Zobrazeno 1 - 10
of 21
pro vyhledávání: '"R. F. W. Moulds"'
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 22:17-20
1. In order to investigate further whether the increased sensitivity to inhibition by nifedipine of the responses to noradrenaline of aortae from spontaneously hypertensive stroke-prone (SHRSP) rats is related to the development of the hypertension,
Autor:
R. F. W. Moulds, V. Iwanov
Publikováno v:
British Journal of Clinical Pharmacology. 31:47-54
1. The effects of the voltage dependent calcium channel blocking agent nifedipine, and of a calcium free bathing medium, on the responses of human blood vessels obtained postmortem to various agonists have been compared with those of the rat aorta. T
Autor:
David P Tognarini, R. F. W. Moulds
Publikováno v:
European journal of pharmacology. 322(1)
To simultaneously and rapidly measure intracellular Ca2+ concentration ([Ca2+]i) and contraction in vascular smooth muscle, the Ca2+ fluorophore, fura-2/acetoxymethyl ester, was incorporated into an intact sample of rat aorta. Noradrenaline produced
Autor:
R. F. W. Moulds
Publikováno v:
Australian Prescriber. 27:136-137
It is an article of faith in modern medicine that we need new drugs to treat most disorders. This belief has...
Publikováno v:
Anaesthesia and intensive care. 22(4)
Publikováno v:
European Journal of Pharmacology. 183:1743
Autor:
S. Lipe, R. F. W. Moulds
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 12:319-323
SUMMARY 1. Digital arteries, removed at autopsy from 12 hypertensives and 11 normotensives, have been compared in vitro for the calcium dependence of contractures produced by potassium chloride and noradrenaline, and the potency of verapamil to antag
Publikováno v:
Clinical and Experimental Hypertension. Part B: Hypertension in Pregnancy. 1:511-529
In vivo platelet activation by circulating immune complexes has been suggested as one of the underlying mechanisms in preeclampsia. Using a modification of the polyethylene glycol protein-A immune complex assay, immune complexes were found in excess
Autor:
M. J. Stevens, R. F. W. Moulds
Publikováno v:
Journal of Cardiovascular Pharmacology. 4:S129-S133
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 14:379-384
SUMMARY 1. The post-receptor mechanisms of α1 and α2-adrenoceptor subtypes in guinea-pig aorta and human digital arteries have been explored. 2. Nifedipine antagonized contractile responses of human digital arteries to TL99 and methoxamine to a sim