Zobrazeno 1 - 10
of 12
pro vyhledávání: '"R. F. R. Brown"'
Autor:
Charles Masey, R. F. R. Brown, John Jenner, Thomas Mann, Adam N. Smith, Paul Rice, BJ Jugg, Janet Platt
Publikováno v:
Military Medicine. 174:1287-1294
Toxic industrial chemicals e.g., phosgene, are widely used as reactive intermediates in industrial processes. Inhalation exposure to these chemicals can result in life-threatening acute lung injury (ALI), to which no specific antidote exists. This st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc7cd19b4ea12c923d6141f5719589cc
https://doi.org/10.7205/milmed-d-09-00050
https://doi.org/10.7205/milmed-d-09-00050
Autor:
DA Parkhouse, John Jenner, Paul Rice, R. F. R. Brown, TM Mann, BJ Jugg, Christopher Grainge, A.J. Smith
Publikováno v:
Journal of the Royal Army Medical Corps. 155:105-109
To examine the effectiveness of nebulised salbutamol in the treatment of phosgene induced acute lung injury.Using previously validated methods, 12 anaesthetised large white pigs were exposed to phosgene (Ct 1978 +/- 8 mg min m(-3)), established on me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc9d90d11891bd19d126d38ed3b711d8
https://doi.org/10.1136/jramc-155-02-05
https://doi.org/10.1136/jramc-155-02-05
Autor:
S.J. Fairhall, Bronwen Jugg, J Jenner, A.J. Smith, R. F. R. Brown, Alfred M. Sciuto, T. M. Mann
Publikováno v:
Toxicology Mechanisms and Methods. 18:355-362
Although normally regarded as a vesicant, inhalation of sulphur mustard (HD) vapor can cause life-threatening lung injury for which there is no specific treatment. Novel therapies for HD-induced lung injury are best investigated in an in vivo model t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bbe41814f461177ef6a69f2f302612f
https://doi.org/10.1080/15376510701623383
https://doi.org/10.1080/15376510701623383
Autor:
BJ Jugg, Fraser M. Harban, John Jenner, R. F. R. Brown, Christopher E. Kenward, Jan Platt, DA Parkhouse, Paul Rice, Adam J. Smith
Publikováno v:
Military medicine. 172(3)
Phosgene is a chemical widely used in the plastics industry and has been used in warfare. It produces a life-threatening pulmonary edema within hours of exposure, to which no specific antidote exists. This study aims to examine the pathophysiological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f69100eecbe767a5d42d6b6db48d049c
https://pubmed.ncbi.nlm.nih.gov/17436775
https://pubmed.ncbi.nlm.nih.gov/17436775
Publikováno v:
Journal of plastic, reconstructiveaesthetic surgery : JPRAS. 59(10)
The chemical warfare agent, sulphur mustard (SM), is a potent blistering agent in man. Skin exposure can produce partial-thickness burns which take up to three months to heal. The aim of this study was to investigate the use of early laser ablation a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8174912c5e0693b2567ea569bb573128
https://pubmed.ncbi.nlm.nih.gov/16996434
https://pubmed.ncbi.nlm.nih.gov/16996434
Autor:
D. E. White, R. F. R. Brown
Publikováno v:
International journal of experimental pathology. 78(4)
Ricin is one of a group of structurally related plant lectins and is extracted from the seeds of the Castor Oil plant, Ricinus communis. Groups of rats were exposed to ricin aerosol by inhalation, total LCt1 = 11.21 mg.min.m−3 (an approximate LCt30
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85fdb6e0701849e2a7a4ca4721254575
https://pubmed.ncbi.nlm.nih.gov/9505938
https://pubmed.ncbi.nlm.nih.gov/9505938
Autor:
R. F. R. Brown, P. Rice
Sulphur mustard (HD) or "mustard gas' is a potent vesicant chemical warfare agent whose biological effects in man have been well documented. The histopathological features of the developing cutaneous HD lesion in female Yucatan minipigs up to 24 hour
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e73e454e003c495e8c24b3df4121c28c
https://europepmc.org/articles/PMC2694520/
https://europepmc.org/articles/PMC2694520/
Publikováno v:
Prehospital and Disaster Medicine. 17:S61-S61
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5aff2620b6bc679d2084b9bfafc7ee56
https://doi.org/10.1017/s1049023x00010499
https://doi.org/10.1017/s1049023x00010499
Autor:
P Rice, R F R Brown
Publikováno v:
International Journal of Experimental Pathology. 80:59
Studies performed in the past in our laboratory have detailed the development of sulphur mustard lesions in the domestic, white pig using small glass chambers to achieve saturated vapour exposure under occluded conditions. We have now used this exper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caa303538c8bcdc2235f884cc74dcefa
https://doi.org/10.1046/j.1365-2613.1999.00099.x
https://doi.org/10.1046/j.1365-2613.1999.00099.x
Publikováno v:
Archives of Toxicology. 62:123-132
Mice, rats and guinea pigs were exposed to the smoke produced by ignition of a zinc oxide/hexachloroethane pyrotechnic composition, 1 h/day, 5 days/week, at three different dose levels, together with controls. The animals received 100 exposures excep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a59855ec2c68e6d4d5f27d0dbd3026c6
https://doi.org/10.1007/bf00570130
https://doi.org/10.1007/bf00570130