Zobrazeno 1 - 10
of 1 520
pro vyhledávání: '"R. F. Green"'
Autor:
Grant S. Mannino, Tabitha R. F. Green, Sean M. Murphy, Kevin D. Donohue, Mark R. Opp, Rachel K. Rowe
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract A significant effort in biomedical sciences has been made to examine relationships between sex and the mechanisms underlying various disease states and behaviors, including sleep. Here, we investigated biological sex differences in sleep usi
Externí odkaz:
https://doaj.org/article/f0b4ef0d0ce4494d8c1316437df74ec1
Autor:
Tabitha R. F. Green, Sean D. Carey, Grant Mannino, John A. Craig, Rachel K. Rowe, Mark R. Zielinski
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
Traumatic brain injury (TBI) can induce dysregulation of sleep. Sleep disturbances include hypersomnia and hyposomnia, sleep fragmentation, difficulty falling asleep, and altered electroencephalograms. TBI results in inflammation and altered hemodyna
Externí odkaz:
https://doaj.org/article/565034f2b9bc49fe971e413f709e1877
Autor:
Erskine Chu, Richelle Mychasiuk, Tabitha R. F. Green, Akram Zamani, Larissa K. Dill, Rishabh Sharma, April L. Raftery, Evelyn Tsantikos, Margaret L. Hibbs, Bridgette D. Semple
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
IntroductionSevere traumatic brain injury (TBI) is the world’s leading cause of permanent neurological disability in children. TBI-induced neurological deficits may be driven by neuroinflammation post-injury. Abnormal activity of SH2 domain-contain
Externí odkaz:
https://doaj.org/article/0202688fd3b94e7cb9056756e32b300f
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Microglial morphology is used to measure neuroinflammation and pathology. For reliable inference, it is critical that microglial morphology is accurately quantified and that results can be easily interpreted and compared across studies and l
Externí odkaz:
https://doaj.org/article/f6eecfe4c6104c7292a1a1ef34df8243
Autor:
Tabitha R. F. Green, Sean M. Murphy, Maria P. Moreno-Montano, Etienne Audinat, Rachel K. Rowe
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
The microglial response to a pathological microenvironment is hallmarked by a change in cellular morphology. Following a pathological stimulus, microglia become reactive and simultaneously divide to create daughter cells. Although a wide array of mic
Externí odkaz:
https://doaj.org/article/6fb88f05423a45ecba45eaa9a738660c
Publikováno v:
Frontiers in Neurology, Vol 12 (2022)
Few translational studies have examined how age-at-injury affects the glial response to traumatic brain injury (TBI). We hypothesized that rats injured at post-natal day (PND) 17 would exhibit a greater glial response, that would persist into early a
Externí odkaz:
https://doaj.org/article/dffbc0cb5fb948589181a26ff1daf90b
Autor:
Rachel K. Rowe, Tabitha R. F. Green, Katherine R. Giordano, J. Bryce Ortiz, Sean M. Murphy, Mark R. Opp
Publikováno v:
Biology, Vol 11, Iss 8, p 1241 (2022)
Microglia play a critical role in the neuroimmune response, but little is known about the role of microglia in sleep following an inflammatory trigger. Nevertheless, decades of research have been predicated on the assumption that an inflammatory trig
Externí odkaz:
https://doaj.org/article/f3ec24e27bd94f018a804927b7587dad
Autor:
Brittany Gerald, J. Bryce Ortiz, Tabitha R. F. Green, S. Danielle Brown, P. David Adelson, Sean M. Murphy, Rachel K. Rowe
Publikováno v:
Biology, Vol 11, Iss 4, p 600 (2022)
The objective of this study was to determine the prevalence of sleep-wake disturbances (SWD) following pediatric traumatic brain injury (TBI), and to examine characteristics of TBI and patient demographics that might be predictive of subsequent SWD d
Externí odkaz:
https://doaj.org/article/0cd8f62c5b594868b5e9dbf4a8a65c99
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Traumatic brain injury (TBI) and Alzheimer’s disease (AD) are diseases during which the fine-tuned autoregulation of the brain is lost. Despite the stark contrast in their causal mechanisms, both TBI and AD are conditions which elicit a neuroinflam
Externí odkaz:
https://doaj.org/article/13f602016b8b425bb0a7b4036e308ea9
Autor:
Christopher R. Apostol, Kelsey Bernard, Parthasaradhireddy Tanguturi, Gabriella Molnar, Mitchell J. Bartlett, Lajos Szabò, Chenxi Liu, J. Bryce Ortiz, Maha Saber, Katherine R. Giordano, Tabitha R. F. Green, James Melvin, Helena W. Morrison, Lalitha Madhavan, Rachel K. Rowe, John M. Streicher, Michael L. Heien, Torsten Falk, Robin Polt
Publikováno v:
Frontiers in Drug Discovery. 1
There is an unmet clinical need for curative therapies to treat neurodegenerative disorders. Most mainstay treatments currently on the market only alleviate specific symptoms and do not reverse disease progression. The Pituitary adenylate cyclase-act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c196051e4fec6350d54a9817d75cf236
https://doi.org/10.3389/fddsv.2021.818003
https://doi.org/10.3389/fddsv.2021.818003