Ketogenic Diet with Concurrent Chemoradiation in Head and Neck Squamous Cell Carcinoma: Preclinical and Phase 1 Trial Results

Autor: Elizabeth Loth, Carryn M. Anderson, Douglas R. Spitz, Samuel N. Rodman, Daniel C. Ma, Melissa A. Fath, Andrew B. Davis, Logan Ahmann, Visarut Buranasudja, Kellie L. Bodeker, Michael L. McCormick, Andrean L. Simons, Wenqing Sun, Bryan G. Allen, Jessica Parkhurst, Kayla R. Follmer, John M. Buatti

Publikováno v: Radiat Res

Ketogenic diets (KD) are high in fat and low in carbohydrates, forcing cells to utilize mitochondrial fatty acid oxidation for energy production. Since cancer cells demonstrate increased mitochondrial oxidative stress relative to normal cells, we hyp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::946a63f574aaad7b1bf6b3a241482310
https://doi.org/10.1667/rade-20-00150.1

Envisioning the fascist 'reality'

Autor: Carl R. Follmer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6342281c27a27b421c9d22b32fe4ac34
https://doi.org/10.17077/etd.og8izfur

Abstract LB-252: Ketogenic diet with concurrent chemoradiation in head and neck squamous cell carcinoma: Pre-clinical and phase I trial results

Autor: Visarut Buranasudja, Douglas R. Spitz, Daniel Ma, Samuel N. Rodmann, Kellie L. Bodeker, Carryn M. Anderson, Bryan G. Allen, Jessica Parkhurst, John M. Buatti, Melissa A. Fath, Kayla R. Follmer, Michael McCormack, Andrew B. Davis

Publikováno v: Cancer Research. 78:LB-252

Purpose: A ketogenic diet (KD) is a high fat, low carbohydrate diet that forces cells to utilize mitochondrial fatty acid oxidation for energy production. It has been previously shown that cancer cells have defects in mitochondrial oxidative metaboli

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::69562c5fa95cbb6665053e32587eb537
https://doi.org/10.1158/1538-7445.am2018-lb-252

Relapse rates and enhancing lesions in a phase II trial of natalizumab in multiple sclerosis

Autor: D. Dodick, K. Bruining, Catherine M. Dalton, W. Morrison, D. Derrington, A. Bowling, J. Adams, J. Hebert, S. Curtis, Minhua Yang, Gareth J. Barker, R. E. Kramer, J. P. Kelly, D. G. MacManus, Shôn Lewis, L. Costley, K. Bracht, E. Drexler, M. Malikowski, R. S. Murray, Clive Hawkins, K. Markopoulou, David P. Richman, William A. Sheremata, K. Nelson, M. Yeung, R. Wolintz, I. Rozentsvit, Joel Oger, Luanne M. Metz, Kathleen Healey, Jonathan L. Carter, Zahid Latif, J. Trotter, C. Mathews, C. Wallace, Jinan Al-Omaishi, Katherine Riester, Todd L. Richards, C. Webb, B. Harwick, Thomas E. Conturo, C. Gibson, E. Prenger, G. Foster, J. Forsyth, Michael Kaufman, L D Blumhardt, D. A H Cross, J. Curlis, James D. Bowen, C. Coombs, V. Orpe, Mark A. Agius, Omar Khan, C. Martinez, J. Takata, C. Graves, S. Putman, J. Scott, A. Diedrich, L. Capolino, J. Leitch, Per Soelberg Sørensen, M. Cochran, M. Buonocore, P. English, Christopher F. O'Brien, M. J. Keilson, A. Schneider, A. Miller, George Rice, Alexandros Tselis, C. Middleditch, S. Dombrowski, L. Wang, H. Oltazewska, J. Lauber, J. Heuser, H. Lew, Virginia Devonshire, M. Zvartau-Hinds, M. Burke, D. Patry, Paul O'Connor, M. Chang, Katherine A. Miszkiel, Lauren Seeberger, David W. Bates, L. Sciarra, E. Riddle, Robert P. Lisak, Michael Panzara, David Miller, R. Follmer, T. Jaspen, M. Din, T. Pepple, Christina Caon

Publikováno v: Multiple Sclerosis Journal. 11:568-572

Background: Natalizumab, a humanized monoclonal IgG4 antibody, is an a4-integrin antagonist, which inhibits the migration of inflammatory cells into the central nervous system, a key pathogenic mechanism in multiple sclerosis (MS). In a six month, ph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38665639a011a220df8600c7e84283b2
https://doi.org/10.1191/1352458505ms1205oa

Modern, Sangamon and Yarmouth soil development in loess of unglaciated southwestern Illinois

Autor: Randall E. Hughes, Peter Solheid, David A. Grimley, Leon R. Follmer

Publikováno v: Quaternary Science Reviews. 22:225-244

The Thebes Section in unglaciated southwestern Illinois contains a well preserved ∼500 kyr loess–paleosol sequence with four loesses and three interglacial soils. Various magnetic, mineralogical, and elemental properties were analyzed and compare

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::53721fd6372d7cbbc6fdf4246d32ad3a
https://doi.org/10.1016/s0277-3791(02)00039-2