Zobrazeno 1 - 10
of 129
pro vyhledávání: '"R. G. Alken"'
Autor:
R. G. Alken, J. Meyer, Norbert Treese, Susanne Mohr-Kahaly, Diefenbach C, S. Rhein, Raimund Erbel
Publikováno v:
DMW - Deutsche Medizinische Wochenschrift. 112:1163-1169
Effect and tolerance of the oral phosphodiesterase inhibitor Enoximone was tested in 14 patients with advanced cardiac failure (New York Heart Association groups II-IV). During a mean observation period of 40 weeks there were four deaths; one patient
Autor:
Rossen Koytchev, V Vlahov, E. Rehak, U. Thyroff-Friesinger, R.-G. Alken, Valentin Kirkov, R. Kaneva
Publikováno v:
European Journal of Clinical Pharmacology. 54:469-474
The aim of the present paper was to compare the pharmacokinetics of metoprolol in homozygous Caucasian volunteers for the wild-type CYP2D6 allele (CYP2D6*1/CYP2D6*1) and heterozygous (CYP2D6*1/CYP2D6*4) Caucasians.Thirty-six unrelated healthy male Ca
Publikováno v:
Agents and Actions. 43:48-52
An open trial was conducted in 22 in-patients with classic or definite rheumatoid arthritis (RA) and 17 in-patients with M. Bechterew with the aim to investigate the effect of increasing concentrations of piroxicam in vivo on the platelet aggregation
Publikováno v:
European archives of psychiatry and clinical neuroscience. 255(1)
Efficacy and tolerability of Hypericum LI 160 was compared to fluoxetine and placebo in mild to moderate Major Depression (DSM-IV) in a 4-week randomized, double-blind trial. One hundred and sixty-three outpatients from 15 general practitioner center
Autor:
B Gawronska-Szklarz, M van der Meer, N Bacratcheva, Rossen Koytchev, B Giesel, J Wojcicki, A Mrozikiewiczs, R G Alken, V Vlahov
Publikováno v:
International journal of clinical pharmacology and therapeutics. 41(3)
Background The aim of the present trial was to evaluate the efficacy of a combined product in the treatment of common cold and to examine the contribution of the separate components. In the published literature there is conflicting data on the effica
Publikováno v:
Pain. 67(2-3)
The efficacy and safety of oral tolperisone hydrochloride (Mydocalm) in the treatment of painful reflex muscle spasm was assessed in a prospective, randomized, double-blind, placebo-controlled trial. A total of 138 patients, aged between 20 and 75 ye
Publikováno v:
European journal of clinical pharmacology. 51(2)
Objective: The present study was conducted with the aim of investigating the absolute bioavailability of fluphenazine in healthy volunteers after administration of immediate and slow release oral formulations. Methods: The oral dose was 12 mg fluphen
Publikováno v:
European journal of clinical pharmacology. 50(4)
The present study was done to investigate the effect of food on the bioavailability of diprafenone.The most important pharmacokinetic parameters (Cmax, t1/2, AUC) and the relative oral availability of a solid oral preparation of racemic diprafenone w
Publikováno v:
European journal of clinical pharmacology. 50(1-2)
This study was conducted to investigate the effect of diprafenone on the steady-state pharmacokinetics of digoxin. Twelve healthy men, all rapid hydroxylators of debrisoquine, received digoxin (0.5 mg per day over 7 days with a loading dose of 2 x 1