Zobrazeno 1 - 10 of 51 pro vyhledávání: '"R. Endele"'
1
Kinetics of canrenone after single and multiple doses of spironolactone
Autor: U. Abshagen, K. Koch, E Besenfelder, R. Endele, B. Neubert
Publikováno v: European Journal of Clinical Pharmacology. 16:255-262
In Study I 20 normal volunteers received a single oral dose of spironolactone 100 mg. In Study II a further 20 normal volunteers were given first spironolactone 100 mg b.i.d. and subsequently spironolactone 100 mg once a day for a further 4 days. In
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::219ff5b208e8eb7eb598bea3ee292d6a
https://doi.org/10.1007/bf00608404
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3
MS/MS in pharmacokinetic studies
Autor: M. Senn, R. Endele
Publikováno v: International Journal of Mass Spectrometry and Ion Physics. 48:81-84
Two examples of quantitative drug concentration measurements in biological matrices are presented using (GC)-MS-MS techniques with a triple stage quadrupole mass spectrometer in the multiple reaction monitoring mode. Advantages over the well establis
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3c6df184eb40daa2c2e64e8db54df7b7
https://doi.org/10.1016/0020-7381(83)87033-8
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7
Quantifizierung von Glyceroltrinitrat und Nitraten des Isosorbids in Humanserum mittels Gaschromatographie
Autor: R. Endele, G. Menke
Publikováno v: Nitrattherapie heute ISBN: 9783528079321
Die Konzentrationsbestimmung von organischen Nitraten im Blut stellt hohe Anforderungen an die analytischen Methoden. Die zu erwartenden Serumkonzentrationen von Isosorbiddinitrat (ISDN), Isosorbid-2-mononitrat (IS-2-MN) und Isosorbid-5-mononitrat (I
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::49f4f09b2d987e5e0020b05444cf1153
https://doi.org/10.1007/978-3-322-87597-6_6
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8
Pharmacokinetics of intravenous and oral isosorbide - 5 - mononitrate
Autor: B. Kaufmann, U. Abshagen, R. Endele, G. Betzien
Publikováno v: European journal of clinical pharmacology. 20(4)
The pharmacokinetics of isosorbide-5-mononitrate (IS-5-MN) has been studied in two groups of healthy volunteers after oral (n = 20) and intravenous (n = 11) administration of 20 mg, which had previously been proved to be as effective as 20 mg sustain
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d74ddf675facd97e5bb0e52d3cc8a76
https://pubmed.ncbi.nlm.nih.gov/7308280
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9
Pharmacokinetics and metabolism of isosorbide-dinitrate after intravenous and oral administration
Autor: B. Kaufmann, R. Endele, U. Abshagen, Neugebauer G, G. Betzien
Publikováno v: European journal of clinical pharmacology. 27(6)
The bioavailabilities of a conventional and two slow release 20 mg isosorbide dinitrate (ISDN) formulations were compared after oral administration in a three way cross-over study in 8 male volunteers. In a further group of 6 male volunteers the phar
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7078c960347f84b30122d7ab0c0714b
https://pubmed.ncbi.nlm.nih.gov/3987768
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