Type 2 diabetes mellitus, brain atrophy, and cognitive decline

Autor: Paul S. Aisen, Sarah Walter, Kenneth M. Spicer, Stephanie Reeder, Nick C. Fox, Heather Anderson, Chuang Kuo Wu, Teresa Villena, Cynthia M. Carlsson, Paul Malloy, Bonnie S. Goldstein, Stacy Schneider, Po H. Lu, Jeffrey M. Burns, Balebail Ashok Raj, Stephanie Kielb, Adrian Preda, Pierre N. Tariot, Chet Mathis, Christopher H. van Dyck, Maria Carroll, Karen E. Smith, Lon S. Schneider, Velandai Srikanth, Daniel Varon, Nunzio Pomara, Michael Borrie, Eben S. Schwartz, Gaby Thai, Susan De Santi, Dana Nguyen, Daniel C. Marson, Gene E. Alexander, Thomas O. Obisesan, Steven Potkin, Kris A. Johnson, Henry Rusinek, Nigel J. Cairns, Gad A. Marshall, Scott C. Neu, Benita Mudge, Leyla deToledo-Morrell, Jeff D. Williamson, Helen Vanderswag, Howard Chertkow, Sandra W. Jacobson, Dana Mathews, Arthur W. Toga, Saba Wolday, Douglas W. Scharre, Lidia Glodzik, Rob Bartha, Anders M. Dale, Norbert Schuff, Ging-Yuek Robin Hsiung, Rachelle S. Doody, Richard D. King, Vernice Bates, Li Shen, Barton Lane, Kristin Fargher, Chris Moran, Greg Jicha, Dan Bandy, Sara Dolen, Andrew E. Budson, Martha G. MacAvoy, Daniel H.S. Silverman, Anton P. Porsteinsson, Kathleen R. Johnson, Michele L. Callisaya, Betty Lind, Michael D. Devous, Robert C. Green, P. Murali Doraiswamy, Andrew J. Saykin, Joseph F. Quinn, Kristina Lipowski, Raymundo Hernando, Catherine Mc-Adams-Ortiz, Ronald G. Thomas, Jeffrey Kaye, Irina Rachinsky, Donna Munic, Munir Chowdhury, Bruce L. Miller, Les Shaw, Brian R. Ott, Randall Griffith, Kristen Martin-Cook, Marwan N. Sabbagh, Crystal V. Flynn Longmire, Raymond Scott Turner, Karen Blank, Effie M. Mitsis, Charles Bernick, Marilyn S. Albert, John M Olichney, Earl A. Zimmerman, Jared R. Tinklenberg, Robert A. Koeppe, Dick Trost, Howard Feldman, Laura L. Boles Ponto, M. Saleem Ismail, Alan J. Lerner, Kelly M. Makino, Pradeep Garg, Jeffrey R. Petrella, Peter J. Snyder, Norman R. Relkin, Laurel A. Beckett, Allyson C. Rosen, Devon Gessert, MaryAnn Oakley, J. Q. Trojanowki, Lisa Raudin, Stephen Salloway, Paula Ogrocki, Bryan M. Spann, Susan K. Schultz, Adam S. Fleisher, Brigid Reynolds, Jason Karlawish, Michele Assaly, John Q. Trojanowki, Kewei Chen, Enchi Liu, Mary Quiceno, Kaycee M. Sink, Jerome A. Yesavage, Sterling C. Johnson, Curtis B. Caldwell, Heather E. Johnson, Neill R. Graff-Radford, Karen S. Anderson, Richard Frank, John C. Morris, Donna M. Simpson, Tatiana Foroud, Joel P. Felmlee, Zaven Kachaturian, Magdalena Korecka, George Bartzokis, Francine Parfitt, Henry W. Querfurth, Patricia Lynn Johnson, Raj C. Shah, M.-Marsel Mesulam, Howard J. Rosen, Ann Marie Hake, Danielle J Harvey, Hyungsub Shim, Dick J. Drost, Yaakov Stern, Charles DeCarli, Brandy R. Matthews, Geoffrey Tremont, Kim Martin, Robert B. Santulli, Aliza Romirowsky, Joy L. Taylor, Ramon Diaz-Arrastia, Godfrey D. Pearlson, Mark A. Mintun, James J. Lah, Norm Foster, Matt A. Bernstein, Diana R. Kerwin, Virginia M.-Y. Lee, Bojana Stefanovic, Joanne L. Lord, Chris Hosein, Susan E. Molchan, David J. Clark, Leon Hudson, Janet S. Cellar, Karen Crawford, Richard Beare, Franklin Watkins, T. J. Montine, Ronald C. Petersen, Carl H. Sadowsky, David A. Wolk, Steven E. Arnold, Nancy Collins Johnson, Ruth A. Mulnard, Antero Sarrael, John Kornak, Amanda Smith, Owen Carmichael, Beau M. Ances, Clifford R. Jack, Meghan Frey, Martin R. Farlow, William J. Jagust, Ronald J. Killiany, Mony J. de Leon, Sandra E. Black, Javier Villanueva-Meyer, Smita Kittur, Walter Martinez, Sue Leon, Anthony Gamst, James B. Brewer, Hillel Grossman, Eric M. Reiman, Jacobo Mintzer, Stephen Correia, Kyle B. Womack, Maria Kataki, Lawrence S. Honig, Liana G. Apostolova, Peggy Roberts, Christine Belden, Michelle Rainka, Alexander Norbash, R. Edward Coleman, Richard E. Carson, Dzintra Celmins, Lisa Taylor-Reinwald, Scott Herring, Oscar L. Lopez, Michael W. Weiner, Ranjan Duara, Elizabether Finger, Peter A. Hardy, Myron F. Weiner, Horacio Capote, Keith A. Johnson, Karen L. Bell, Allan I. Levey, Steven G. Potkin, Howard Bergman, John A. Rogers, Wei Wang, Connie Brand, Chiadi U. Onyike, Paul M. Thompson, Russell H. Swerdlow, Gloria Chaing, Judith L. Heidebrink, Salome K. Bwayo, Reisa A. Sperling, Michael C. Donohue, Sanjay Asthana, Alice D. Brown, Charles D. Smith, Neil W. Kowall, Andrew Kertesz, Tamie Sather, Evan Fletcher, Sonia Pawluczyk

