Zobrazeno 1 - 10
of 14
pro vyhledávání: '"R. G. Lapidus"'
Autor:
Y. Liu, O. M. Bah, D. Bollino, K. Caprinolo, J. Zarrabi, S. Philip, R. G. Lapidus, E. T. Strovel, Z. N. Singh, M. E. Kallen, Y. Ning, R. Koka, S. Niyongere, V. H. Duong, M. R. Baer, M. Graveno, A. Emadi
Publikováno v:
HemaSphere, Vol 6, Pp 426-427 (2022)
Externí odkaz:
https://doaj.org/article/965f3cf368dd46a9ab85f8dcbaccfab6
Publikováno v:
The Prostate. 45(4)
Prostate-specific membrane antigen (PSMA) is a glutamate carboxypeptidase that cleaves terminal carboxy glutamates from both the neuronal dipeptide N-acetylaspartylglutamate (NAAG) and gamma-linked folate polyglutamate. The prostate enzyme has activi
Publikováno v:
The Prostate. 44(1)
The polysulfonated napthlyurea suramin has shown significant antitumor activity in patients with hormone-refractory metastatic prostate cancer. The mechanism by which suramin exerts this effect is unknown. In 1993, prostate-specific membrane antigen
Publikováno v:
Journal of mammary gland biology and neoplasia. 3(1)
Hormone responsiveness is a critical determinant of breast cancer progression and management, and the response to endocrine therapy is highly correlated with the estrogen receptor (ER)3 and progesterone receptor (PR) status of tumor cells. Thus, key
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 5(12)
The efficacy of systemic chemotherapy for non-small cell lung cancer (NSCLC) has improved with newer agents. However, the response rates and prolonged survival times achieved by chemotherapy remain modest, and these small gains are obtained at the co
Publikováno v:
The Prostate. 39(1)
The prostate cancer marker prostate-specific membrane antigen (PSM) is highly homologous to the brain enzyme N-acetylated alpha-linked acidic dipeptidase (NAALADase). NAALADase is known to cleave terminal carboxy glutamates from both the neuronal pep
Autor:
R G, Lapidus, S J, Nass, K A, Butash, F F, Parl, S A, Weitzman, J G, Graff, J G, Herman, N E, Davidson
Publikováno v:
Cancer research. 58(12)
Southern analysis has shown that DNA from 25% of primary estrogen receptor (ER) alpha-negative breast tumors displays aberrant methylation at one site within the ER gene CpG island. To examine more sites and increase sensitivity, we developed a methy
Publikováno v:
Cancer treatment and research. 94
Autor:
R G, Lapidus, A T, Ferguson, Y L, Ottaviano, F F, Parl, H S, Smith, S A, Weitzman, S B, Baylin, J P, Issa, N E, Davidson
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 2(5)
Hormonal factors have a profound influence on the development, treatment, and outcome of breast cancer. The absence of steroid hormone receptors is highly correlated with resistance to antihormonal treatments. Work in cultured human breast cancer cel
Autor:
J R, Graff, J G, Herman, R G, Lapidus, H, Chopra, R, Xu, D F, Jarrard, W B, Isaacs, P M, Pitha, N E, Davidson, S B, Baylin
Publikováno v:
Cancer research. 55(22)
Expression of the Ca(2+)-dependent, homotypic cell:cell adhesion molecule, E-cadherin (E-cad), suppresses tumor cell invasion and metastasis in experimental tumor models. Decreased E-cad expression is common in poorly differentiated, advanced-stage c