Zobrazeno 1 - 10
of 47
pro vyhledávání: '"R. Eastmond"'
Publikováno v:
British Journal of Clinical Pharmacology. 45:37-40
Troglitazone is an orally active anti-diabetic agent. Cholestyramine is an orally administered lipid-lowering agent which acts by binding to bile acids and removing them from enterohepatic circulation. Preclinical studies suggesting the potential for
Autor:
E.A Foot, R Eastmond
Publikováno v:
Diabetes Research and Clinical Practice. 38:41-51
Drinking alcohol is associated with a recognised risk of hypoglycaemia. This double-blind, placebo-controlled study was designed to determine whether alcohol taken with the evening meal alters the gluco-regulatory response to troglitazone, (TR), an i
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Publikováno v:
Journal of clinical pharmacology. 38(9)
Troglitazone, a PPAR-gamma agonist, enhances the actions of insulin on muscle and liver. It is metabolized predominantly in the liver to a sulfate conjugate and a quinone metabolite. Acetaminophen also undergoes metabolism by conjugation. This three-
Publikováno v:
British journal of clinical pharmacology. 45(1)
Aims Troglitazone, an insulin action enhancing agent, is currently in clinical development for the treatment of non insulin dependent diabetes mellitus. The objective of this study was to establish the effect of food on the systemic absorption and me
Publikováno v:
Journal of the Institute of Brewing. 81:237-241
A gas-liquid chromatographic method for the estimation of monomeric and dimeric catechin in beer is described. This method has been used to estimate the concentrations of these compounds in a number of beers, which were found to contain 0·5 to 8·0
Publikováno v:
Journal of the Institute of Brewing. 81:287-292
Haze formation in beer is claimed to involve the gradual polymerization of polyphenols and their subsequent reaction with proteins to form insoluble complexes. The mechanism of haze formation has now been studied using 14C-labelled epicatechin and di
Autor:
R. J. Gardner, R. Eastmond
Publikováno v:
Journal of the Institute of Brewing. 80:192-200
The effect of the addition of a range of monomeric, dimeric and polymeric polyphenols to beer on the rate of haze formation has been examined. Monomeric polyphenols had no significant effect on haze formation. The addition to beer of dimeric or polym
Autor:
R. Eastmond
Publikováno v:
Journal of the Institute of Brewing. 80:188-192
A dimer of catechin has been separated from a number of ales, stouts and lagers. This compound has been shown to have the same structure as procyanidin B3, which has previously been isolated from plant sources. It can be conveniently synthesized from
Autor:
R. Eastmond, David R. M. Walton
Publikováno v:
Tetrahedron. 28:4591-4599
Cadiot-Chodkiewicz couplings of arylacetylenes (I), XC6H4CCH (X = H; m-Br, -Me; p-F, -NO2, -OMe) with bromoethynyl(triethyl)silane(II), BrCCSiEt3, yield the silylated diynes, XC6H4(CC)2SiEt3, from which the terminal diynes(III), XC6H4CC)2