Zobrazeno 1 - 10
of 393
pro vyhledávání: '"R. Eisenman"'
Autor:
John R. Doedens, Beverly J Castner, Guixian Jin, Susan W. Sunnarborg, Roy A. Black, R. Cowling, Jennifer L. Slack, Richard S. Johnson, Keith Charrier, Ray Paxton, Duke Virca, David C. Lee, Lin Guo, Alison Wallace, Jacques J. Peschon, Rajeev M Mahimkar, June R. Eisenman
Publikováno v:
Biochemical Society Symposia. 70:39-52
Tumour necrosis factor α (TNFα)-converting enzyme (TACE/ADAM-17, where ADAM stands for a disintegrin and metalloproteinase) releases from the cell surface the extracellular domains of TNF and several other proteins. Previous studies have found that
Autor:
Jeff Fitzner, Erik Jacobson, Lin Guo, Alison Wallace, Min Shen, June R. Eisenman, Richard S. Johnson
Publikováno v:
Molecular & Cellular Proteomics. 2:315-324
Inexpensive methods were developed for isolating and isotopically labeling tryptic peptides that contain either cysteine or methionine. After covalently capturing cysteine-containing peptides with pyridyl disulfide reactive groups on agarose beads, e
Autor:
Dave Lynch, Kenneth H. Grabstein, Dean K. Pettit, Courtney Beers, Wayne R. Gombotz, Jeff Yost, Ray Paxton, Timothy P. Bonnert, Bob Miller, June R. Eisenman, Subhashini Srinivasan
Publikováno v:
Journal of Biological Chemistry. 272:2312-2318
Interleukin (IL)-15 is a multifunctional cytokine that shares many biological activities with IL-2. This functional overlap, as well as receptor binding subunits shared by IL-15 and IL-2, suggests tertiary structural similarities between these two cy
Autor:
Lisabeth Johnson, June R. Eisenman, Courtney Beers, Subhashini Srinivasan, Judith G. Giri, Minoo Ahdieh, Dirk M. Anderson, Jane S. Richardson, Kurt D. Shanebeck, Kenneth H. Grabstein, James D. Watson, Mark R. Alderson, Victor Fung, Michael A. Schoenborn, Charles Rauch
Publikováno v:
Science. 264:965-968
A cytokine was identified that stimulated the proliferation of T lymphocytes, and a complementary DNA clone encoding this new T cell growth factor was isolated. The cytokine, designated interleukin-15 (IL-15), is produced by a wide variety of cells a
Publikováno v:
The Journal of Experimental Medicine
Pluripotent hematopoietic stem cells (PHSC) are very rare cells whose functional capabilities can only be analyzed indirectly. For a better understanding and possible manipulation of mechanisms that regulate self-renewal and commitment to differentia
Autor:
Linda S. Park, Mary K. Kennedy, Tiep Le, Courtney Beers, Timothy P. Bonnert, Kenneth Brasel, Minoo Ahdieh, June R. Eisenman, Raymond J. Paxton
Publikováno v:
Cytokine. 20(3)
Interleukin (IL-) 2 and IL-15 share the IL-2 receptor betagamma c subunits (IL-2Rbetagamma c) but have specific, unique alpha receptor subunits. We studied species specificity of human (hu), simian (si), and mouse (mu) IL-15 and found that hu and si
Autor:
Raymond J. Paxton, Lin Guo, Roy A. Black, Richard S. Johnson, Jacques J. Peschon, Rajeev M Mahimkar, June R. Eisenman
Publikováno v:
Molecularcellular proteomics : MCP. 1(1)
Proteolytic cleavage (shedding) of extracellular domains of many membrane proteins by metalloproteases is an important regulatory mechanism used by mammalian cells in response to environmental and physiological changes. Here we describe a proteomic s
Publikováno v:
SPIE Proceedings.
GPR surveys were conducted at two sites within the hillside town of Rennes-le-Château, France. The town is linked with many traditions and mysteries associated with the Templar movement and its treasure, including according to some documents, the po
Publikováno v:
Adolescence. 28(111)
The attitudes of 211 students at a university in Mississippi were investigated both before and after seeing the Public Broadcasting Film Who Is David Duke? The film provided evidence of Duke's current racism, anti-Semitism, and pro-Nazi leanings. In
Autor:
R, Eisenman
Publikováno v:
Adolescence. 28(111)
The entire population of inmates in a prison treatment program for youthful male offenders was studied (N = 43). Based on information from individual and group psychotherapy and from official files, and verified with another therapist, the following