, G C Inglis, Claude Szpirer, John M. C. Connell
Publikováno v:
Journal of Molecular Endocrinology. 14:303-311
Mouse hepatoma × rat hepatocyte hybrids that segregate rat chromosomes were used to determine the chromosomal location of the rat genes encoding 11 β-hydroxylase and aldosterone synthase (Cyp11b1 and Cyp11b2 respectively). By means of species-speci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f0c0edbd4b020dec4e6341228055bf8
https://doi.org/10.1677/jme.0.0140303
https://doi.org/10.1677/jme.0.0140303
Autor:
Victoria Forster, Bruce A.J. Ponder, Elizabeth Boyd, R G Sutcliffe, A J Russell, Keith Vass, Norma Morrison, Martin W. McBride, Sandra M. Burridge
Publikováno v:
Molecular and Cellular Probes. 9:121-128
Several bands of hydridization are detected when southern blots of human genomic DNA are proved with cDNA of 3 beta-hydroxysteroid dehydrogenase (3 beta-HSD) type I. Two experimental approaches were adopted to estimate the size of the 3 beta-HSD gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31179fc99d6f9c12062347efad59dd7c
https://doi.org/10.1016/s0890-8508(95)80036-0
https://doi.org/10.1016/s0890-8508(95)80036-0
Publikováno v:
Cell Biology International. 19:91-102
We have found that hydrogen peroxide (10(-4)-10(-2) M) rapidly induces microvilli on separate cells and confluent sheets of human retinal pigment epithelium in culture. t-butyl hydroperoxide and sodium arsenite do not induce microvilli. A role for hy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::283713ea053a4547c80377841e3cf564
https://doi.org/10.1006/cbir.1995.1049
https://doi.org/10.1006/cbir.1995.1049