Zobrazeno 1 - 10
of 76
pro vyhledávání: '"R. G., Paronikyan"'
Publikováno v:
Эпилепсия и пароксизмальные состояния, Vol 15, Iss 4, Pp 318-325 (2023)
Objective: to evaluate an effectiveness of new nitrogen-containing compounds for alleviating epileptiform conditions in animal experimental study, and conduct molecular modeling of a new neurotropic drug.Material and methods. The anticonvulsant and p
Externí odkaz:
https://doaj.org/article/a63b983947c0454999f8c6c6f744fa0e
Autor:
R. G. Paronikyan, M. N. Avagyan, A. A. Harutyunyan, G. G. Avakyan, S. A. Litvinova, T. A. Voronina
Publikováno v:
Эпилепсия и пароксизмальные состояния, Vol 11, Iss 3, Pp 244-254 (2019)
Aim: to study the anticonvulsant and psychotropic activities and side effects of pufemid, pyrathidine and compound N3012 developed at the Institute of Fine Organic Chemistry of the National Academy of Sciences.Materials and methods. Anticonvulsant ac
Externí odkaz:
https://doaj.org/article/a0d17673a8af4f6b9d521d33d0a95144
Autor:
R. G. Paronikyan, R. Sh. Sargsyan, M. N. Avagyan, M. S. Grigoryan, A. L. Kostanyan, N. D. Paronikyan, V. M. Avagyan, L. S. Vardanyan
Publikováno v:
Эпилепсия и пароксизмальные состояния, Vol 11, Iss 2, Pp 142-152 (2019)
Aim. This study was aimed to test the instrumental complex called «Bioscope» for its ability to determine the optimal dose of the anticonvulsant drugs lamotrigine and topiramate in the treatment of epileptiform states.Materials and methods. The exp
Externí odkaz:
https://doaj.org/article/9ef69441a69d4b63b60c5ee8466ff000
Autor:
S. L. Kocharov, H. A. Panosyan, I. A. Jaghatspanyan, I. M. Nazaryan, R. G. Paronikyan, H. G. Hakobyan, H. M. Stepanyan, R. V. Paronikyan
Publikováno v:
Pharmaceutical Chemistry Journal. 56:1443-1450
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ce61265ebc0f3d41a1f89f5cb118d4d
https://doi.org/10.1007/s11094-023-02810-7
https://doi.org/10.1007/s11094-023-02810-7
Publikováno v:
Эпилепсия и пароксизмальные состояния, Vol 9, Iss 4, Pp 86-95 (2018)
The aim of the study is the assessment of possibility of using «Bioscope» device to detect the direction of changes in the integrative state of organism of rats under the influence of analeptic and convulsive agent of corazole, and known anticonvul
Externí odkaz:
https://doaj.org/article/0e84e7a500bc4dbebb4ad7cc20f8ad9c
Autor:
R. G. Paronikyan
Publikováno v:
Эпилепсия и пароксизмальные состояния, Vol 9, Iss 3, Pp 39-46 (2017)
Objective: to study the anticonvulsant and psychotropic effects of novel benzothienopyrimidine derivatives and rationalize their use for medical practice.Materials and methods. The anticonvulsant effects were studied by using the models of murine sei
Externí odkaz:
https://doaj.org/article/64e8b4e3d9ab4bacb4f82a5237ed3ec4
Autor:
V. V. Dabaeva, M. R. Baghdasaryan, R. G. Paronikyan, I. M. Nazaryan, H. G. Hakobyan, L. S. Hunanyan, E. G. Paronikyan, Sh. Sh. Dashyan
Publikováno v:
Russian Journal of Bioorganic Chemistry. 48:125-134
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83a4afbe414542405850008e9821ff49
https://doi.org/10.1134/s1068162022010034
https://doi.org/10.1134/s1068162022010034
Autor:
V. V. Dabaeva, A. G. Akopyan, Sh. Sh. Dashyan, R. G. Paronikyan, I. M. Nazaryan, M. R. Bagdasaryan, E. G. Paronikyan
Publikováno v:
Pharmaceutical Chemistry Journal. 54:707-713
2-Oxo-2,5,6,7-tetrahydro-3-cyano-1H-cyclopenta[b]pyridine was used as the starting point to develop an accessible synthesis of condensed cyclopentanopyrido[3',2':4,5]thieno[3,2-d]pyrimidine derivatives. The neurotropic activity of these compounds was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f27aa3e5f8e81d45789f98a47ec5b09c
https://doi.org/10.1007/s11094-020-02259-y
https://doi.org/10.1007/s11094-020-02259-y
Publikováno v:
Russian Journal of Organic Chemistry. 56:422-428
Conditions for the Gewald synthesis of 2-amino-5,5-dimethyl-4,7-dihydro-5H-thieno[2,3-c]pyrans from 2,2-dimethyltetrahydropyran-4-ones have been optimized, and the yields have been improved. A procedure has been developed for the synthesis of new pyr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dcec51237465c3fd3b1b8e7357527cc9
https://doi.org/10.1134/s1070428020030094
https://doi.org/10.1134/s1070428020030094
Autor:
I. M. Nazaryan, R. G. Paronikyan, Samvel N. Sirakanyan, E. K. Akopyan, A. A. Ovakimyan, A. G. Akopyan
Publikováno v:
Pharmaceutical Chemistry Journal. 53:495-499
Methods were developed for synthesizing new substituted piperazine derivatives from chloropyrano- [3,4-c]pyridines. Pharmacological screening of the synthesized compounds used the well-known corazole antagonism and open field tests. The rotating rod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f54b11ed34cbaed5dac3870a5a8b66e
https://doi.org/10.1007/s11094-019-02026-8
https://doi.org/10.1007/s11094-019-02026-8