Zobrazeno 1 - 10
of 10
pro vyhledávání: '"R. G. L. Pullen"'
Publikováno v:
Life Sciences. 58:2125-2135
These experiments have investigated selenium movement between blood and CNS in anaesthetised rats. Each animal was surgically anaesthetised and the left femoral blood vessels cannulated for blood withdrawal and solute infusion. Each rat received 75-s
Publikováno v:
Neurochemical Research. 20:1141-1146
These experiments have investigated selenium movement between blood and the CNS in anaesthetized rats. Each animal was anaesthetized and the left femoral blood vessels cannulated for blood withdrawal and solute infusion. Each rat received 75-Se as so
Publikováno v:
Neurochemical Research. 17:1181-1185
Silicon (Si) is an essential trace element normally present in brain and cerebrospinal fluid, although the mechanism by which it enters and distributes in brain is largely unknown. Due to the short radioactive half-life of 31Si (156 min) we have inve
Autor:
Christopher Morris, J.M. Candy, R. G. L. Pullen, C.A. Bloxham, Geoffrey A. Taylor, A. Gocht, J.A. Edwardson, Arthur E. Oakley, A.B. Keith
Publikováno v:
Journal of Inorganic Biochemistry. 47:257-265
The anatomical and cellular distribution of non-haem iron, ferritin, transferrin, and the transferrin receptor have been studied in postmortem human brain and these studies, together with data on the uptake and transport of labeled iron, by the rat b
Publikováno v:
Journal of Neurochemistry. 59:300-306
Brain uptake of iron-59 and iodine-125-labelled transferrin from blood in the adult rat has been investigated using graphical analysis to determine the blood-brain barrier permeability to these tracers in experiments that lasted between 5 min and 8 d
Publikováno v:
Neurochemical Research. 15:1003-1008
Zinc is essential for normal growth, development and brain function although little is known about brain zinc homeostasis. Therefore, in this investigation we have studied 65Zn uptake from blood into brain and other tissues and have measured the bloo
Publikováno v:
Neurochemical research. 17(8)
Zinc is essential for normal development and function of the CNS although much is to be learned about brain Zn homeostasis. In these experiments adult male Wistar rats within the weight range 500-600 g were used. Ventriculo-cisternal perfusion was pe
Publikováno v:
Journal of neurochemistry. 56(2)
Zinc is essential for the normal development and function of the CNS, although little is known about brain zinc homeostasis. Therefore, in this investigation we have studied 65Zn uptake by brain from blood and have measured the blood-brain barrier pe
Publikováno v:
Journal of neurochemistry. 55(1)
Evidence of a link between aluminium and Alzheimer's disease, parkinsonism-dementia of Guam, and dialysis encephalopathy raises questions regarding the role of this element in the pathogenesis of these conditions. Therefore, we have investigated the
Autor:
O. J. Hodgson, R. G. L. Pullen
Publikováno v:
Journal of Pharmacy and Pharmacology. 39:863-864
Interest in the actions of the peptide cholecystokinin (CCK) has led to the design and synthesis of several non-peptide CCK antagonists, the most recent being that produced by Merck Sharp & Dohme and designated L-364, 718. This can be viewed as modif