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pro vyhledávání: '"R. Edward Watts"'
Autor:
Matthew Siegel, Pavel Strnad, R Edward Watts, Kihang Choi, Bana Jabri, M Bishr Omary, Chaitan Khosla
Publikováno v:
PLoS ONE, Vol 3, Iss 3, p e1861 (2008)
Transglutaminase 2 (TG2) is a multifunctional mammalian protein with transamidase and signaling properties. Using selective TG2 inhibitors and tagged nucleophilic amine substrates, we show that the majority of extracellular TG2 is inactive under norm
Externí odkaz:
https://doaj.org/article/5cf5c1b6f2524e95bdbec9e682de5187
Autor:
Abhijit A. Gurjarpadhye, Mohammed Inayathullah, Kwang-Min Kim, David E. Solow-Cordero, Venkata Raveendra Pothineni, R. Edward Watts, Mansi B. Parekh, Dhananjay Wagh, Jayakumar Rajadas, Mustafeez Mujtaba Babar, Lobat Tayebi
Publikováno v:
The Journal of Antibiotics. 70:308-312
Autor:
Hong Zheng, Robert P. Mecham, R. Edward Watts, Keith M. Rich, Chaitan Khosla, Tracy C. Holmes, Liya Yuan, Enrique Izaguirre, Thomas J. Broekelmann
Publikováno v:
Journal of Neuro-Oncology. 103:207-219
Glioblastomas display variable phenotypes that include increased drug-resistance associated with enhanced migratory and anti-apoptotic characteristics. These shared characteristics contribute to failure of clinical treatment regimens. Identification
Autor:
R. Edward Watts, Anthony C. Forster
Publikováno v:
Biochemistry. 49:2177-2185
Ribosomal incorporations of N-alkyl amino acids including proline are slower than incorporations of non-N-alkyl l-amino acids. The chemical reactivity hypothesis proposes that these results and the exclusion of nonproline N-alkyl amino acids from the
Publikováno v:
Journal of Medicinal Chemistry. 49:7493-7501
Human transglutaminase 2 (TG2) is believed to play an important role in the pathogenesis of various human disorders including celiac sprue, certain neurological diseases, as well as some types of cancer. Selective inhibition of TG2 should therefore e
Autor:
R Edward, Watts, Anthony C, Forster
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 805
The identification of peptide and protein ligands by directed evolution in vitro has been of enormous utility in molecular biology and biotechnology. However, the translation step in almost all polypeptide selection methods is performed in vivo or in
Autor:
Anthony C. Forster, R. Edward Watts
Publikováno v:
Ribosome Display and Related Technologies ISBN: 9781617793783
The identification of peptide and protein ligands by directed evolution in vitro has been of enormous utility in molecular biology and biotechnology. However, the translation step in almost all polypeptide selection methods is performed in vivo or in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9cb3877302d930984d699482650b053b
https://doi.org/10.1007/978-1-61779-379-0_20
https://doi.org/10.1007/978-1-61779-379-0_20
Publikováno v:
Journal of the American Chemical Society. 126:7436-7437
Engineered biosynthetic pathways provide a powerful method for generating complex molecules. Precursor-directed biosynthesis, which combines chemical synthesis and enzymatic transformations, allows non-native starting materials to be incorporated int
Autor:
R. Edward Watts, Kihang Choi, M. Bishr Omary, Matthew Siegel, Bana Jabri, Chaitan Khosla, Pavel Strnad
Publikováno v:
PLoS ONE, Vol 3, Iss 3, p e1861 (2008)
PLoS ONE
PLoS ONE
Transglutaminase 2 (TG2) is a multifunctional mammalian protein with transamidase and signaling properties. Using selective TG2 inhibitors and tagged nucleophilic amine substrates, we show that the majority of extracellular TG2 is inactive under norm