Zobrazeno 1 - 10
of 12
pro vyhledávání: '"R. G. M. van Amsterdam"'
Publikováno v:
British Journal of Clinical Pharmacology. 54:304-308
Aims To investigate the pharmacokinetic and pharmacodynamic interaction of the antithrombotic pentasaccharide fondaparinux (Org31540/SR90107A), given subcutaneously, and oral warfarin in healthy subjects. Methods This study was performed according to
Autor:
J. Necciari, P. Zandberg, R. Cariou, R. G. M. Van Amsterdam, Petitou Maurice, D.G. Meuleman, H.N. Magnani, J. M. Herbert, Jean-C. Lormeau, C. A. A. Van Boeckel
Publikováno v:
Cardiovascular Drug Reviews. 15:1-26
Autor:
P. Zandberg, W. J. Kop, R. G. M. Van Amsterdam, P. van Houwelingen, G.M.T. Vogel, D.G. Meuleman, F. W. J. Van Mensvoort
Publikováno v:
Thrombosis and Haemostasis. 77:183-189
SummaryTwo thrombosis models in rats are described in which mixed type thrombi are formed at arterial and venous flow rates. The models, containing a silk thread in the aorta and vena cava, respectively, were characterised for the activity of three p
Autor:
R. G. M. Van Amsterdam, J.P. He´rault, G.M.T. Vogel, D.G. Meuleman, M. Petitou, J.C. Lormeau, A. Bernat, J.M. Herbert
Publikováno v:
Circulation Research. 79:590-600
SANORG 32701 is a new sulfated pentasaccharide obtained by total chemical synthesis. It is an analogue of the “synthetic pentasaccharide” (SR 90107/ORG 31540), which represents the antithrombin III (AT-III) binding site of heparin. Like SR 90107,
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 15:495-503
Abstract The synthetic pentasaccharide Org 31540/SR 90107A represents the antithrombin III (ATIII) binding region of heparin and accelerates the ATIII-mediated inhibition of coagulation factor Xa. This compound and 15 structural analogues with ATIII
Publikováno v:
Thrombosis and Haemostasis. 69:029-034
SummaryThe mode of action of glycosaminoglycans (GAGs) towards thrombus formation in a rat arteriovenous shunt was studied by simultaneous examination of thrombus weight, platelet consumption and thrombin generation during 45 min of blood circulation
Publikováno v:
British journal of clinical pharmacology. 54(3)
To investigate the pharmacokinetic and pharmacodynamic interaction of the antithrombotic pentasaccharide fondaparinux (Org31540/SR90107A), given subcutaneously, and oral warfarin in healthy subjects.This study was performed according to a randomised,
Autor:
C. A. A. Van Boeckel, R. G. M. Van Amsterdam, P. Westerduin, Peter D. J. Grootenhuis, D.G. Meuleman, Jan E. M. Basten, C.M. Dreef-Tromp
The natural product heparin is an important lead in research on antithrombotics. By molecular modification of a unique heparin fragment new derivatives were discovered. One of them, the synthetic counterpart of the antithrombin III binding pentasacch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f889721f9b3af42cd5f01750c6074fa0
https://doi.org/10.1016/s0165-7208(97)80088-8
https://doi.org/10.1016/s0165-7208(97)80088-8
Autor:
G. J. Blauw, P. van Brummelen, P. Vermeij, P. A. van Zvieten, H. W. C. M. Boddeke, H. N. Doods, P. A. van Zwieten, A. H. Bom, D. J. Duncker, P. D. Verdouw, P. R. Saxena, M. J. A. P. Daemen, H. T. M. Vervoort-Peters, H. H. W. Thijssen, D. Davidesko, H. D. Batink, H. D. Bangik, K. J. van Charldrop, S. F. de Boer, J. L. Slangen, J. van der Gugten, W. S. De Loos, B. Bohus, W. De Jong, D. De Wied, M. A. H. de Zwart, H. van der Goot, H. Timmerman, A. Garritsen, A. P. IJzerman, W. Soudijn, J. B. Heynis, H. W. G. M. Boddeke, B. J. A. Janssen, H. van Essen, H. A. J. Struyker Boudier, J. F. M. Smits, T. J. W. Jap, C. E. J. Ketelaars, J. Bruinvels, M. J. Krielaart, D. M. J. Veenstra, G. J. T. H. Stolze, L. M. L. le Noble, D. W. Slaaf, G. J. Tangelder, H. C. Neijt, I. J. te Duits, J. J. Plomp, H. P. M. Vijverberg, J. A. M. Raaijmakers, R. J. E. van den Eijnde, F. S. Radhakishun, J. C. Stoof, A. H. Mulder, D. H. G. Versteeg, J. M. van Ree, F. A. M. Redegeld, J. Noordhoek, J. M. H. M. Reul, J. A. D. M. Tonnaer, E. R. de Kloet, J. Riezebos, A. de Jonge, C. G. J. Sweep, V. M. Wiegant, F. Th. M. van Amsterdam, M. Haas, J. Zaagsma, R. G. M. van Amsterdam, F. Brouwer, K. J. van Charldorp, R. van de Straat, J. de Vries, N. P. E. Vermeulden, P. L. M. van Giersbergen, J van Harten, RRECM Zeegers, P van Brumnelen, DD Breimer, P. N. M. van Heiningen, E. J. van Hoogdalem, A. G. de Boer, D. D. Breimer, J. van Wijngaarden, H. Wesseling
Publikováno v:
Pharmaceutisch Weekblad. 8:270-278
Publikováno v:
Neurochemistry International. 5:291-297
Brain slices obtained from neocortex, hypothalamus or hippocampus were incubated with [(3)H]histamine and subsequently superfused and exposed to different depolarizing stimuli, viz. high K(+)-concentrations, electrical field stimulation and veratrine