Publikováno v: Neurology

ObjectiveTo study longitudinal relationships between type 2 diabetes mellitus (T2DM), cortical thickness, and cognitive function in older people with normal cognition, mild cognitive impairment, and Alzheimer disease (AD).MethodsThe sample was derive

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2468b73929ec8a8e70031760e42449f7
https://pubmed.ncbi.nlm.nih.gov/31889018

Florbetapir F 18 amyloid PET and 36-month cognitive decline:a prospective multicenter study

Autor: R. Edward Coleman, Jeff D. Williamson, Gustavo Alva, Michael J. Pontecorvo, Abhinay D. Joshi, Beth Safirstein, K Johnson, Jeanette K Wendt, M N Sabbagh, Eric M. Reiman, Mark A. Mintun, Ron Korn, Terence Z. Wong, Geoffrey L. Ahern, Cynthia A Murphy, Adam S. Fleisher, Dean Wong, Richard Holub, Keith A. Johnson, Crystal V. Flynn Longmire, Carl H. Sadowsky, George Jewell, Mildred Farmer, Daniel Skovronsky, Michael D. Devous, P. Murali Doraiswamy, C H Sadowsky, Ming Lu, Ranjan Duara, Marwan N. Sabbagh, Michael Grundman, Karel D. Kovnat, P. M. Doraiswamy, Danna Jennings, Michael Weiner, Reisa A. Sperling, Alana Carpenter

Publikováno v: Molecular Psychiatry

This study was designed to evaluate whether subjects with amyloid beta (Aβ) pathology, detected using florbetapir positron emission tomorgraphy (PET), demonstrated greater cognitive decline than subjects without Aβ pathology. Sixty-nine cognitively

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a01cbf18705732c73dd7fe31a4cf06ad
https://doi.org/10.1038/mp.2014.9

Neuropathologic Heterogeneity Does Not Impair Florbetapir-Positron Emission Tomography Postmortem Correlates

Autor: Julie A. Schneider, Thomas G. Beach, Michael J. Pontecorvo, Lucia I. Sue, Abhinay D. Joshi, Barry J. Bedell, Brittany N. Dugger, Daniel Skovronsky, P. Murali Doraiswamy, Christopher M. Clark, Ming Lu, Marwan N. Sabbagh, Alan Carpenter, Monica Mariner, Eric M. Reiman, R. Edward Coleman, Geidy E. Serrano, Mark A. Mintun, Adam S. Fleisher, Simone P. Zehntner, Carl H. Sadowsky

Publikováno v: Journal of neuropathology and experimental neurology, vol 73, iss 1

Neuropathologic heterogeneity is often present among Alzheimer disease (AD) patients. We sought to determine whether amyloid imaging measures of AD are affected by concurrent pathologies. Thirty-eight clinically and pathologically defined AD and 17 n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f98abda8bef4ef943d91deebd06828dd
https://doi.org/10.1097/nen.0000000000000028

Does the Preparation and Utilization of 99mTc-Sulfur Colloid Affect the Outcomes of Breast Lymphoscintigraphy?

Autor: R. Edward Coleman, Kingshuk Roy Choudhury, Terence Z. Wong, Kasey P. Nelson, Steven Shipes, William Hubble, William L. Siler

Publikováno v: Journal of Nuclear Medicine Technology. 41:92-98

The purpose of this study was to determine whether certain factors in the preparation and use of 99mTc-sulfur colloid affected the number of sentinel lymph nodes (SLNs) detected during SLN mapping and during intraoperative SLN identification. The fac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7ada1ab87506bbd6b99d6bc049ec726
https://doi.org/10.2967/jnmt.112.117820

Cerebral PET with florbetapir compared with neuropathology at autopsy for detection of neuritic amyloid-β plaques: a prospective cohort study

Autor: Mark A. Mintun, Christopher M. Clark, Adam S. Fleisher, Alan Carpenter, Daniel Skovronsky, P. Murali Doraiswamy, Ming Lu, Marwan N. Sabbagh, Michael J. Krautkramer, Carl H. Sadowsky, Thomas G. Beach, R. Edward Coleman, Eric M. Reiman, Matthew Flitter, Michael J. Pontecorvo, Abhinay D. Joshi, Barry J. Bedell, Julie A. Schneider, Anupa Arora

Publikováno v: The Lancet Neurology. 11:669-678

Summary Background Results of previous studies have shown associations between PET imaging of amyloid plaques and amyloid-β pathology measured at autopsy. However, these studies were small and not designed to prospectively measure sensitivity or spe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::eb1d14d952cca99e2be82f25dfa78567
https://doi.org/10.1016/s1474-4422(12)70142-4